Just like absorption through inhalation, everyone is different. For example, we've had filterless smokers who couldn't handle anything over 10 mg and ultra light half packers that had to have 24. I weigh around 150 pounds, have very dry skin and a couple of autoimmune conditions which means medications tend to effect me strangely. I bought a bottle of 60 mg that had leaked in transit and ended up with probably a ml or two on my hands. It took me maybe 30 seconds to get from the living room to the kitchen and get it washed off. Afterwards I had a pretty healthy nic headache. Someone with well hydrated skin who weighs 200 pounds probably wouldn't even have noticed it.
Here's an article on it that I found interesting; http://annhyg.oxfordjournals.org/content/43/6/405.full.pdf
As for poisoning the LD50 (50% of the subjects would die) is .5 to 1 ml per kg of body weight ingested. I don't think I've ever seen a dermal version for humans.
Here's an article on it that I found interesting; http://annhyg.oxfordjournals.org/content/43/6/405.full.pdf
As for poisoning the LD50 (50% of the subjects would die) is .5 to 1 ml per kg of body weight ingested. I don't think I've ever seen a dermal version for humans.