Rather than vacuum out air, consider using a sealed container and oxygen absorbers along with a dessicant. Often used for food storage, they only absorb oxygen, leaving the now prevalent nitrogen and other trace gases.
Oxygen absorber - Wikipedia, the free encyclopedia
Not an unreasonable thought, but I don't see it as being necessary. Nothing is getting in or out of these bottles once they are sealed. And unless you only take from the bottles in an O2-free environment, just using the
juice will render the O2 absorber moot. Plus, the O2 absorber, since it is not in contact with the liquid at all, will do nothing for the O2 that is already dissolved in the PG or VG upon bottling by the vendor. This amount, however, is quite low since O2 is not very soluble at all on PG or VG.
Same thing with the desiccant material. In the beginning I thought it would be a good addition, but its going to do nothing about the trace water in the VG or PG in the bottles, and usage of the liquid will not be in a desiccating environment. Besides, for unflavored nic juice, water is not the enemy. It is flavors where water can be a long term problem, and unlike O2, PG and VG hold onto water very tightly, and its unlikely a powdered desiccant would be able to pull it out anyway.
Believe me, I want to preserve my liquid as long and as fresh as possible. But the chemistry of the components tells me that the best approach is simply clean sterile bottles, filled with little headroom, sealed well, and stored dark and cold is about as good as you are going to get.
If the other add-ons, like O2 absorbers and desiccants help you feel better about the storage, go for it. But while it seems on the surface that these are good things, I think they will have virtually zero affect, other than a psychological one. I am, however, a chemist very open to counter arguments, so if someone can prove to me that the glass or gasket/caps are allowing O2 transport into the liquid, even though the bottles I'm using are designed to completely seal a liquid in, I'm all ears.