I'd feel overall better if the alkaloid extract was characterized by a good GC/MS analysis. What I've done only represents what a competent (I hope) chemist can achieve with extremely modest means and a will to try to do something that makes a positive difference.
When I mixed up the extract, I mixed it up 400 mg to 14.4 mL final volume in PG/VG. This gave 14.4 mL of presumably 27.8 mg/mL alkaloids in 50:50 PG/VG. I know this because I made physical measurements, I weighed the extract and I measured the volumes.
This presumed concentration gives me a means to evaluate how much of the extract is actually alkaloids. Using a nicotine titration, and assuming that the other alkaloids will behave like nicotine in the titration (they won't individually, but on average, they should), the closer the determination comes to 27.8 mg/mL, the less likely any non-alkaloid is present.
Let's say the extract is half alkaloids and half non-alkaloid junk that I really don't want. I weighed out for 27.8 mg/mL. If the titration says only 13.9 mg/mL, then I have a serious problem in that half of the extract is something other than tobacco alkaloids. I purified for alkaloids, and I don't want anything else. Fortunately, as you'll see in a moment, this 50% nightmare screw-up scenario did not happen.
Since the amount I have is so little, I only determined 1 mL of the finished e-liquid, and used all the precision I could muster. The result of the titration is that the liquid determined to 27.4 mg/mL. Due to the uncertainty of measurement, this makes it indistinguishable from the concentration (27.8 mg/mL) predicted by weights and volumes. So the liquid, on average, behaves like a a mono-alkaloid base with a molecular weight right around 162.
The extract I obtained is essentially pure tobacco alkaloids, the majority (perhaps 90%) being nicotine.
Here's what it looks like when tobacco alkaloids are separated from the rest of the tobacco. I would describe this tobacco alkaloid mix as a copper brown liquid of exceptional clarity (I.E. no cloudiness whatsoever). You're looking at 0.42 mL in an approximately 2 mL vial. This is the material that was mixed with USP PG and VG to produce the ~28 mg/mL whole tobacco alkaloid (WTA, if you require an acronym) e-liquid.
One needs to be careful with this stuff. Undiluted, as pictured here, it could kill a full-grown person perhaps 8 times over, not a sport for amateurs:
My thanks to Exo for hosting this image for me.
Pictured here, I believe, is why we smoke and why the plain nicotine foisted upon us by big pharma to the tune of billions? in sales for patches, gums, lozenges, dissolvables, you name it are such miserable failures. We don't smoke for nicotine alone, we smoke for this. It happens to be largely (~90%) nicotine, but not entirely nicotine.
Is this liquid harmless? Of course not. But not pictured in this vial is most everything in tobacco that kills people when burned and inhaled.
Pictured below is everything in tobacco that does kill people. This is the amount of tobacco required to produce the 0.42 mL of purified alkaloids pictured above. This is 25 grams, around 25 cigarettes worth. Now since analogs only deliver 10%, it would take around
10 times the amount pictured here, 250 grams (~12 packs) of tobacco smoked to actually get the alkaloids pictured above into your system.
Repeat thanks to exo for hosting.
So Anti's, what do you say? If somebody is absolutely unable to break the tobacco alkaloid addiction (you heard me,
tobacco alkaloid addiction, not just nicotine!), what would you have us do? Quit or die? How about something between with a significant harm-reduction versus inhaling tobacco combustion products? This tiny amount of liquid, properly diluted in USP propylene glycol, USP glycerin, or a mixture of the two and delivered via a personal vaporizer, can likely keep a hopelessly addicted smoker from turning to cigarettes for perhaps 7 to 14 days. What do you say? Don't start with what you think "ought to be" in your idealized world, we've heard that nonsense, and it doesn't help anything but your sense of self-righteousness. Start with what "is".
Here's the problem, the worst of you are puritanical radicals. You cannot be reasoned with. It's not about harm reduction, it's about your quest to impose your will on others and stamp out tobacco use at any cost. "Don't do it or anything that looks remotely like it, you weak, character-flawed smokers!", you say.
Perfectly rational policy such as harm reduction is unacceptable, in your view it makes the totally unacceptable more acceptable. It makes your little brains explode, and you'll twist logic and facts to your agenda, spouting noble words out of one side of your mouths, while spreading lies out the other side hoping that well-intentioned policy makers will be too lazy, politically cowardly, or scientifically ignorant to see your wrong-headed disrespect for science and bizarre pseudo-scientific claims for what they are: Unsupportable lies marketed for consumption by the lazy policy-makers you hope to influence to uncritically repeat your lies with "force of authority". You market lie upon lie, with the intention that if one lie doesn't get traction, maybe another will. Ultimately you fail because what you are selling is bull****. Policy-makers and the public are
not quite, as lazy, ignorant, and callous as you need them to be. In short, you are doomed to fail, and you'll just have to be content to condemn as many people as you can to an early death.
It's a good thing you people don't have it in for automobiles. Seat belts, air-bags, and crash-test safety ratings would really piss you guys off. You'd market the assertion that the only acceptable means of transportation is walking (oh, and you've have your charts, graphs, and data to "prove" it). But short of a total prohibition on automobiles (along with anything that might get a person from point A to point B without having to walk), only a car that explodes into a hellish fireball on the slightest impact would be grudgingly tolerated.
You people are, in short, a piece of work.
Not only would you forbid people on a sinking ship access to the life-boats, you would shoot the lifeboats full of holes to force them to remain on the sinking ship.
Hell needs a special place for .......s like you.
We do need to engage those among the anti's who are not resistant to reason, and we've seen examples of anti's who are not blindly opposed to harm-reduction. We still must realize that the radical kooks aren't sitting still, and probably have it in for the non reason-resistant anti's.
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