The way I look at it, if an organization as large as the U.S. government wants to destroy a single person, well, that person is seriously SOL.
IF you had reasonable warning, which is highly unlikely, your options are very limited. Go underground, VERY deep, to the point you are invisible to modern intelligence gathering methods (damn near impossible without some major connections), relocate to a non-extradition country (and hope nothing 'unsanctioned' is assigned to retrieve or eliminate you), self-terminate, or turn traitor.
The method by which the population is controlled effectively is through fear, and the threat of potential extreme consequences. The goals are to either be not important or threatening enough to recieve this treatment, or to become powerful enough to be immune to it.
No wonder our nation has the highest per capita use of anxiolytics and anti-depressants in the world.
It's sad/mad that just by stating an opinion, a person makes themselves a bigger target. What a deal. Dark days we're in, more to come.