This study changed my whole outlook on e-cigs... for the moment at least

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j21blackjack

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http://www.e-cigarette-forum.com/fo...eissenberg-study-vindicates-e-cigarettes.html

I've been trying to work my way down to 0 nic at great sacrifice to good throat hit. After reading this study, I have decided to heck with it, and I've now upped all of my nic levels to at least 24mg to achieve some pretty great TH with all my liquids. I've never felt any effects that I would associate with nicotine intake, so if there really is no absorption then I'd rather have massive TH over thinking I'm weaning myself off nicotine, when apparently I'm probably not getting any noticeable nicotine anyway.
 

j21blackjack

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Right now it's working out great. I've been buying TV doublers and only mixing my liquid at about 4-6 mg. I've been very unsatisfied for the past few weeks at my level of TH. Vapor production was just fine, but I just couldn't feel anything. I even bought a 5v mod so that maybe it would renew my TH at low nic levels. This was a wasted effort because I ended up with just a burning taste from my cartos because I was taking longer drags trying to get a good TH. Right after reading that I put some 24mg liquid that I had all but abandoned because it was "high nic", and was blown away at what I'd been missing. Now I get all the TH I can handle at just a measly 3.7v from my Mr. Puffer (which I now use mainly as a box mod with cartos). Even my "weak" 3.2v eGo can kick my .... with some major TH now. I'm pretty much a constant vaper, so I imagine I would have had some kind of effect if I really was getting a load of nicotine. So far so good, I'll make sure I post an update if I manage to overdose. :ohmy:
 

j21blackjack

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If electronic vaporizers don't give me as much nicotine as cigarettes, I will eat my hat.

Hey, I'm not saying you don't get nicotine, but there are now multiple studies out that seem to prove there is little to no actual nicotine absorbed into the bloodstream from vaping. I have read many of the threads that argue this topic, and I know it's a hot topic among those that vape. Maybe I can find some kind of home testing kit and do a study on myself.
 

j21blackjack

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I'm not real sure I want to get more nicotine. I haven't had one single urge to smoke a cigarette in over 3 months. Plus I like to vape non-stop. Whether or not I'm actually getting any nicotine, I don't really care, but I personally don't want to be getting more nicotine. I do really want to try some of the new cartos though, but I don't have the money to spend one them right now.
 

j21blackjack

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It probably takes 10 puffs on a moderate nic. e-cigarette to equal the absorbed nicotine in a real cigarette.

So when he makes the puffs equal, it doesn't prove much.

Do you mean 10 ecig puffs should be equal to 1 cigarette puff? I agree that equal drags, ecig vs real cig, would be give greatly different results. These guys need to do a study to find out how many ecig drags would be need to equal a real cigarette. They should also use experienced ecig users instead of random people off the street. From the looks of the graphs in the study, it would appear that you would need to take a huge number of drags on the ecig to get the same effects on the body as a real cigarette. I'd go as far to say that it's probably impossible to replicate the effects of a real cigarette with an ecig simply because of how little nicotine is absorbed by vaping. You would need like a 10 minute continuous hit on an e-.... or something ridiculous to get the same amount of nicotine into the bloodstream. Also, it's a completely different type of delivery, cigarettes use combustion, while ecigs use vaporization. Maybe the temperature differences change the absorption of the nicotine, since cigarettes are actually burning, and ecigs are simply heating. Smoke and vapor are about as similar as night and day.
 
I don't know if anyone has brought up the whole issue of whether or not this stuf is skipping the bloodstream and going directly to the brain, because of the absorbtion in the mucus membrane. I'm no expert or anything but I know that there are a whole host of drugs that do that given proper delivery circumstanses. I have definately felt the nicotine buzz on ocassion and I was a chain smoker for years before becoming a Vaper
 

four2109

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Shhhhh!! Don't tell my mother she quit nicotine 3-4 months ago when she started vaping. Mystery is how after 45+ years of a pack a day or more she had no nicotine withdrawals. ;)

Charles

Do you mean that you started her on 0 nic and she didn't/hasn't noticed?! If so, that's great!
 

The Fool

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I find this very interesting. I have to agree with Grayfox that there is something that they are missing. I smoked for 40 years, tried every nic replacement out there. I've been on patches for months at a time, I could tell within a couple of hours when I had forgotten to put on a fresh patch, I would start to get antsy. When I was using lozenges and I stepped down from 4mg to 2mg I could really tell the difference. I guess what I'm trying to say is that I am acutely sensitive to changes in my nic level....fuzzy thinking and irritability being foremost. I have had NONE of those problems with vaping. 7 months and none of the usually side effects of quitting smoking.
 
It seems most vapers have personally noticed nicotine effects at different levels, and all agree more research is needed.

What I don't understand is why larger stakeholders in the ecigaretter industry haven't paid for clinical studies already? Surely it'd be cheaper and more productive down the road then stalling the FDA in court has been.

Even if Big Tobacco never enters this industry (fat chance...), the FDA or SOMEONE will eventually have to hook these devices up to smoking machines in a lab and publish quantifiable results.

This situation BEGS for a grant writer & medical professionals.
 

7thCabal

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From what I understand it just takes a little longer for your body to metabolize vaporized nicotine vs. incinerated nicotine in smoke form... something about the ppm in both forms of delivery.
Also a 2sec drag off a PV does not equal a 2sec drag off of a cig.
The whole "we don't get nicotine from these things(PVs)" IMHO is... well, skewed.
 

The Fool

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Another thought that I had was that part of what we call around here *the learning curve* could be learning how to get our nicotine from vaping. I know that it is not unusual for me to be taking in another hit while simultaneously blowing vapor out my nose....I never smoked that way.

I'm very glad that the study was done, because it's a start, more studies will come.
 

Craymar

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Do you mean that you started her on 0 nic and she didn't/hasn't noticed?! If so, that's great!

No. She is using 18 and 24mg juice but the study clearly shows that e-cigs don't delivery nicotine into the bloodstream lol. So she must have just gave it up cold turkey according to the study.

/Sarcasm Off
I don't know how she is getting her nicotine from them, but you can bet she is. Highly unlikely she would have been able to stop smoking if she wasn't getting her nicotine fix. It would be great if she really was not getting nicotine and she really was off of it.
 
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Automaton

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If they aren't finding any nicotine delivered by e-cigs, they are looking at the wrong delivery system.

I feel very different at different strengths. It's not a placebo. When I first vaped 18mg I was expecting it to not be enough. I had to take a break, because I got a buzz after a few minutes. I forgot to check the strength on a juice, loaded up a carto, and it was 24mg - I was having nic OD symptoms for the next half hour. I've vaped 12mg, still gotten TH, and not felt quite satisfied.
 

j21blackjack

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Maybe I'm just weird, because I don't notice any difference whatsoever between nicotine levels, at least between 0-24mg. I haven't, and don't plan on, trying any higher than 24mg. The only difference to me is TH. At about 6mg and below, I can't feel anything. I think 24mg is going to be my limit at 3.7v though, the TH I'm getting is much more than say, smoking a Marlboro Red. Anyway, I sit at work and chain vape for hours, then get in my truck and drive home vaping. Then after the kids are in bed, I chain vape until I'm ready for bed, ~2 hours. I have never noticed any effects I could contribute to nicotine though. It does feel like I have a mouthful of cotton if I don't drink something constantly though.
 
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