tobacco alkaloid pill?

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ifpo238

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Apr 9, 2010
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Did a little more digging and found a press release on their website that they're planning to make and market the thing. This is from November:
Star Scientific Plans Worldwide Marketing and Sales of CigRx(TM) Nutraceutical in Partnership with inVentiv Health PETERSBURG, Va., Nov. 4 /PRNewswire-FirstCall/ -- Star Scientific, Inc. (Nasdaq: STSI) announced today that the company plans to introduce the CigRx(TM) nutraceutical product developed by its subsidiary, Rock Creek Pharmaceuticals, for worldwide marketing and sales in partnership with inVentiv Health, Inc. (Nasdaq: VTIV). inVentiv Health offers a complete range of commercialization solutions for every stage of the product lifecycle, in a range of healthcare categories that includes nutraceutical products. The company has marketing and sales capabilities in 40 countries around the globe. Jonnie R. Williams, Star's CEO, stated, "Cigarette smoking is the leading cause of preventable death in the world. However, the global cigarette business, which now exceeds $300 billion, continues to grow. Our goal is to make CigRx(TM) available to adult smokers worldwide who wish to maintain a nicotine-free metabolism." Rock Creek Pharmaceuticals will be responsible for the manufacturing of CigRx(TM), and the company anticipates that inVentiv Health will be involved in the product marketing and sales, with a focus on product education for physicians and health care professionals, as well as consumers.
 

TWISTED VICTOR

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Good job with the shovel ifpo238. They know what we know and they intend on showing the world. I applaud and support 'em, buy their product if I can and spread the word. And I do see a ton of resistance from BT, FDA and all the anti's. I see quite a battle around the corner, but at the same time I think Star Scientific is fully aware of what they face and stands the best chance of anyone to bring about winds of change.
 

Bagazo

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Here is a little more info on CigRx:

Rock Creek Pharmaceuticals, a subsidiary of CIGX, has isolated a naturally occurring alkoloid in tobacco called anatabine that is responsible for the calming, "feel good" effect cigarette smokers experience. CigRX is a patented nutraceutical product that will deliver this alkaloid. Obviously nicotine is addictive, but the fact that NRT products have minimal success in stopping smoking suggests that it there is another reason that smokers return to smoking; CigRX may well be the solution to this problem. The market for this application, and other immediate "off label" applications such as weight management, will be huge. And yes, treatment of other neurological conditions, such as Alzheimers, are being studied at Rock Creek.

One should not forget that CIGX just filed the first application with the FDA for a "modified risk" label on their patented hard dissolvable tobacco products, having reduced the dangerous nitrosamine levels to virtually "zero". If they don't receive the FDA modified risk label, arguably no one will. The licensing of this technology to the tobacco industry could be a game changer for the company by itself.

It doesn't seem to be WTA. Wonder if it will really cut it for everyone.
 

TWISTED VICTOR

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Good point Bagazo. Anatabine is one of many alkaloids in tobacco and, although we assume it's only part of the spectrum we've relied on, maybe it's the key one. Or maybe it's the only one they care to emphasize...... I think they understand this stuff pretty well, so maybe WTA isn't really needed...donno. Ultimately, BT and BP will have a screaming fit if this stuff works and is successfully marketed.
 

DVap

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I'm not surprised that they're focusing on anatabine. Among the minor alkaloids, it's 2nd in line (only nornicotine is more abundant). I've suspected it as one of the "things we want", but can't say if it's THE thing we want. Glad to see somebody is doing the work to find out. WTA is, after all, a shotgun approach to getting what's needed... so if anatabine alone can do the trick, so much the better.
 

Katya

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DVap, do you really believe that it can come down to just one single alkaloid? For years the thinking has been that it's the nicotine, and nicotine alone. We now know better. My feeling is that all those different components work in concert, somehow, and that picking one out, and leaving his brothers and sisters behind, cannot possibly succeed, or can it? How many times have we witnessed it with simple vitamins. Somebody discovers that people who eat foods high in vitamin A are protected from disease X; we isolate vitamin A, put it in a pill, and it not only doesn't work as well as was believed, it actually can become toxic--in higher doses and outside of its "natural habitat." We have evolved to consume whatever it is we consume in whole packages, as it comes in nature. Out ancestors ate grains, fruit and meat, not isolated molecules. They chewed coca leaves and sucked on poppy seeds and burned all kinds of fragrant sticks and twigs in order to inhale the smoke and hallucinate...

I wish them well. If I could take one little pill that could keep me calm and focused and sharp and relaxed, I'd buy a case. In the meantime, I'll play with my Thunder Frosted minis, my Stonewalls, and my batteries and cartomizers.
 

DVap

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DVap, do you really believe that it can come down to just one single alkaloid? For years the thinking has been that it's the nicotine, and nicotine alone. We now know better. My feeling is that all those different components work in concert, somehow, and that picking one out, and leaving his brothers and sisters behind, cannot possibly succeed, or can it? How many times have we witnessed it with simple vitamins. Somebody discovers that people who eat foods high in vitamin A are protected from disease X; we isolate vitamin A, put it in a pill, and it not only doesn't work as well as was believed, it actually can become toxic--in higher doses and outside of its "natural habitat." We have evolved to consume whatever it is we consume in whole packages, as it comes in nature. Out ancestors ate grains, fruit and meat, not isolated molecules. They chewed coca leaves and sucked on poppy seeds and burned all kinds of fragrant sticks and twigs in order to inhale the smoke and hallucinate...

I wish them well. If I could take one little pill that could keep me calm and focused and sharp and relaxed, I'd buy a case. In the meantime, I'll play with my Thunder Frosted minis, my Stonewalls, and my batteries and cartomizers.

As I said, I can easily see it as one of the things we want, but can't say it's THE thing. Perhaps nic + anatabine would work for more folks than nic alone, but not for everybody? Then again maybe anatabine is potent, but not so much as a pill, but would work better vaped?
 

ifpo238

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in another thread (;)), DVap postulated that ppl could be divided into 4 categories, based on their relative "need" for nicotine and "other stuff." the truth may very well be that there are many categories. if anatabine or anatabine+nic work to save even a subset of people from lung cancer, i'd call that a win.

i think it's premature to pass judgement here. this may work, it may not, or it may only work for some. at any rate, i think it's a move in the right direction, and i'm eager to see what happens next.

-jeff
 

Katya

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in another thread (;)), DVap postulated that ppl could be divided into 4 categories, based on their relative "need" for nicotine and "other stuff." the truth may very well be that there are many categories. if anatabine or anatabine+nic work to save even a subset of people from lung cancer, i'd call that a win.

i think it's premature to pass judgement here. this may work, it may not, or it may only work for some. at any rate, i think it's a move in the right direction, and i'm eager to see what happens next.

-jeff

I'm sorry if didn't make myself clear. I agree with you 100%. I'm a big fan of Star Scientific and I use their Stonewalls and Ariva. I think they are doing great research and I'm eagerly awaiting the CigEx. God knows I need all the help I can get. I'm one of those people for whom e-liquid is not enough, even though it helps. I was just asking questions. So far, snus is the preferred weapon in my anti-smoking arsenal, but I would gladly abandon snus, vaping, smoking and dissolvables if somebody offered me a pill that would make me stop mourning cigarettes. I hope and pray that they succeed. I really do.


I view myself as the person who will continue to use their Stonewall dissolvable with 4mg nicotine AND the CigEx product with its alkaloid. Together, I might find the Holy Grail.

You will continue to use CigEx? Is there something you haven't told us, Tropical Bob? Is it actually in your possession? Pray tell. The Holy Grail is what I'm after, too.
 

jamesam1243

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what i find odd after spending $2000 on ecigs, etc is that for me that Geoff's TV tobacco doubler 0 mg placed on tongue ( 3 drops ) works as well or better than any thing else i've tried to suppress my urge for cigarettes , except for cigarettes themselves, snus, and extract of macerated cigarette butts ( Not Advised )

James

August 03 smoked 00 cigs, 40 less than my usual 40 cigs a day 3198 cigarettes not smoked in 92 days by using Stonewall, Joye 510, Hello 016, Ken's BoxMod, MadVapes 2xAA Box Mod, WetBox Vaporizer (ecig) and 19 bottles of ejuice partially used , $0.28 per cig X 3198 Cigs = $895.44 diverted from cigarettes to Vaporizer (ecig). OMG I have spent over $2025.59 in 92 days on this stuff but bare in mind that my old cigarette cost was $330 a month, using snus right now ( General White Portion Mint )
 

tescela

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It appears that CigRx was launched on August 5 with Richmond, VA as the initial test market.

CigRx(TM) Dietary Supplement Launch In Richmond, Virginia Announced by Star Scientific, Inc.

GLEN ALLEN, Va., Aug 05, 2010 /PRNewswire via COMTEX/ --

Star Scientific, Inc. (Nasdaq: CIGX) today announced that CigRx(TM), a dietary supplement developed by the company's Rock Creek Pharmaceuticals subsidiary, has been launched in the greater Richmond, Virginia area. CigRx(TM), a mint-flavored lozenge that dissolves in the mouth and is swallowed, contains neither nicotine nor tobacco and was developed for adult dependent smokers. CigRx(TM) temporarily reduces the urge to smoke using a unique combination of dietary ingredients: anatabine is an alkaloid found in plants that are members of the Solinaceae family including tobacco, eggplant, green tomatoes and potatoes. It appears to interact with some of the neurotransmitter cells in the brain in a way that mimics what occurs when a person smokes a cigarette. Anatabine has been combined with an extract of the leaves of the yerba mate tree to temporarily reduce the urge to light a cigarette in any environment where smoking is prohibited or unacceptable. Yerba mate is a small evergreen tree that is native to South America. Its leaves are used to brew a tea beverage that is consumed by millions of people on that continent, and it recently has become popular in the United States as well. Those who drink the beverage believe that it provides them a variety of benefits. This combination of dietary ingredients is intended to temporarily reduce the urge to smoke.


...if anyone here has access to try this product, then please share your feedback
 

jamesam1243

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well here i go again following TropicalBob's lead and chasing my dream of not being controlled by cigarettes

Shipping Method: Ground (Residential)

Item Quantity Description Amount
---- -------- ----------- ------
CigRX10 3 CigRX Dietary Supplement, carton 79.95
contains 10 boxes.

Subtotal 79.95
Tax Rate 0.00%
Tax 0.00
Shipping/Handling 0.00
Total $79.95


Customer Service
Phone: 1-800-778-2031
Email: customerservice@cigrx.com

hope this works ok

James

August 05 smoked 00 cigs, 40 less than my usual 40 cigs a day 3278 cigarettes not smoked in 94 days by using Stonewall, Joye 510, Hello 016, Ken's BoxMod, MadVapes 2xAA Box Mod, WetBox Vaporizer (ecig) and 19 bottles of ejuice partially used , $0.28 per cig X 3278 Cigs = $917.84 diverted from cigarettes to Vaporizer (ecig). OMG I have spent over $2025.59 in 92 days on this stuff but bare in mind that my old cigarette cost was $330 a month, using snus + PV right now ( General White Portion Mint )
 
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