My guess is that it's the cable, not the USB interface. I liked the small, flexible cables, but when I measured their resistance, it was often 5 ohms or more. It wasn't a problem with the USB port supplying the power (have vaped off my laptop, and my nephews' WII USB ports without any problem). But you need a heavy-duty USB cable, the thin ones just have too high a resistance.
BTW, "Mommy, Uncle Jim's smoking the WII" is a phrase I never thought I'd hear in my lifetime! (Particularly since my name isn't Jim, I changed it to protect the guilty...)
Edit:
I've also used my handmade passthrus with cigarette-lighter USB adapters (For the car). Some work, some don't (some can't supply enough power). When they work, they're fantastic! (5V is a great voltage!) But also, the USB Connectors aren't really designed to handle the current; I weaned myself off of USB Passthrus because they kept dying on me (seems like the connector burns out; vaping an LR cart on 5V. ) Also, most juices taste better to me at 3.7 than at 5V, but that might just be me and/or my juice or cartos.