I had a similar problem with the Nautilus. So much I liked about it, but so many frustrations. Being a little *nal retentive, I took to keeping a log of what kind of juice, my setting, how long the coil lasted, and whether the bad taste was mild or foul. Then I started experimenting on the coils themselves. I went through about 10 coils before I thought I had it down. In other words, I could consistently keep a coil alive for more than a day or two. Here's the tricks I figured out
A burnt coil is a dry coil. You gotta keep that bugger wet.
When you first take the coil out of the package, put a couple of drops of juice right on the coil. Screw it into the base, set the base on the collar to hold it up, and go get a cup of coffee or something. When you come back in 5-10 minutes, put another couple of drops of juice right on those coils. Fill the tank and put it together (make sure and screw it down really tight). Now put the tank down on the collar and go find something else to do for 5-10 min.
Close down your air flow to the half way mark, and vape on low volts/watts a few times nice and slow. Don't suck on it like a straw, or you'll flood the thing and have to clean it up before you can move on.
Now you can open up your airflow, turn up the power, and vape to your little heart's content.
Couple of side notes....the Nautilus is easy to flood. Make sure you're pulling slow and easy. You can open up the corner of your mouth a little too to control the suction. If you do flood it, take off the tank, remove the coil, and wipe it all out completely (make sure to get under the drip tip too). Put it back together, and dry fire your coil in a couple of quick bursts. Then you should be good. If it's flooding, you're sucking too hard.
Also, when you set it down, set it down upright. For a few minutes is no big deal, but leaving it on it's side seems to make it a little more prone to flooding.
On the opposite side, if you set it down for a long time, the wick can dry out a little, and you could get a dry hit, or worse, a burn out. So, in the morning, after it's set all night, turn down your air flow, and give it a couple pulls without firing. Or you could open it and put a couple of drops on the coil, but that might flood it. You just need a little juice once the coil is wet. After a couple of pulls without heat, you can go back to your regular setting, and should be good.
These coils should last 1-3 weeks depending on your settings, and how much you vape.
Kind of a pain in the posterior, but totally worth it for the excellent vape off of pre packaged coils