No. Never. As much as I say I "love" my nicotine and don't intentionally reduce my nic strength, I do find myself every couple of months reducing the nic level of my liquid. I started at 18 and 24, quickly switched to 12mg, down to 6 now. Even at that level (I DIY unflavored stuff, easy way to do it), I find myself diluting my 12 and 6mg retail liquids to around the 6 and 3mg levels. I didn't "mean" to do this, my body just wants and requires less nicotine.
Even though something stupid happen, and a 15ml bottle of juice is taxed to, say, cost $30 or more, I'll likely just do what I already do. Buy it at a nic level above my needs and dilute it with VG (YMMV--I don't need a strong flavor nor a lot of nicotine). Or just make/buy zero nic stuff and "spike" it with a splash of nic when I want it. That will make my freezer nic stash last a decade or more. It'll go "bad" before I finish it, probably.