Don't let anyone tell you that nicotine is a poison...

[Cromeus]

Nicotine is highly poisonous. A teaspoon of pure nicotine is enough to kill between 60 and 120 average Americans, or 85 to 170 Asians with the commonly accepted LD50 of .5 - 1mg-kg.

Why it's unlikely to the extreme to cause an OD in vaping is because we only absorb about 10% of the nic in vaping, we vape concentrations as low as .6%, and even vaping at 45mg in a genisis with an assumed more efficient rate of say 30% absorption, you'd have to vape 6ml of this ridiculously strong juice within the hour or two before it leaves your system. If you're above average, absorb less, or reduce any other risk, it becomes even more ridiculous.

Let's say you use mini protank 2, and go through 1ml/hour. Let's say you vape 12mg and weigh 80kg, and have a weak immune system, so 40mg in your system at once will kill you.
Let's say you have a reasonable 10% absorption rate.
You'd have to chain vape your 1ml/hour for more than 30 hours to OD.
Too bad nic is out of your system within two hours and its metabolite is gone in 16, meaning at most, your system could have 21mg floating around in it.

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[BillyWJ]

Not totally sure that's true. I believe plants have nicotine in them to help spread there seeds.
Tomatoes are delicious and give what ever eats them a small buzz wanting to eat more. After they are consumed the animal wonders off and eventually goes to the bathroom. Depositing the consumed seeds in a nice little fertilizer pile. More tomato plants grow, and the cycle continues.
This is a basic explanation but holds true for fruits and vegetables.

I tend to think the nicotine evolved in vegetables to ward off insects, which don't propagate seeds, they just destroy the plant. Which is why nicotine is an insecticide, and doesn't kill mammals in the concentration in tomatoes or eggplant or potatoes.

 

[Orb Skewer]

http://www.sciencelab.com/msds.php?msdsId=9926222
I think an msds constitutes that sufficient studies were done to determine if something is poisonous or not.

CDC - The Emergency Response Safety and Health Database: Systemic Agent: NICOTINE - NIOSH
and that's what the cdc's findings are.

The 'LD50' measurement is around 150 years old-and was formulated during a 'parlour game' - ouija board anyone?

https://www.ecigarettedirect.co.uk/ashtray-blog/2013/12/eliquid-nicotine-lethal-dose.html

 

[DC2]

Nicotine is highly poisonous. A teaspoon of pure nicotine is enough to kill between 60 and 120 average Americans, or 85 to 170 Asians with the commonly accepted LD50 of .5 - 1mg-kg.

This seems like a good place to drop this, for those that haven't seen it yet...
http://www.e-cigarette-forum.com/forum/media-general-news/476535-dr-farsalinos-nicotine-dosages.html

 

[Orb Skewer]

Nicotine is highly poisonous. A teaspoon of pure nicotine is enough to kill between 60 and 120 average Americans, or 85 to 170 Asians with the commonly accepted LD50 of .5 - 1mg-kg.

Why it's unlikely to the extreme to cause an OD in vaping is because we only absorb about 10% of the nic in vaping, we vape concentrations as low as .6%, and even vaping at 45mg in a genisis with an assumed more efficient rate of say 30% absorption, you'd have to vape 6ml of this ridiculously strong juice within the hour or two before it leaves your system. If you're above average, absorb less, or reduce any other risk, it becomes even more ridiculous.

Let's say you use mini protank 2, and go through 1ml/hour. Let's say you vape 12mg and weigh 80kg, and have a weak immune system, so 40mg in your system at once will kill you.
Let's say you have a reasonable 10% absorption rate.
You'd have to chain vape your 1ml/hour for more than 30 hours to OD.
Too bad nic is out of your system within two hours and its metabolite is gone in 16, meaning at most, your system could have 21mg floating around in it.

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Now listen here Roswell !!

 

[BillyWJ]

Any substance consumed in excess can / will kill you. But I'm not sure there have been any real scientific studies showing nicotine is deadly Or harmful in any meaningful way.

Google "nicotine poisoning" and you will find quite a few scientific studies and case studies on it. Tobacco farmers and workers around tobacco leaf have a specific kind of poisoning called "Green Tobacco Sickness" from getting nicotine overdoses handling raw leaf tobacco.

The good thing is that to get 100% pure nicotine in any quantity, you have to manufacture it, it occurs in smaller doses in nature.

 

[BillyWJ]

This seems like a good place to drop this, for those that haven't seen it yet...
http://www.e-cigarette-forum.com/forum/media-general-news/476535-dr-farsalinos-nicotine-dosages.html

This creates with something I read a few weeks ago, and now can't find (of course), that showed 600mg as being the "fatal" dosage level, not the ridiculous "2 cigarettes worth" that's thrown around, mostly by our faux press.

If it only took 2 cigarettes to kill you, then it would be the easiest and cheapest method of suicide going, yet how many people do you see threatening to eat a pack of Marlboros?

 

[DC2]

Sounds like we may want to define "poisoning" a little bit more clearly...

Poisoning as in you will die?
Poisoning as in you will get sick and puke?

The former is a reason to ban nicotine, which I don't think it justified by any theorized "imminent danger" based on the numbers.
The latter is a good reason to let "the children" experiment with nicotine, as it may just teach them not to use it.

I know when I once drank too much vodka as a teen I became averse to vodka for many years.
Even the smell made me want to puke, and vodka is damn near odorless.

 

[generic mutant]

Not totally sure that's true. I believe plants have nicotine in them to help spread there seeds.
Tomatoes are delicious and give what ever eats them a small buzz wanting to eat more. After they are consumed the animal wonders off and eventually goes to the bathroom. Depositing the consumed seeds in a nice little fertilizer pile. More tomato plants grow, and the cycle continues.
This is a basic explanation but holds true for fruits and vegetables.

Green tomatoes contain lots of nicotine because they aren't ready to be eaten. Red tomatoes much less.

MMS: Error

The idea that vegetables evolved anything in order to get herbivores 'buzzed' to get them to eat them is just... I don't know what to say.

 

[Izan]

http://www.sciencelab.com/msds.php?msdsId=9926222
I think an msds constitutes that sufficient studies were done to determine if something is poisonous or not.

CDC - The Emergency Response Safety and Health Database: Systemic Agent: NICOTINE - NIOSH
and that's what the cdc's findings are.

I think, based on the information sited above, I would be hard pressed to ACCIDENTALLY poison myself with nicotine.
Presuming the studies used 100% nicotine, how much of my 1.0% juice will I need to consume? 50 ml? 100ml?


The information presented is great, but with no analysis, it is noting more then Blah blah blah...FUD!

Cheers
I

 

[John_]

I think most people that consider nicotine a poison (or at least the only way I could understand their argument) are referring to what it causes the body to do, this combined with existing conditions are what is harmful.

 

[etchie]

Chocolate is a poison as well. That's why when you eat a lot of chocolate you get sick. Getting sick like that makes you not want to eat any more and is the reason people don't overdose.


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[DC2]

Chocolate is a poison as well. That's why when you eat a lot of chocolate you get sick. Getting sick like that makes you not want to eat any more and is the reason people don't overdose.

I have often experimented with how much See's Candies I can eat before I get sick.


I did get really sick one time at my girlfriend's house whilst helping her family make their annual Christmas Candy Village.
I got a really bad headache and had to lay down for a few hours.

I'm a sucker for sugar.

 

[tj99959]

Well if nicotine was a poison, we'd all be dead!

Fact is that the CDC has never tested a person ... NOT ONE ... that tested negative for nicotine in their system (it's called the "background level".

It's also a fact that not just for humans, but for all living animals, cognitive development would not have happened without nicotine. So life would have never developed much beyond that of an amoeba without nicotine in the food chain.

 

[Robino1]

Chocolate is a poison as well. That's why when you eat a lot of chocolate you get sick. Getting sick like that makes you not want to eat any more and is the reason people don't overdose.


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Chocolate is loaded with caffeine.

 

[rico942]

I puked bad when I swallowed reprocessed tobacco spit. Man never have friends that dip or chew then decide to use the left over beer bottle as a spittoon. When there are 20 beer bottles on your table make sure you pick the right one.

Did it many times...well all of my friends have... we all lived through it. He would buy you beer for the night too.

Man, I saw this once, a guy who accidently took a big swallow from a spit bottle. First time I ever saw "projectile vomiting", it was immediate and violent, like his stomach just collapsed ...

So its hard to believe that anyone could ever even intentionally poison themselves with nicotine ...

As for the concept of "poisoning" by second hand exposure, its just too absurd to consider ...

 

[generic mutant]

Awesome:

Are bees addicted to caffeine and nicotine?

 

[p.opus]

Drink 30 ml of 24mg/ml e-juice and tell me it's not a poison.

30 ml is not a tremendous amount of e-liquid. 24mg/ml is not a lot of nicotine.

Yes, there are other products out there that are dangerous in that concentration as well, such as bleach, and draino.

But to go up and state that Nicotine is not a poison when .72 grams of it can kill you or make you very sick is pretty dang irresponsible.

 

[boog]

some info here:

How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century - Springer

 

[Moedog]

Ha, well I know it will disgust some people, but hard core dippers and chewers intentionally swallow varying quanities of juice. Yeah, I did it when I dipped Copenhaven--yeah, just part of the habit and just enhanced the experience. Amazingly I never had any bad effects....