Not a single pleasure of life is worth giving up for five years more dribbling at the end of it.
Emp
Emp
Has this question gone to Ruyan or have they avoided the issue? I'm interested also.Glycerine is also incredibly sweet, so getting it in the mouth is not at all unpleasant. I have no idea why it isn't used instead of PG in the the commercial nicotine solutions. Dr. Loi has been using glycerine, too.
Acute/Chronic Hazards: This compound may be harmful by inhalation, ingestion or skin absorption. When heated to decomposition it emits toxic fumes of carbon monoxide and carbon dioxide.
WHAT!?
Don't panic. I''m sure that's referring to those with allergies to PG, like VP. The same way they refer to rare side effects in medical literature.
4.1.3 Repeated dose toxicity
Early studies (Seidenfield et al., 1932) showed no toxicologically adverse changes in rats
given 10% propylene glycol in drinking water for 140 days, equivalent to a NOAEL of
13200 mg/kg bw/day. Although higher treatment levels were included in this
investigation (25% and 50% in drinking water), they provide no meaningful information
since the animals died midway through the study (69 days) from dehydration and
starvation.
5.4.2 Inhalation Studies
Species: male/female Sprague-Dawley rat
Method: not given
Exposure
Period: 6 hours/day, 5 days/week, 90 days
Concentrations: 0, 160, 1000, 2200 mg/m3 in atmosphere; nose only exposure
GLP: no data
Results: During second week and following, nose bleeding occurred as a result
of dehydration effect from Propylene Glycol on nasal tissue. At
highest dose, reduction of body weight and decrease in food intake by
female rats was observed. No clear dose related changes of clinicalchemical
and hematological parameters were detected. Neither
organs (liver, kidneys, spleen and lungs) nor blood examined showed
any sign of toxicological effects.
That may be meaningful, however there are numerous human foods that are toxic to dogs or cats, including chocolate, onions, tomatoes, grapes...I also find it interesting that PG was denied for use in cat food, but it is used in human food?