Nicotine and Cancer Linked? Links Included

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hairball

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You constantly post the negatives about ecigs. Here is my question to you..if you are so concerned with your health then why did you smoke and continue to use such a "harmful" substance like nicotine? If you truly cared about yourself, you would stop everything.

"Cigarette smoking can nevertheless trigger the development of cancer, stresses Chellappan. By-products of nicotine and other compounds are to blame, though, rather than nicotine itself." - Guess you need to read How nicotine helps cancer grow - health - 21 July 2006 - New Scientist a little better huh?
 

nomadman

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That right there tells me either you didn't read them or you have no understanding of what you just read.

um...

"To determine whether nicotine works on the cellular level to promote breast cancer growth, Yuan-Soon Ho, Ph.D., of the Taipei Medical University, and colleagues, looked at 276 breast tumor samples from anonymous donors to the Taipei Medical University Hospital, to see whether subunits of the nicotinic acetylcholine receptor were overexpressed in breast cancer cells compared with surrounding normal cells. "

"The authors write: “These results imply that receptor-mediated carcinogenic signals play a decisive role in biological functions related to human breast cancer development.” "

"it has been demonstrated that nicotine promotes the growth of solid tumors in vivo, suggesting that nicotine might be contributing to the progression of tumors already initiated"


Yes, I see now. They ARE all about smoking cigarettes. You are correct.

I guess my reading comprehension must be off. My mistake.

You are much smarter than me. Thank you so much for putting me in my place
 
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illillillillilli

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Thanks for the link. I just want to point out the the research for the links I posted are much more current. The Duke Today link is from 2001 while mine are from 2006 and 2010. It is always a good idea to look at publication dates to stay on top of current ideas and approaches.

Yes, and those benefits are still true today. I was just saying. No need to be a Negative Nancy on a pro-vaping forum. derp! I think that's why everyone thinks you're a troll. It's like going to a vegetarian forum, and posting about the benefits of eating meat. Someone's been dippin in the FDA Kool-aid.
 

nomadman

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You constantly post the negatives about ecigs. Here is my question to you..if you are so concerned with your health then why did you smoke and continue to use such a "harmful" substance like nicotine? If you truly cared about yourself, you would stop everything.

"Cigarette smoking can nevertheless trigger the development of cancer, stresses Chellappan. By-products of nicotine and other compounds are to blame, though, rather than nicotine itself." - Guess you need to read How nicotine helps cancer grow - health - 21 July 2006 - New Scientist a little better huh?

Yep, according to that article nicotine may cause cancer to grow quick. For those that may have cancer that is important news.

But the 2010 article states:

"The authors write: “These results imply that receptor-mediated carcinogenic signals play a decisive role in biological functions related to human breast cancer development.”

So the more recent research indicates that Chellappan may have been wrong in his statement. Again with the dates...
 

nomadman

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Yes, and those benefits are still true today. I was just saying. No need to be a Negative Nancy on a pro-vaping forum. derp! I think that's why everyone thinks you're a troll. It's like going to a vegetarian forum, and posting about the benefits of eating meat. Someone's been dippin in the FDA Kool-aid.


I do not see the original post as negative, but offering up information that is relevant to this section of the forums. If you don't like it then that is a personal problem.
 

emus

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I don't know the long the term effects of vegetables, fish, eggs, red meat or ecigs.
I do know ecigs have tangible short term benefits.

Small samples not statistically relevant. In my circle I've lost too many non-smokers to cancer and the smokers died of other causes.

I feel COPD is less likely w/ ecigs and cancer is caused by about everything.

Good luck on finding what doesn't cause cancer.
 

nomadman

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I don't know the long the term effects of vegetables, fish, eggs, red meat or ecigs.
I do know ecigs have tangible short term benefits.

Small samples not statistically relevant. In my circle I've lost too many non-smokers to cancer and the smokers died of other causes.

I feel COPD is less likely w/ ecigs and cancer is caused by about everything.

Good luck on finding what doesn't cause cancer.

I agree with the limitations of the small sample size, but it does indicate that future research should be done. COPD is also my biggest fear from analogs. I am an avid outdoorsman and not being able to breath scares the hell out of me.
 

mrjaguar

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unless I'm mistaken, just about everything on earth can cause/promote some form of cancer.. I understand that we should be careful about things that are bad for us, but MY own opinion is that when I consider all the crap that I inhaled from all of the inhale-able crap I've used, e-cigs seem to be the least offensive. I'd be willing to bet that e-cigs are better for me than my energy drink, or my coke zero. it's all a matter of perspective I guess. my perspective is that this is WAY better for me than anything else I've done before. including quitting smoking analogs with no "aids" or whatever.. when I quit smoking I turned into a Psychotic raving lunatic. enough so that once, the owner of a company I worked for (who is a total non-smoker and detests everything about it) walked into my office, threw 5$ on my desk and said "go buy yourself some smokes.. I can't deal with the amount of ...... you are"

that's just my opinion. take it for what it's worth.
 

Anima

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I, for one, appreciate the links to the articles. This section of the forum, IMH noob opinion, should be a "safe place" to discuss these types of concerns. I'm a happy vaper, and nicotine is for me a very beneficial drug (it's very good for ADHD and depression with no noticeable side-effects), but I also have concerns about the long-term consequences of heavy vaping and nicotine use. There's no doubt that vaping is much safer than smoking, but there are a lot of really unhealthy habits that can be characterized that way.

Vaping does, at times, seem a little too good to be true. It's a risk I'm obviously willing to take, because I haven't seen any evidence that I'm doing myself any real harm, but I do have some reservations. Based on these articles, vaping after a cancer diagnosis is probably a bad idea. Since some people may quit smoking and start vaping because of a cancer diagnoses, I think it's good information to have.
 

Hiryu

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I think you all who went on to attack Nomad should be ashamed of yourselves.

So what if he's posted some concerns about e-cigs? Is not like he's there simply screaming that the sky is falling, he has been posting research and data, and if anyone sees something wrong with that, then you have issues beyond help.

Yes, yes. We all love our e-cigs, but we cannot go on a protectionist crusade whenever someone comes and provides any information that may or may not threaten your perceived status quo. The attacks Nomad has been the target of are NOT warranted or deserved, and yes, I have read his posts.

Debate and discourse should not be discouraged, specially when skepticism is involved. Going around touting our e-cigs as a perfectly safe and even health-improving device would be naive and a certain way to destroy our credibility with non-vapers - most of all, the antis. We know it is safer than smoking for sure, yes, but the fact of the matter is, we DO NOT KNOW IF IT'S SAFE.

Safer than smoking does not equal innocuous, and I think ostracizing ANYONE for providing any information that could help us figure out what harm, if any, e-cigs do is childish, immature, self deluded and a disservice to vapers as a whole.

How is this attitude different to quit-or-die forums flaming anyone who comes in touting the wonders of PV's? If you want to debate him, then prove him wrong. Show you research, your numbers and your scientific studies to help him see the other side of the coin, but DO NOT flame him or hypocritically call him a troll when he is not being one.

What kind of place is this? Everyone talking about what a great community this is and what a lovely bunch of people who treat everyone like family this is, but is it really?

Or is it that people will be nice to you only as long as you play the part of e-cig crusader and unyielding supporter?

Are we only a family as long as nobody rocks the boat and says anything against the almighty PV?

Just to reiterate.

You should be ashamed.
 

illillillillilli

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Read and read over these articles, it aimed at cancer cells already present. Growth, not cause. Thank goodness I switched to vaping instead of smoking a pack-a-day. Thank goodness I quit worse things than cigarettes with more immediate effects. Sober and legal for 5 years now! Nic and caffeine are the drugs are my drugs of choice now. :thumb:
 

Tendril

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Hi nomadman,

Thanks for posting those links and bringing the discussion forward. It's great to hear that you've recently found vaping and I hope you enjoy it :thumbs: I'm sorry if some of the responses to your topic were a bit reactionary. Please note that it's the forum rules not to respond to flames (which can be a good practice beyond the forums too).

One of the common characterizing attributes of vaping is a consciousness of our health. And one of the common questions I get is "isn't it nicotine that's the problem?" Or rather, I often hear that nicotine is the problem (usually from smokers with two scoops of hostility). I'm interested in reading anything on the potential dangers of nicotine so that I can talk to others about it and understand the research myself.

If we're confident in the safety of our PVs we should be inviting these topics
 

JW50

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I, for one, appreciate the links to the articles. This section of the forum, IMH noob opinion, should be a "safe place" to discuss these types of concerns. I'm a happy vaper, and nicotine is for me a very beneficial drug (it's very good for ADHD and depression with no noticeable side-effects), but I also have concerns about the long-term consequences of heavy vaping and nicotine use. There's no doubt that vaping is much safer than smoking, but there are a lot of really unhealthy habits that can be characterized that way.

Vaping does, at times, seem a little too good to be true. It's a risk I'm obviously willing to take, because I haven't seen any evidence that I'm doing myself any real harm, but I do have some reservations. Based on these articles, vaping after a cancer diagnosis is probably a bad idea. Since some people may quit smoking and start vaping because of a cancer diagnoses, I think it's good information to have.

I'm a little confused. OK to vape (presumably with nic) until one has cancer - then quit? Presume it is true - nicotine both causes cancer and promotes the growth of cancer if one has it. Options to avoid: Smoking doesn't work, snus doesn't work, vaping with nic doesn't work, pharm inhalers don't work, nic gum doesn't work, nic lozenges don't work, eat tobacco plants - that doesn't work, eat tomatoes - that doesn't work , potatoes - that doesn't work, eggplants - that doesn't work, tomatillos - that doesn't work, sweet peppers - that doesn't work, hot peppers - that doesn't work. What is your recommendation?
 

Pamdane

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Getting very tired of this.

I just found these two articles... they are worth reading.

The first is here:

Nicotine Binding to Receptor Linked to Breast Cancer Cell Growth

I've had ENOUGH!!!! The actual study was of SMOKING nicotine.

Breast Cancer: Fight Now by Dr. Aaron Tabor: Green Tea EGCG Suppresses Breast Cancer Cell Growth

The other is here:

Journal of Clinical Investigation -- Nicotine induces cell proliferation by β-arrestin–mediated activation of Src and Rb–Raf-1 pathways

and a less technical review of it here:

How nicotine helps cancer grow - health - 21 July 2006 - New Scientist

The first states that nicotine may "directly promote the development of breast cancer"

The second discuss how nicotine may boost the growth of existing cancer.

Comments?


http://breastcancerfightnowbydraaro.../green-tea-egcg-suppresses-breast-cancer.html
 

Pamdane

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JW50

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I just found these two articles... they are worth reading.

The first is here:

Nicotine Binding to Receptor Linked to Breast Cancer Cell Growth

The other is here:

Journal of Clinical Investigation -- Nicotine induces cell proliferation by β-arrestin–mediated activation of Src and Rb–Raf-1 pathways

and a less technical review of it here:

How nicotine helps cancer grow - health - 21 July 2006 - New Scientist

The first states that nicotine may "directly promote the development of breast cancer"

The second discuss how nicotine may boost the growth of existing cancer.

Comments?

Do you have recommendations for the vaping community? Should all stop in taking nicotine? What if that will not work for some. What do you suggest as best option then? Smoking, lozenges, inhalers, etc.? With these research papers - have they affected your behavior? How?
 

emus

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I'm a little confused. OK to vape (presumably with nic) until one has cancer - then quit? Presume it is true - nicotine both causes cancer and promotes the growth of cancer if one has it. Options to avoid: Smoking doesn't work, snus doesn't work, vaping with nic doesn't work, pharm inhalers don't work, nic gum doesn't work, nic lozenges don't work, eat tobacco plants - that doesn't work, eat tomatoes - that doesn't work , potatoes - that doesn't work, eggplants - that doesn't work, tomatillos - that doesn't work, sweet peppers - that doesn't work, hot peppers - that doesn't work. What is your recommendation?

Countless things cause cancer and that's a tough one to avoid. Lung cancer is top of the list.

80-90% COPD deaths are from smoking. COPD is the third leading cause of death in the USA. Perhaps ecigs are less likely to cause COPD. Many have reported improved breathing w/ ecig.
 
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