I've been researching nicotine physiology's relationship with addiction. It seems clear to me the addictive potential of nicotine directly correlates to it's speed of absorption i.e. why patches are less addictive than inhaling burnt tobacco. Anyone out there share my interest in this subject. I would argue that this is one of the reasons why ecigs appear to be a far more effective replacement to smoking than conventional NRT.
Nicotine Physiology
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Nicotine is easily absorbed via the skin. Its easy to get a nic overdose (dizziness, sick,etc) from patches that are too high dosed for your normal consumption.
Patches are just as addictive but lack all charm. They hardly work for anyone in the long term. They are cumbersome and expensive all the same.
It is by far one of the least pleasant ways of taking nicotine.
Patches are just as addictive but lack all charm. They hardly work for anyone in the long term. They are cumbersome and expensive all the same.
It is by far one of the least pleasant ways of taking nicotine.
The studies show nicotine absorption is way lower than that of cigarettes and is comparable with NRT. I think that the main reason for the e cig success is not only the nicotine, but the hand to mouth addiction we seem to have from smoking. And the inhale and exhale of the vapor.
Nicotine absorption from electronic cigarette use: comparison between first and new generation devices
Nicotine absorption from electronic cigarette use: comparison between first and new generation devices
I personally believe there are two fronts that make cigarette smoking so addictive. One as you suggest is the rate of absorption. I was a cigar smoker for many many years. There were times during fall or spring that I would smoke a cigar every single night for weeks on end... Yet during the winter I wouldn't touch one and never felt any sort of addiction to them. I believe this is because since cigar smoke is not inhaled and nicotine is only absorbed through the mouth and saliva, it is delivered at a much slower rate despite there being much more nicotine in an average cigar than there is in an entire pack of cigarettes.
I also believe however that nicotine is only a part of the addictive substances in cigarettes. I believe that there are other chemicals which have an even stronger addictive mechanism than the nicotine itself. In fact, if you spend much time on this forum you'll find many people who either quit vaping and find it MUCH easier than quitting cigarettes, or people who cut their nicotine levels in half (i.e. 24mg to 12mg or 12mg to 6mg) and have no problem doing so. Try telling your average smoker to cut their intake in half and i'm sure you'll see quit a struggle. Yet the delivery method of vapor to the lungs has to be at least as effective (i.e. fast) as cigarette smoke... So why the discrepancy if it's based on absorption time alone? That's why I believe there are other chemicals playing a part.
I also believe however that nicotine is only a part of the addictive substances in cigarettes. I believe that there are other chemicals which have an even stronger addictive mechanism than the nicotine itself. In fact, if you spend much time on this forum you'll find many people who either quit vaping and find it MUCH easier than quitting cigarettes, or people who cut their nicotine levels in half (i.e. 24mg to 12mg or 12mg to 6mg) and have no problem doing so. Try telling your average smoker to cut their intake in half and i'm sure you'll see quit a struggle. Yet the delivery method of vapor to the lungs has to be at least as effective (i.e. fast) as cigarette smoke... So why the discrepancy if it's based on absorption time alone? That's why I believe there are other chemicals playing a part.
Interesting... Just saw Katmar's post... Wasn't there when I started typing my reply...
Apparently my assumption that it's just as fast at delivering as smoking is wrong... I'm surprised... Unless of course some of the chemicals also included in cigarette smoke speed the absorption rate.
Apparently my assumption that it's just as fast at delivering as smoking is wrong... I'm surprised... Unless of course some of the chemicals also included in cigarette smoke speed the absorption rate.
Definitely some of the chemicals speed absorption rate.
Nicotine and Tobacco Addiction | Be Tobacco Free.gov
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