From what I have read, for vaping, there actually may be somewhat more danger in "organic" flavors than in the synthetic ones, just because diketones *are* naturally-occurring substances -- and in foods we eat or drink, no problem -- it's the inhalation that makes them tricky. So I have no issue as far as them being synthetic. Yes, at some point some other chemical(s) may rear its head and turn out to be dangerous, and if so, we'll deal with it if/when it arises -- but for now, we don't know *for sure* about any except the diketones, and I'm not even sure we do know *for sure* about those -- it would SEEM that they are potentially very dangerous to the lungs, so it's got to be better to avoid them wherever and whenever we can.
Some might say that the "v2" flavors I'm using aren't as good as the "real" ones, the originals, and that may or may not be true, but I have nothing to judge them by -- I've never tasted the diketone-laden flavors, that I know of, so the diketone-free flavors taste just fine to me.
Andria
the problem with natural vs synthetic is moot.
synthetics have nasty stuff in them precisely because
the natural flavors have them. their what gives the flavor,
its flavor. synthetic flavors are molecularity the same as
their natural counterparts.

regards
mike