OMG........Vaping Gelatin!

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LisaLisa

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Hubby is allergic to both types of glycerine, it gives him a terrible sore throat respiratory problems, but he is desperate to vape something so he can get off analogs.

I've been thinking for a week about what other types of liquids he could vape, and this morning I thought of knox gelatin.

Not sure how it would vape, I stirred a little dry gelatin powder into some water, and put it in the vaporizer to see if it would produce smoke and how it would react.

It worked! No taste and produced the same amount of vapor that the glycerine produces. Now I'm going to get some food flavorings and mix him up some stuff so he can vape.

Anyone else know of any other glycerine alternatives that can be vaped?
 

geeker

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Neither here nor there
Someone here once suggested to make the eliquid into a gel form. Then you could sort of make a gelatin plug to put in a cart, and as it melted it would release the nic. Not sure what became of the idea, but I think generally no one wanted to inhale gelatin.


Edited to add: It is animal protein, just so you know. I don't think I'd want it clogging up my lungs.
 
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geeker

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Neither here nor there
The glycerine and propylene glycol are changed by the heat of the atomizer and metabolized after inhalation. They are tiny molecules. Proteins are GIGANTIC strings of amino acids, probably thousands or millions of atoms apiece, and they are not going to be metabolized unless they are digested first.
 

LisaLisa

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The glycerine and propylene glycol are changed by the heat of the atomizer and metabolized after inhalation. They are tiny molecules. Proteins are GIGANTIC strings of amino acids, probably thousands or millions of atoms apiece, and they are not going to be metabolized unless they are digested first.

Oh, then I guess it wasn't such a great idea afterall......:(
 

Kurt

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Oh, then I guess it wasn't such a great idea afterall......:(

No, I don't think it is a good idea. I agree with geeker. Proteins in the stomach are chopped up with peptic enzymes into the separate amino acid building blocks. No problems there. Proteins absorbed in the lungs will not break down, and instead enter the system as whole proteins. This could well cause a SERIOUS allergic reaction, as the system tries to rid itself of a foreign protein. I would think there is a risk of major allergic response, like someone who is severely allergic to bee stings getting stung. You may not experience this, but someone else might. The system does not like protein invaders.
 
As for PEG, at first glance I am leery of vaping poly-anything. Polymers in the lungs are not something I would want, as big molecule are not easily absorbed, and could cause nodules. Do you have problems with VG?

Interesting point. From memory, I believe PEG, at least in weights 200+ (those used in vaping), are pretty much inert digestively and mostly just pass through. However, what happens when PEG is inhaled is unclear - would it be absorbed, slowly re-exhaled or build up there?

I came across this product research for delivering dry particles of insulin mixed with high weight (solid) PEG (I did skim the article somewhat so might not be dry, though the details are deliberately obscured somewhat to protect their idea); seems to suggest that PEG is efficiently absorbed, or just the insulin? Interesting, nonetheless.

This article is from 2004 so one wonders what became of the idea. Particle build-up in the lungs over time? On the face of it, doesn't seem like a good idea to inhale particles (and the article does hint at slow release - through slow absorption?.

Insulin inhalation--Pfizer/Nektar Therapeutics: HM... [Drugs R D. 2004] - PubMed result

btw, my current estimation of the heat stability of PEG in the 200-400 range is that there is a slight decomp issue, perhaps less than for VG.

ps: gelatin will almost certainly not vaporise, will be a dry-residue and just burn on the coil. The fog noticed was probably rmnants of the previous liquid.
 
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TaketheRedPill

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Interesting point. From memory, I believe PEG, at least in weights 200+ (those used in vaping), are pretty much inert digestively and mostly just pass through. However, what happens when PEG is inhaled is unclear - would it be absorbed, slowly re-exhaled or build up there?



I came across this product research for delivering dry particles of insulin mixed with high weight (solid) PEG (I did skim the article somewhat so might not be dry, though the details are deliberately obscured somewhat to protect their idea); seems to suggest that PEG is efficiently absorbed, or just the insulin? Interesting, nonetheless.



This article is from 2004 so one wonders what became of the idea. Particle build-up in the lungs over time? On the face of it, doesn't seem like a good idea to inhale particles (and the article does hint at slow release - through slow absorption?.



Insulin inhalation--Pfizer/Nektar Therapeutics: HM... [Drugs R D. 2004] - PubMed result



btw, my current estimation of the heat stability of PEG in the 200-400 range is that there is a slight decomp issue, perhaps less than for VG.



ps: gelatin will almost certainly not vaporise, will be a dry-residue and just burn on the coil. The fog noticed was probably rmnants of the previous liquid.





this was interesting: "Advanced PEGylation technology to develop a dry powder-inhaled polyethylene glycol (PEG) formulation for delivering peptides efficiently across the lungs and to promote prolonged serum concentration of the peptide. PEG is a neutral, water-soluble, nontoxic polymer comprising any number of repeating units of ethylene oxide. PEGylation is designed to increase the size of the active molecule and ultimately improve drug performance by optimising pharmacokinetics, increasing bioavailability, and decreasing immunogenicity and dosing frequency. "


so, same question I have about PG or VG's effect on nicotine comes back up - are PG/VG/PEG et al, "holding" the nicotine in the lung tissue and it's more of a time-release effect (slowing the absorption), which is why we see low serum levels, And, low exhalation levels?



back on topic...

I don't think geletin would be a good idea. Proteins and food colorings. bleah. Sorry your sweetie is allergic. It's gonna be tough to be banned to gum and patches, but if you both work together on quitting analogs, I bet you can :)

TTRP
 

bitey

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Here's another consideration on PEG. A number of us who are allergic and/or very sensitive to PG had the same symptoms from vaping PEG. I had terrible pain just like I do with PG. The other symptoms were the same as well for me.

Frankly, if your husband can't tolerate PG, then you need to look into whether the flavoring in the VG based juice you bought contained PG. Unless the juice is a tobacco flavor, the flavoring will have PG in it. The label won't tell you. When I write to the flavoring companies, they tell me that "natural and artificial flavoring" includes PG.

You can get tobacco flavors, menthol, some chocolate (or mocha), and some red bull without PG in the flavoring if you are really careful. Other flavors, like fruit flavors, sweet flavors, fun flavors all contain PG in the flavoring even though it isn't listed and it says "VG." That only means VG base, not PG free.

Try him on some VG unflavored with a totally new atomizer so there will be no residue present. If he doesn't have the symptoms, at least you then understand the problems he's had with various juices. Don't give up until you have truly exhausted all of the possibilities. Good luck to both of you.
DIY flavorings all contain PG as well.
 
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