Got this off a previous post's links:
"
Health Information
The toxicology database for PG has been reviewed and agreed upon by the Organization for Economic Co-operation and Development (OECD) SIAM15 process. The oral toxicity of PG is low. In one study, rats were provided with feed containing as much as 5% PG over a period of 104 weeks and they showed no apparent ill effects.16 Because of its low chronic oral toxicity, PG is generally recognized as safe (GRAS) for use as a direct food additive. Since 1942, it has been included in New and Non-Official Remedies as a proper ingredient for pharmaceutical products and it is listed in the United States Pharmacopoeia. It is also widely used and accepted as an ingredient in dental preparations.17 PG is not approved for use in cat food.
Prolonged PG contact is essentially non-irritating to the skin. Undiluted PG is minimally irritating to the eye, and can produce slight transient conjunctivitis (the eye recovers after the exposure is removed). Exposure to mists may cause eye irritation, as well as upper respiratory tract irritation.18 Inhalation of the PG vapors appears to present no significant hazard in ordinary applications. However, limited human experience indicates that inhalation of PG mists may be irritating to some individuals. Therefore inhalation exposure to mists of these materials should be avoided. In general, Dow does not support or recommend the use of PG in applications where inhalation exposure or human eye contact with the spray mists of these materials is likely, such as fogs for theatrical productions or antifreeze solutions for emergency eye wash stations.19
PG does not cause sensitization and shows no evidence of being a carcinogen or of being genotoxic.20"
Propylene Glycol
"
Health Information
The toxicology database for PG has been reviewed and agreed upon by the Organization for Economic Co-operation and Development (OECD) SIAM15 process. The oral toxicity of PG is low. In one study, rats were provided with feed containing as much as 5% PG over a period of 104 weeks and they showed no apparent ill effects.16 Because of its low chronic oral toxicity, PG is generally recognized as safe (GRAS) for use as a direct food additive. Since 1942, it has been included in New and Non-Official Remedies as a proper ingredient for pharmaceutical products and it is listed in the United States Pharmacopoeia. It is also widely used and accepted as an ingredient in dental preparations.17 PG is not approved for use in cat food.
Prolonged PG contact is essentially non-irritating to the skin. Undiluted PG is minimally irritating to the eye, and can produce slight transient conjunctivitis (the eye recovers after the exposure is removed). Exposure to mists may cause eye irritation, as well as upper respiratory tract irritation.18 Inhalation of the PG vapors appears to present no significant hazard in ordinary applications. However, limited human experience indicates that inhalation of PG mists may be irritating to some individuals. Therefore inhalation exposure to mists of these materials should be avoided. In general, Dow does not support or recommend the use of PG in applications where inhalation exposure or human eye contact with the spray mists of these materials is likely, such as fogs for theatrical productions or antifreeze solutions for emergency eye wash stations.19
PG does not cause sensitization and shows no evidence of being a carcinogen or of being genotoxic.20"
Propylene Glycol