A while ago I put some MFP ejuice (its an intense orangy/anise concoction) in my Reo Grand and I noticed that the tubing in the bottle really swelled up and got longer after a short time soaking in the juice. It never clogged, but was very obvious. Yesterday I put some of my famous homemade 60:40 peppermint lime juice (I use lime oil) in my Reo mini and within about an hour it was completely clogged, as in I could squeeze the bottle with vice-grips and no squonking of juice occurred. I took it all apart, rinsed it out, and put in a different juice and it worked fine. The only difference I can think of right now is that with the Reo Grand, the bottom of the tubing has a V-cut in it, but the tubing in the mini is flush cut across the bottom, so maybe when these oil containing juices caused the tubing to swell, it pushed the mini tubing into the bottom of the bottle preventing any juice flow? Not sure what the moral of this story is, either don't use oil based ejuices, or if you do, make sure your tubing has a little V-cut on the bottom?