Probably not because it looks like this email is legit, I got a letter from the O.P.
I don't know how your computer handles links from email, it might be different than links online.
HOWEVER, even though this probably DID come from the Federal Gov't, remember the White House gave the petitions to Mitch Zeller of the FDA to answer. It is in the FDA's interest for us to click the links and use up our comment BEFORE casaa is done giving us guidance.
As far as giving feedback to what we think of that response to We The People, I have no idea if it would do any harm, or if it would do any good.
For the actual FDA comment, please wait for casaa.