Scientific Publication: Analysis of Electronic Cigarette’s Cartridges (Trehy et al. 2011)

[Thulium]

Just curious.How do you know that Vapor is the perfect descriptive word for what you inhale from ecig?.

Here's Wikipedia's definition of each:

Smoke is a gas and comprises a collection of airborne solid and liquid particulates and gases[1] emitted when a material undergoes combustion or pyrolysis, together with the quantity of air that is entrained or otherwise mixed into the mass. It is commonly an unwanted by-product of fires (including stoves, candles, oil lamps, and fireplaces), but may also be used for pest control (cf. fumigation), communication (smoke signals), defensive and offensive capabilities in the military (smoke-screen), cooking (smoked salmon), or smoking (tobacco, ........., etc.). Smoke is used in rituals, when incense, sage, or resin is burned to produce a smell for spiritual purposes. Smoke is sometimes used as a flavoring agent, and preservative for various foodstuffs. Smoke is also a component of internal combustion engine exhaust gas, particularly diesel exhaust.

A vapor (American spelling) or vapour (see spelling differences) is a substance in the gas phase at a temperature lower than its critical point.[1] This means that the vapor can be condensed to a liquid or to a solid by increasing its pressure without reducing the temperature.
For example, water has a critical temperature of 374 °C (647 K), which is the highest temperature at which liquid water can exist. In the atmosphere at ordinary temperatures, therefore, gaseous water (known as water vapor) will condense to liquid if its partial pressure is increased sufficiently.
A vapor may co-exist with a liquid (or solid). When this is true, the two phases will be in equilibrium, and the gas pressure will equal the equilibrium vapor pressure of the liquid (or solid).

Because nothing is combusted or pyrolized, there is no smoke. Smoke contains bits of partially burnt solids and sticky liquids that is collectively called "tar" as well thousands of byproduct gases and chemicals. Vapor, on the other hand, is chemically identical before and after vaporization--it has only changed in form from a liquid into a vapor that can be condensed back into a liquid by changing the temperature or pressure.

 

[Vocalek]

In a phone conversation the other day, Bill Godshall mentioned to me that the 4 chemicals that the FDA keeps calling "tobacco-specific impurities" are not impurities at all, but naturally-occurring alkaloids. Just ran across this today: Star Scientific launches immune-boosting supplement | News content from New Hope 360

Star Scientific has launched new supplement containing anatabine citrate, combined with Vitamins A and D3, believed to assist the body in maintaining anti-inflammatory support.

Here is a wiki article on the alkaloid:

Anatabine - Wikipedia, the free encyclopedia

 

[rolygate]

There is an interesting feature of e-cigarette vapor that is not normally noted: there isn't much PG or VG in it. Although there is no single complete analysis of e-cigarette vapor that lists every single component including water by percentage (as far as I am aware), there are several partial analyses. The most complete of these lists 82% of the ingredients including the water content.

In that analysis, it was shown that the vapor consisted (I seem to recall) of 66% water, 3% PG, 1% VG, 1% nicotine, and the rest alcohol (for some reason) and unlisted flavorings.

This seems to conflict with a passing comment by Dr Laugesen that the vapor probably consisted mainly of PG, though this was I believe a guess as no full analysis was conducted. The water content of exhaled vapor would probably be even higher, since people continually exhale water vapor that is not normally visible.

I looked at this because several vendors have made marketing claims that e-cig vapor 'is water vapor' although there is no evidence for this (in other words they are saying that it is entirely or almost exclusively water vapor). However, it seems that it is not that far from the truth. I would have expected the PG content to be much higher.

Note that any analysis that does not include the water vapor as a percentage can be dismissed, as it is impossible to interpret the true percentage of the constituents.

For more complete info see the Technical Research forum.

 

[nopatch]

Smoke is obviously a misnomer but Vapor cannot be an accurate term to describe the MIST we inhale from ecigs.

 

[nopatch]

The analysis by Healthnz guy of newzealand cannot pass scientific scrutiny.The measured PG concentrations cane near Air saturation values.Anybody who has some basic understanding of Vapor liquid equilibrium can point out mistakes made in measuring Propylene glycol concentration.One has to measure the concentrations dynamically and not after the inhaled(Mechanically) air came to equilibrium(When static).

The healthnz guy study shows what is lacking in ecig studies: competence.

 

[rothenbj]

Smoke is obviously a misnomer but Vapor cannot be an accurate term to describe the MIST we inhale from ecigs.

Perhaps you should take that argument to these people-

Products: Zero Toys Online Store

 

[nopatch]

Michael L. Trehy, Wei Ye, Michael E. Hadwiger, Terry W. Moore, James F. Allgire, Jeffrey T. Woodruff, Shafiq S. Ahadi, John C. Black & Benjamin J. Westenberger (2011): ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES, Journal of Liquid Chromatography & Related Technologies, 34 (14): 1442-1458.
Authors affiliation: Food and Drug Administration, Division of Pharmaceutical Analysis, Saint Louis, Missouri, USA

Abstract:

Here is a full text of the study.

As per the study cixi failed miserably.Njoy also has problems with nicotine labeling while Johnson creek eliquid is consistent.

 

[emus]

IMO, as a community of folks with a common interest, we should welcome any and all data .. whether that be good or bad .. while many may feel the need to defend and trumpet the benefits they seem to have gained using a PV, it's real information that is needed ..

Unfortunately, a common thread I see throughout much of ECF is

1) Immediate attempts to discredit any post that is negative / FDA related / etc
2) Immediate attempts to convince any poster with a possible health issue that it is not PV related

I find this ironic .. I joined this Forum to gain a source of information .. and I don't expect all that information to be positive ..

I've seen negative vaping info on ECF.

I have only experienced positive health benefits to date.

I don't expect unbiased info from any organization.

Issue I have is organizations like ALA position themselves to ban ecigs instead of research possible benefits. I thought their mission is to research ways to improve lung health w/ donated money.