Of course, there is no one answer to your question, because personal preference plays a role, particularly with the high end gear. I play with the high end gear almost exclusively now. Surprising, I chased the vape like many do and ended with the top of the line stuff. There are a few that meet your criteria that I've tried, but there's many I haven't tried, and will probably never own. Anyway, my two cents:
1. Provari with a great carto tank. The Kir Fanis tanks are nice looking with the Provari (I like the Privadero the best). I like Phiniac tanks.
2. Semovar with Kayfun 3.1 in hybrid mode is a setup that I use and dearly love. Maybe my best "easy" setup vape. You will need to rebuild the Kayfun, but compared to most gennies, it's a piece of cake.
3. Just GG and Ithaka is very nice and perhaps the best mechanical and topper hybrid in the world. The Ithaka is one of the most difficult rebuildable atomizers. I use mine all the time, and do not plan on buying another mechanical. Of special note, Imeo, the builder has said he will not build another mech, and will be entering the world of APV's. Why? He says there's no where left to go in mechanicals. He believes that his latest devices incorporate everything in a mechanical that can be incorporated. That's saying a lot, and as one of the world's best designers, it thought provoking.
4. DNA20 devices. I'm not big on the box form factor (YMMV), and, until recently, that is how you got a DNA20. The Cyborg is out and the Futura is out or almost out. I'm getting one of these. However, rumor has it that the DNA30 will be released on December 27, 2013. Given the hefty price, I'll wait for the new board, and wait still longer for it's incorporation into a tube APV, which I will most certainly buy.
Honorable Mentions:
1. Caravela. Can't get one, not going to bid on one. Why it may be the best is not fully understood by me, but I am open to learn more about it. Since joining ECF, I've heard about this device but haven't read about anyone actually having one yet. I'm sure they're here somewhere.
2. Otto Carter. Great GG mechanicals with top of the line engraving. As much art, as function.
There are literally hundreds of very good to great mechanical devices and rebuildable atomizers on the market, many of which are just a personal preference. Gennies (RSST and AC9 my favorite) of dozens of designs, botton coil chimneys like the Taifun and Kayfun, among others, are now very popular (my favorite), resistance/non-resistance devices like the Ithaka, Odysseus, Penelope, Diver, etc. are another type. The list is almost endless, and there are hundreds of devices that I will never try or get a chance to buy that some vapers will certainly swear by. Makes it confusing, huh?
I've had a money is no object approach for a year, and I don't think I'm any closer to getting there (wherever there is) than I was when I started. I've made a respectable start though, and I do love the better gear, because it's.......BETTER. Yes, turns out that vaping is like everything else. The best quality gear, does cost the most, and often provides the best vape. That being said, you can get a great vape on a Twist/Spinner and a Protank II/iClear30S. All about what you like, and not a question that can ever be answered. Good luck to you and welcome to the Forum.