can nic be absorbed under the tongue(equivalent to sublingual medicine) without inhaling into lungs?...sort of like cigar style
simple question
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I have no resources to back up my statements, but since I've been vaping (almost 5 years now) I've read that most of the nicotine in vapor is absorbed in the mucous membranes of the mouth, throat, and nasal passages (and not so much in the lungs).
The rationale for the above is allegedly the nicotine molecules in vapor are larger than the nicotine molecules in smoke, so the larger molecules don't get into the tiny alveoloar sacs of the lungs where most absorbtion takes place in the lungs.
When handling nicotine in liquid form, it is extremely important to be aware of absorbtion via contact. If nicotine gets on your skin, wash it off within minutes. Liquid nicotine is not meant to be consumed orally or sublingually.
The rationale for the above is allegedly the nicotine molecules in vapor are larger than the nicotine molecules in smoke, so the larger molecules don't get into the tiny alveoloar sacs of the lungs where most absorbtion takes place in the lungs.
When handling nicotine in liquid form, it is extremely important to be aware of absorbtion via contact. If nicotine gets on your skin, wash it off within minutes. Liquid nicotine is not meant to be consumed orally or sublingually.
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I don't believe this matters too much. Time wise, take a puff like you would a cigarette.
Most "tanks" require that you take a longer, gentler draw compared to a cigarette draw. This is because if you took a hard short draw on your tank you might flood the tank.
I think you need to check up on that. It's already been shown that the molecule size of vapor isn't as effective with absorption in the lungs as it is in the mucous membranes. I'm on my phone and can't get the info.
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Actually, there are no "molecule" of vapor. It is one of a funny things said by Dr. Farsalinos. He is prone to such type of statements. So, I can safely repeat: nothing is better than lungs in nicotine absorption. OK, may be stomach, but I doubt we should drink juices.
welp
i put some 3mg nic into my tank and did 3 pulls of each for about 2 secs
i let the vapor just float around in my mouth and released after 5 secs
and def felt the nic
no inhale into lungs....placebo?
put 1.5mg into the tank and def needed more to quench the craving like 4 to 5 pulls
i put some 3mg nic into my tank and did 3 pulls of each for about 2 secs
i let the vapor just float around in my mouth and released after 5 secs
and def felt the nic
no inhale into lungs....placebo?
put 1.5mg into the tank and def needed more to quench the craving like 4 to 5 pulls
Scientific fact. Vapor molecules are larger than smoke molecules produced by a cigarette. Cigarette chemicals and nicotine are absorbed much more readily by the body than e-cigarette vapor is.
I think y'all mean to say "particles". A nicotine molecule is a nicotine molecule, and it's the same size as every other nicotine molecule regardless of whether it's in a vapor droplet or a smoke particle (the actual droplet/particle, also, is going to be many many thousands of molecules in size, at least). The particles themselves (some people call vapor particles "droplets," since they are in a liquid state; some still call them "particles" in either case) are much larger in a vapor than they are in a smoke, but the molecules that make up the particle, well, they are what they are.
Sorry, there are no such "facts", there are no "vapor" or "smoke" molecules.
Thanks for link. Unfortunately only 2 pages of the paper are free, and the paper is written as an advertisement for inhaler. And anyway, it is about inhaler. Fast serach helped me to understand that oral absorption greatly depends on pH. Cigarette smoke is more acidic than cigar smoke, and oral absorption from cigars is higher. Unfortunately I did not find what proportions of oral/lung absorption are, just that for cigarettes lung absorption should be much more important than that for cigars. But anyway, with direct lung hits there are very little time for oral absorption, everything goes directly to lungs. With MTL vaping - if vapor creates alkaline condition on mucosa, then possible it has significant impact on nicotine absorption.
I don't bring vapor down to my lungs at all. Like someone else on another discussion mentioned yesterday or this morning...I also just bring it down to the lower back part of my throat. I've been getting my 6mg nic fix fine for nearly 3 years now. So I'm proof positive that lung inhale is definitely not required for nic absorption.
PS. Forgot this - In discussions with my doctor about vaping vs. smoking...he also said nicotine is absorbed much more readily in the mucous membranes, as was mentioned by others above.
PS. Forgot this - In discussions with my doctor about vaping vs. smoking...he also said nicotine is absorbed much more readily in the mucous membranes, as was mentioned by others above.
1. " it is widely accepted that fine particles (smaller than 2.5 μm) can penetrate deep into the alveolar region of the lung"
Alveolar duct expansion greatly enhances aerosol deposition: a three-dimensional computational fluid dynamics study | Philosophical Transactions of the Royal Society of London A: Mathematical, Physical and Engineering Sciences
2. "e-cigarette aerosols were found to have particle diameters of average mass in the 250-450 nm range"
Electronic cigarette aerosol particle size distribution measurements. - PubMed - NCBI
"Particle number distribution modes of the electronic cigarette-generated aerosol were in the 120–165 nm range, then similar to the conventional cigarette one."
So, let's forget forever the tall tale about big vapor particles that cannot infiltrate lungs.
It was never said that vapor particles couldn't be absorbed. It was said that vapor particles weren't absorbed as well as cigarette smoke.
From some of the publications you can see that nicotine absorption from vapor is on the same level or better than from cigarette smoke. Nicotine concentration in vapor is lower than in smoke, so it takes longer time for vaper to accumulate enough of it in blood. I do know, I am a chain vaper.
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