So - are we getting it or are we not - nicotine

Status
Not open for further replies.

IANAN

Senior Member
ECF Veteran
Oct 20, 2009
170
2
In search of an alternative to WTA (Whole tobacco Alkaloid Extract)

Basically I am deriving this as something that most likely would not/could not be under the FDA pervue to help increase the effectiveness of vaping- to give the something extra. Okay I am posting this if anyone wishes to follow along (I won't be sending samples ;) )...

The items for the most part should be readily available from either A. Your local Grocery Store or B. Available at most local vitamin/herbal supplement store as well as available online. Total outlay (Assuming you have coffee pot) should be about 20 USD or less. The method is relatively safe and requires no chemistry background.

What I am using/have already used (AKA What you need and experiment design);

1. A Coffee Pot
2. 4 cups of Coffee (I am using plain old Maxwell House coffee brewed to the instructions on the can- use whatever type of coffee you want)
3. A supply of dark Chocolate ( I am using Dove dark chocolate Promises brand for portion control) 3-4 squares a day
4. Herbal supplements (Brand Names listed as manufactures tend to have different processing methods, QA, Etc)... Nature's Way Cat's Claw Bark (1,455 mg strength), Swanson Full-Spectrum Passion Flower (500 mg strength), and Nature's Bounty Valerian Root (450 mg) plus Calming Blend (100 mg contains Passion Flower Extract)- 2 capsules a day

Additional notes: Have taken 50,000 I.U. dose of Beta Carotene (Vitamin A) and 800 I.U does of dl-Alpha (Vitamin E) for around 5 years now. Also am substituting 4 cups of coffee for the part of the 6-8 cups of tea I normally consume per day (Eg; will only consume 3-4 cups of tea in addition to the coffee). Am using 24 mg nicotine (Various flavors) e-liquid,obtained from e-cig.com, vaped in either a e-cig E-9 or RN4081 . Previous smoking habit was 2-3+ packs a day.

Will report on;

1. Desire to smoke
2. Mental Awareness state (Mental Fog)
3. Anxiety (Relaxed state) and restlessness
4. Perceived GI (Gastro-intestinal) effects including effects on bowl movements
5. Effectiveness of and frequency of vaping sessions to reduce cravings
6. Number of traditional cigarettes consumed (If any)

Will log the effects each day.

Methodology;

1. 2 cups of coffee in the AM, one at lunch, and one in the early evening.
2. Two capsules of herbal supplements per day (one on the AM and one in the evening)
3. Chocolate throughout the day with PV when desire to smoke instead of vape occurs

Length of time with each herbal suplement-

One week will be given for each herbal supplement and one week for no herabal suplements but with chocolate and coffee.

Suplement order;

Week 1. Cat's Claw
Week 2. Passion Flower
Week 3. No Herbal Suplements- Just coffee and chocolate
Week 4. Valerian + Passion Flower Extract (Valerian I already know takes a few days to leave the system).. This one may be cut short as I already tried Valerian for 3 days without coffee and it was effective but caused drowsiness.
 

Vaporer

Ultra Member
ECF Veteran
Jun 23, 2009
1,767
22
Away..
Ok folks,
Round one of what I designate as Liquid Analog is over.:thumb:
The less than .5ml of WTA was added to 2ml of daily stock vaping liquid for the final tapering off day following the 50% mix yesterday.
I don't expect any problems, but it's only prudent to keep a watch on it.;)

It was a pleasure to help out in more ways than one and I hope round 2 has the same successes.:D
 
Yes... Came across the same thing in the lit review/research I did.

I have very carefully chosen the herbal supplements, even though there may be others more potent than what I am using.

My suggestion was not more potent, but far more concentrated in the natural plant material and so more easilt extracted. Works out at the incredibly cheap 1 cent per ml @3.6mg/ml (10% of the nic concentration).

But I see you want to use whole herbs.

I would choose differently though even in that use because I'd want to avoid psychotropic effects.

I still have one eye on searching for an eliquid additive, for which my suggestion was the only good candidate so far (having reasonable psychoactive effect and worthwhile extrating from). Any way, will be interesting to see how it goes.

Also interesting to note how many people gravitate to coffee and chocolate (even if no alkaloids in the flavorings, could be a matter of association); quite a few are brewing their own coffee flavoring.
 
Last edited:

Kurt

Quantum Vapyre
ECF Veteran
Sep 16, 2009
3,433
3,607
Philadelphia
I think I have shown that playing with the curing would be a way to affect carboline levels (and HCAs in general unfortunately; a very blunt instrument); like any other product maker, will alter the product to increase sales.

And now it is clear why sugar is added to processed foods, even bread. And it has to do with more than sweetness. Addiction to processed foods is becoming as big a health hazard as smoking.

Maybe even more, Kin. You don't see 10 year olds with lung cancer, but you do see a huge spike in juvenile onset diabetes from high fructose corn sweetener and over-processed flour. Insulin makers cash cow.
 
Kurt - yes, syndrome X etc. But the reaction of sugars and proteins that create some carbolines could be key to creating the 'addiction to these foods.

Ianan - The MAO alkaloid phenyethylamine in chocolate is almost all metabolised before reaching the brain, and similar results are likely with other alkaloids. Inhalation might prove much more effective in reaching the brain.

Otherwise it might be better to look at precursors. (For example, at one time I would take a few grams of glutamine (an amino acid / protein) before sleep to boost human growth hormone).
 
I agree your suggestion would make a good additive to e-liquid and literature supports inhaling the substance provides a calming effect , but as you surmise, I am looking at whole herbs and easily obtainable food stuffs.

What I had in mind works out at about $3 to add beta carbolines to 300ml of e-liquid. Or 1 cent per ml.

Could be used via a simple alcohol/water soak or purified using standard acid/alkali cycling.
 

olderthandirt

Vaping Master
ECF Veteran
Verified Member
Mar 28, 2009
9,044
9,192
Willamette Valley, PNW
Ok folks,
Round one of what I designate as Liquid Analog is over.:thumb:
The less than .5ml of WTA was added to 2ml of daily stock vaping liquid for the final tapering off day following the 50% mix yesterday.
I don't expect any problems, but it's only prudent to keep a watch on it.;)

It was a pleasure to help out in more ways than one and I hope round 2 has the same successes.:D

I thought you might have been the 1st lab rat. Now that your going to be winding completely off the WTA, will be of interest.

Thanks Vaporer!
 
Ok folks,
Round one of what I designate as Liquid Analog is over.:thumb:
The less than .5ml of WTA was added to 2ml of daily stock vaping liquid for the final tapering off day following the 50% mix yesterday.
I don't expect any problems, but it's only prudent to keep a watch on it.;)

It was a pleasure to help out in more ways than one and I hope round 2 has the same successes.:D

Thanks for the informative feedback !

What was most surprising is the effect even on those who thought they didn't need it.

Hope we can see this available sometime soon.
 

Vaporer

Ultra Member
ECF Veteran
Jun 23, 2009
1,767
22
Away..
I stayed anon only to keep focused.
I figured if I started posting I'd get a lot of questions and even lurkers jumping in and I didn't want the distraction.
The test needed to be in a most natural setting as possible.
I asked DVap to set the parameters and it covered the 2 days he calculated for the amount sent. Seeing the reduced usage left enough for a 50% day 3.
As you can see all attempts were made to get the most data from what was available.

Initially DVap sent enough for 2 days. Upon seeing the results I noticed enough volume left for a 3rd day at 50%. Good for 2 reasons and the results were posted. The withdrawl step down I considered at that point and to see if 50% was as good , or if short did the 1/2 life of the WTA give me a chance to "catch up" during the day.
Then the remaining rather than a short good straight usage seemed better served as another step down. Just ratoinal thinking and being responsible to help avoid any possible pitfalls.
Started off this morning making the final mix and a Discreet mint snus.
So far so good.........no wanting to scratch my brain or anything. lol

If anyone has questions that weren't covered in what I communicated to DVap to post
ask away. I gave him full permission to post my comments directy as is. He did mod a couple of phrases keeping the same content to protect my identity by association.

My best to the lucky round 2 selectees!
 

Vaporer

Ultra Member
ECF Veteran
Jun 23, 2009
1,767
22
Away..
Elf,
The answer to your question is in the thread if you read back.
I kept a detailed log as any good experiment should for reference later on.
I PM'd DVap my comments, feeling effects 4-6 times each day. I also gave him permission to post them , quoted if necessary.
I really don't know when the 1st mention of the "missing something",ie the "X Factor" began.
Actually , I thought I was the 1st to mention it, noting eliquid missing something, but its really a moot point unless you need self recognition/gratification. Which I don't.
What's most important is someone made it aware in the forum and many agreed to having the same need or symptom.

Eliquid and PV's seem to be the best NRT going. They have the highest success rate with less constituients than analogs. Since ther is no actual combustion, we are talking thousands less than an analogs and even less in some "safer" tobacco products.

With eliquid the ease of quitting analogs is actually pretty easy if the nicotine level is sufficient. That to is discussed in this thread and DVaps original thread:
http://www.e-cigarette-forum.com/fo...erest-determining-nicotine-dvap-new-post.html
Long one, but a great read.

Ok, even though eliquid allows many to quit analogs, there appears to be something missing. The feeling of wellness, the claming, relaxed feeling, a feeling of contentment.
Its noticed by many with each describing it in thier own way. Still, something that would be nice to have if possible in vaping.

After lengthy discussions on what it might possibly be and the fact that snus, a more raw form of tobacco, seemed to help fill this void. So alkaloids and MAOI's entered the picture as the most likely to be what was removed from eliquid.

Enter DVaps WTA. An extract tof raw tobacco trapping the alkaloids out to be added to eliquid to see if that feeling, craving missing portion could be found.
Wel......it does fill that void and quite nicely I might add.

In summary, the addiction to analogs goes way beyond the myopic FDA's "it's nicotine" answer and offering they have for us. Oral fixations , and many other things play a significant role. The WTA is just like smoking an analog with the missing effects now not missing just a little slower being noticeable.
 
Last edited:

TWISTED VICTOR

Vaping Master
ECF Veteran
Sep 14, 2009
3,461
67
61
The edge of Mayhem
Today's research into carbolines was the most exciting by far, and will not likely be repeated.

Thanks for all the leg work and translation, kin. Even I understood :). Now didn't I say Pall Mall made the perfect drug :mad:.

In search of an alternative to WTA (Whole Tobacco Alkaloid Extract)

Basically I am deriving this as something that most likely would not/could not be under the FDA pervue to help increase the effectiveness of vaping- to give the something extra. Okay I am posting this if anyone wishes to follow along (I won't be sending samples ;) )...

:thumb: Neat. We'll watch for updates. Seems my 25mg/day Passion Flower plan might need revised :confused:.


Ok folks,
Round one of what I designate as Liquid Analog is over.:thumb:
The less than .5ml of WTA was added to 2ml of daily stock vaping liquid for the final tapering off day following the 50% mix yesterday.
I don't expect any problems, but it's only prudent to keep a watch on it.;)

It was a pleasure to help out in more ways than one and I hope round 2 has the same successes.:D
I wondered. Your calm dimeaner(stoopid spellcheck) is admirable. :cool: Personally, I couldn't stay seated while reading Dvaps post on the first day. Wet myself twice today (giggle), (oops) :thumb: .


Also interesting to note how many people gravitate to coffee and chocolate (even if no alkaloids in the flavorings, could be a matter of association); quite a few are brewing their own coffee flavoring.

kin, not to be outdone by more intelligent counterparts/cohorts/partners-in-crime, I've taken it upon myself to perform a rather scientific study and I'd like to report my findings: Coffee beans don't vape worth $*&t and monosodium glutimate, well, I do have the urge for potato chips. Thought I'd report that :cry: . I'll let you take it from here.
Vaporer,

I am very curious if you could provide any more description of the exact effects and differences you noticed between WTA and non WTA. This probably would have been better answered while you were using the full strength, but hopefully you can recall it clearly still :)

Elf, check post #394 on this thread :).
 
Last edited:

olderthandirt

Vaping Master
ECF Veteran
Verified Member
Mar 28, 2009
9,044
9,192
Willamette Valley, PNW
Twisted, this ones for you!
CrackingUp.gif


Hope you don't get the red x here
 
Nice summary Vaporer.

Needing something to do, I investigated and found the first mention of 'something missing' award goes to ...

Tropical Bob (4th september 2008)

http://www.e-cigarette-forum.com/fo...tine-calculation-juice-mixer-6.html#post35727

Took him eight months though ;)

I don't seem to use that term. Probably said 'the presence of which being distinguished by its absence' :)

First mention of 'X factor':

Silk : http://www.e-cigarette-forum.com/fo...e-substitute-tobacco-smoking-2.html#post90570 26 Jan 09

I was the first person to say 'pizza is more than just dough'.
Probably the last time you'll hear that though;
it didn't really caught on :(
 
Last edited:

TWISTED VICTOR

Vaping Master
ECF Veteran
Sep 14, 2009
3,461
67
61
The edge of Mayhem

Vaporer

Ultra Member
ECF Veteran
Jun 23, 2009
1,767
22
Away..
Like I said Kin, really a moot point unless you need it and I dont. More of a comment than anything. I really can't believe you took the time to look it up.

To All:
Today went well with the less than .5ml of Liquid Analog in my 2ml of stock vape.
Did a couple of snus and felt fine. Actually vaped less still than a normal snus day.
So....still a little life in the really highly diluted WTA , some carry over fro 50% day or both?
I dont know........just sad to see it gone. A lot learned though. At least for me and I think Dvap was satisfied with the reporting and results.
Now I can be excited to see what round 2 brings on!

Since the pure alkaloid extraction is so tough to extract, I might still be looking into a snus juice add on. Its pasturized , not fermented like american stuff. TNSA'a are way reduced. I'd be happy just to strip the possible atty gummer uppers out of it. Damn, now that sounded scientific lol
 
Status
Not open for further replies.

Users who are viewing this thread