How do you think I earned the name TWISTED VICTOR? Hey, get studyin' for that final.....
So - are we getting it or are we not - nicotine
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Also, as far as supplementing the missing MAOI's, there are other sources besides tobacco, but that doesn't mean any MAOI is safe to supplement with. Syrian Rue is a strong, natural, plant-based MAOI, often used to potentiate tryptamine use. I only point this out to warn people about the dangerous interactions MAOI's can have.
There is a very small amount of MAOI activity in the chemicals contained in traditional tobacco. A plant such as syrian rue, however, has a MUCH higher content of MAOI's, and can have potentially fatal interactions with selective serotonin reuptake inhibitors (SSRI's), which are commonly used drugs in the treatment of depression.
So while snus and other sources may be suitable for supplementing your tobacco-MAOI addiction, not all MAOI sources are safe.
~CTdl
There is a very small amount of MAOI activity in the chemicals contained in traditional tobacco. A plant such as syrian rue, however, has a MUCH higher content of MAOI's, and can have potentially fatal interactions with selective serotonin reuptake inhibitors (SSRI's), which are commonly used drugs in the treatment of depression.
So while snus and other sources may be suitable for supplementing your tobacco-MAOI addiction, not all MAOI sources are safe.
~CTdl
I guess my question ultimately should be... Are there any so called anti-depressants on the market that could truely suppliment the missing chemistry from an addicted smoker? Is it possible I could search and find a doctor that would have any clue?
The article at Metabolism and Disposition Kinetics of Nicotine ? Pharmacological Reviews says that "It [nicotine] is the principal tobacco alkaloid occurring to the extent of about 1.5% by weight in commercial cigarette tobacco and comprising about 95% of the total alkaloid content (Schmeltz and Hoffmann, 1977; Benowitz et al., 1983a)."
So getting as much as 10% non-nicotine alkaloids would appear to even be on the high side.
True, there are a variety of other naturally occuring alternatives to be investigated. Some of these are currently under consideration and a few in limited trial at present. That said, what we have in a simple cigarette is the ability to stimulate, relax, focus and motivate, all rolled up in a single dose to be taken on demand/desire (fast acting). Hard to find (impossible) in less than a large handfull of suppliments....Big Pharma is also at a loss. And there's is likely no combination that could efficiently replace it. That's what brings us back to WTA
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Alkaloid can be very powerful at ug levels.
a2d, I've kept up with the SE vs FDA thread and posted that there is an odd puzzle of things happening that just should have no effect on a decision being handed down. It sure appears that something smells and is being set up before its docketed.
CTdl, this a pretty open group. We aren't judgemental as far as the participants go. Lurkers, think what ya want. I feel the openness has been a lagre part of our success of what we understand with the help of the pros here.
a2d, I've kept up with the SE vs FDA thread and posted that there is an odd puzzle of things happening that just should have no effect on a decision being handed down. It sure appears that something smells and is being set up before its docketed.
CTdl, this a pretty open group. We aren't judgemental as far as the participants go. Lurkers, think what ya want. I feel the openness has been a lagre part of our success of what we understand with the help of the pros here.
You could try supplementing the loss of the MAOI with a weak plant-based MAOI like passion flower or st. john's wort, but these still have contraindications with SSRI medications, as well as side effects of their own. The risk of serotonin syndrome with such a weak MAOI and an SSRI is probably low, but if you are on SSRI or SNRI antidepressants, I wouldn't suggest using any form of MAOI without doing extensive research on dosages and the risks associated with the combination, and even then I still wouldn't recommend combining them.
Due to the large number of alkaloids, with differing effects on neurotransmitters, I doubt you'd find a single pharmaceutical or natural drug that could replace tobacco perfectly, but if a weak, natural MAOI is what you're looking for, and you aren't on serotoninergic drugs, I'd suggest you research into Passion Flower, as it seems to have less side effects than St. John's Wort, and less MAOI activity and associated danger than the much stronger Syrian Rue and other harmala species.
And thanks for the concern TV, but it was a take-home final, already turned it in at 5. Definitely nailed it, Abnormal Psychology was a breeze, just like all my other courses in human services.
~CTdl
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No antidepressant is able to do it all, however the right one can help level you out. That's one to talk to your doctor about. I've been down that road a couple of times and I'd just as soon take my risks with smokes as to live through the side effects of the drugs. My opinion, only.
Yer killin' me here, Mister. I was stating the alkaloid content of the extracted nicotine, not the content in the baccy
.No antidepressant is able to do it all, however the right one can help level you out. That's one to talk to your doctor about. I've been down that road a couple of times and I'd just as soon take my risks with smokes as to live through the side effects of the drugs. My opinion, only.
Yer killin' me here, Mister. I was stating the alkaloid content of the extracted nicotine, not the content in the baccy
I wonder why the medical community hasn't picked up on our problem. I doubt very seriously that I will be able to find a doctor who has a clue.
Go back a bunch of posts and you'll find these discussed in some detail by kinabaloo. Boy, you ain't no dummy. ....good addition to the cause
.[/quote]And thanks for the concern TV, but it was a take-home final, already turned it in at 5. Definitely nailed it, Abnormal Psychology was a breeze, just like all my other courses in human services.
~CTdl[/quote]
Abnormal Psychology just comes naturally for some of us
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Later, a2d. And don't think BP and BT don't already know. Add that to your conspiracy notebook
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That's not what I meant.
Polar solvents do a decent job on alkaloids, and they do a great job on crud.
Hi, AirNerd. WTA stands for "Whole Tobacco Alkaloids", the stuff besides the stripped down nicotine e-liquid that make a stinky old cigarette so loveable. Go to DVap's lair and check out "It's Not Just The Nicotine" and "Whole Tobacco Alkaloid E-Liquid". That may help better than me
.http://www.e-cigarette-forum.com/forum/blogs/dvap/403-its-not-just-nicotine.html
Hi, DVap.... Honeymoon taint over yet, is it? Don't tell me the mrs. figured you out already....took Momma a few years to get a grasp on me, then a few more to grip the reality of it all .
. Honeymoon taint over yet, is it? Don't tell me the mrs. figured you out already....took Momma a few years to get a grasp on me, then a few more to grip the reality of it all .
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