Definitely go with the SMOK TFV4, blows the UWELL crown out of the water, it's the closest to a dripper i've ever seen, i'd say it gives you a near identical dripper experience, I use mine around 90 watts, but that's low to some people, quad coils rated 40-140 watts and you can easily chain vape it at 100 watts, the vapor production is in a league of its own, same as most RDA's I've seen. It's definitely the best tank on the market right now. I've used the Uwell and i'd put it behind the TFV4 in second but it's a long way to coming close to it. I find my sweet spot with the tank is 85 watts, so it'd go good with your istick 100 watt. The tri coil comes in at .2 and the quad comes in at .15 so it'd be cutting it close, IMO the tri coil performs nearly identical to the quad, I wouldn't be able to tell the difference, some people actually prefer the tri coil.