I very much enjoyed reading your post, and agree with most of your points, though I might argue with your notion that PVs are a clear and unambiguous "step forward" in the history of tobacco/nicotine delivery systems (I don't buy into the myth of progress much anyway), in part because no human activity can ultimately be isolated apart from its role in culture, the ways in which what we do are embedded in myth and ritual in the context of a collective awareness of how the significance of such things become recognized and defined. PVs don't yet have an acknowledged cultural status on our social stage, and it's not at all clear that this will be allowed to ever become the case.
The developed, post-industrial age world suffers from the virtually universal delusion that what something "is" can be revealed by a purely empirical analysis in a vacuum, which is both epistemologically narrow and ontologically wrong. On a political level, this prevailing empiricism functions to enable the designation of quick, knee-jerk tags such as "good", "bad", "right" or "wrong", providing an ever-ready justification for the oligarchic power blocs inherent in complex capital-driven social orders to proscribe this and prescribe that. The puritanical impulse to control human behavior by decree from the top-down has merely changed tactics, substituting the god of health science for the god of Abraham. But spiritually, it's the same people doing the same thing for the same reasons. Functionally, it's what the anthropologists call "the fear of contamination", exploited for the furtherance of economic and political control.
I would opine that this civilization has no notion of what tobacco or nicotine means in the world, which is reflective of the broader catastrophic dysfunctional engagement humankind currently has with the natural ecosystems of the earth and its estrangement from the other plants and animals who live here. Anyone who's truly interested might want to, say, read Black Elk Speaks, and try to understand the meaning of the Lakota story of how the pipe came to the people.
I, too, have often used the driving analogy in discussing these issues with others. The mainstream perception that a lone cigarette smoker hovering in a 5-story parking ramp is somehow singularly "harming the environment" in the context of the many hundreds of gas-guzzling/toxic fume-emitting vehicles moving in & out of the ramp every day can only be seen as a manifestation of socially-engineered collective insanity. There is no other way to look at it.