Yeah, I recall Amoret saying it could be very hard, for those with hand issues. I've had issues like that from time to time, but not for a while; I know it's probably in my future, seems to run in my family -- my grandmother's hands ended up basically just crippled, they were so swollen and painful with arthritis... but I've probably got some years left before it gets to be an everyday problem.
I mainly just like the MVP2 because of that 2600mAh, and the fact that you can use it to charge other things. And it's an innokin -- not a guarantee of wonderfulness (looking at you, SVD!), but I've been *very* pleased with my vv3's. also the MVP doesn't have that lil cage on the side like the VTR, so I can use my Kayfuns with it -- I really like the look of the VTRs, but that inability to use a kayfun except by perching it on top exactly as you do with the MVP, that's a deal killer.
Andria
I can attest - getting used to having to push harder is an adjustment.

