Triacetin

[ecavedude]

I saw this on PA and needed flavoring. I was amazed to see the report that it was OK to inhale!

"I am glad that my "smoking alternative" is working now for 24 weeks as of 9/12/2010...."

Hope this helps someone!


"Flavors - Non PG

The Perfumer's Apprentice is please to offer a new option in the world of Flavors!

We now offer many of our flavors (more to come) blended with Triacetin, instead of
Ethyl Alcohol or Propylene Glycol.

Triacetin is related to glycerin, but is not as thick, and does not have the solubility
problems that make glycerin so challenging to work with as a carrier for flavor ingredients.

It is a good alternative for people with health-related concerns about propylene glycol.

Below is a link to a study done for the cosmetics industry, but which also provides
data on food safety as well as inhalation safety. Please feel free to call us with questions."

[SIZE=+0][SIZE=+0][SIZE=+0][FONT=arial, helvetica]Link to Safety Report[/FONT][/SIZE][/SIZE][/SIZE]
​

 

[UntamedRose]

Need to look into this chemical more....but just from the report is doesnt sounds very positive...it has a lower flash point then PG/VG not sure if it's low enough to be concerned about.
Plus this safety evaluation is based entirally on is it safe on the Skin...idk about you but I'm not using ejuice as eye makeup. There may be other studies on inhaling and eating this...thats what we need to look at not if it irradiate rabbit eyes

...and the description, "oily liquid with a bitter taste and a fatty odor" Sounds like a bad move for a flavor carrier to me. (in contrast PG is described as sweet tasting with no odor)

 

[o4_srt]

Need to look into this chemical more....but just from the report is doesnt sounds very positive...it has a lower flash point then PG/VG not sure if it's low enough to be concerned about.
Plus this safety evaluation is based entirally on is it safe on the Skin...idk about you but I'm not using ejuice as eye makeup. There may be other studies on inhaling and eating this...thats what we need to look at not if it irradiate rabbit eyes

...and the description, "oily liquid with a bitter taste and a fatty odor" Sounds like a bad move for a flavor carrier to me. (in contrast PG is described as sweet tasting with no odor)

Triacetin is a generally recognized as safe (GRAS) ingredient
(21 CFR 184.1901) by the FDA. It is used in foods as a flavoring
agent and adjuvant, formulation aid, humectant, and solvent
and vehicle; it has no limitations other than good manufacturing
practice. In its determination that Triacetin was a GRAS
ingredient (FDA 1983, 1989), FDA relied upon an evaluation
on glycerin and glycerides prepared by the Federation of American
Societies for Experimental Biology (FASEB) that included
safety-test data on Triacetin. This FASEB evaluation found that
Triacetin was without toxic effects in long-term feeding studies
in rats that used doses that were higher than those to which
consumers would be exposed (FASEB 1975). In addition, FDA
contracted with a laborartory to perform a mutagenic evaluation
of Triacetin, the results of which demonstrated no mutagenic
activity (Litton Bionetics, Inc. 1976).
Triacetin is used in pharmaceuticals as a hydrophilic plasticizer
in polymeric coatings of capsules, tablets, beads, and granules,
with typical concentrations of 10% to 35% w/w (Unichema
International 1996). Triacetin is used as an antifungal drug for
treatment of superficial fungus infections of the skin (Gennaro
1990). However, data are inadequate to establish general recognition
of the safety or effectiveness of Triacetin as an over-thecounter
topical antifungal drug (21 CFR 310.545). Triacetin has
been used with prostaglandin E2 (PGE2) to form a gel used for
preinduction cervical softening (Graves et al. 1985; Noah et al.
1985). According to Yalkowsky and Roseman (1979), Triacetin
stabilized PGE.

additionally, flash point is simply the temperature at which the material needs to be heated to in order to form a flammable vapor. Auto-ignition point is where it ignites itself. FWIW, the flash point of PG is 99C, and the flash point of VG is around 176C. Not sure where you got info stating it was lower than both.

 

[ecavedude]

From the report...GRANTED it's long...

Subchronic Inhalation Toxicity
Unichema International (1996) exposed rats to concentrations
of 250 ppm Triacetin, which was produced by using heated
vapor, 5 days per week for 13 weeks. No changes in liver and
kidney weight, blood counts, or urinalysis were observed.

If you research a bit more you may be surprised

 

[UntamedRose]

PG flash point 130c....PROPYLENE GLYCOL (METHYLETHYL GLYCOL) (either way I was incorrect, thought pg was 140...so it's 8c higher)

Still have the issue of "bitter taste and oily".


My point is simply this.....this is being "advertised" as a safer and healthier alternative to PG....I'm not seeing the evidence to believe that statement at this time.

not sure "will kill athletes feet, and will soften the cervix for labor" helps that argument.

 

[ecavedude]

PG flash point 130c....PROPYLENE GLYCOL (METHYLETHYL GLYCOL) (either way I was incorrect, thought pg was 140...so it's 8c higher)

Still have the issue of "bitter taste and oily".


My point is simply this.....this is being "advertised" as a safer and healthier alternative to PG....I'm not seeing the evidence to believe that statement at this time.

not sure "will kill athletes feet, and will soften the cervix for labor" helps that argument.

"Bitter taste is DEFINETLY NOT an issue in the flavoring. Go to PA's Website...I foound out about them from this site...Just trying to pass on some info...sorry if I stated it improperly! I AQM using it and it is GREAT...Just hope it's a legit option for flavoring...remember all those other have ARTICIAL FLAVORS AND/OR COLORS ...in other words ..tons of unnamed chemicals...oh well I die using a cosmetic ..you die from a rainbow colored lung...no other way around the outcome of our choices just trying to make the way out an easy path...don't need more health issues than I already have

Best to you and sorry if I ticked you off or came off in the wrong way!

vape on!

 

[UntamedRose]

Nope not ticked.....it's quiet in the outside...just in an argumentative mood.

I've used PA's stuff....though none of what I've used has this in it that I know of. In general dont think it's bad, not the best but hardly worthless.
And a bitter taste to it.....considering PA's stuff tend to be on the weaker side and one needs to use 15-20% flavor ratio....it could be a minor to major issue.

PG being inhaled has been studied since the 1950's
http://ajph.aphapublications.org/cgi/reprint/36/4/390.pdf
http://www.epa.gov/oppsrrd1/reregistration/REDs/propylene_glycol_red.pdf
http://jpet.aspetjournals.org/content/91/1/52.abstract