Frankie1, I see your comment. I am with Nestrain. This is the comment I left:
So, this vaccine will block nicotine's "rewarding effects". Does that include the rewarding effect of maintaining normal mood and cognitive funciton? Does that also include the rewarding effect of preventing the build-up of alpha-synoclean proteins in the brain in that cause Lewy Body Dementia? This vaccine sounds like a very dangerous approach. The 40% of smokers who are using nicotine to self-medicate could end up with totally untreatable depression, anxiety, and cognitive deficits.