It all depends on where you live. Here in the Detroit area, we have a pretty amazing B&M market. Prices are generally a bit more to cover overhead but that's pretty much the only con.
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Yeah, there are a lot of vape shops around here too; I totally understand retail markup, they have to keep the lights on and such, I just choose in most cases to avoid that sort of markup by buying online. I do like to be able to see mods in person, to me they always seem much larger, in pics, than they truly are, but I won't pay +50% over a price I know I can get online. Mostly I DIY my own ejuice, but I understand that ejuice is the true profit-center for most B&M stores, and if I'm really hurting, I'll buy it retail, because at least that way I can taste it first -- and hang out with some nice fellow-vapers while I'm doing it.
But for the wildly-overpriced ejuice at one of those adult toy/paraphernalia shops... I just LMAO.
Andria