Ph-adjusted nic(salt form) vs normal freebase isn't nothing new, and there probably are or atleast where vendors doing it i.e. ph-adjusting nic by adding an acid like citric acid. The "idea/benefit" is that it lowers smell and pepper and is much less aromatic than normal nicbases, and of other traits also changes absorption some too... We can do it too I believe, if we don't like a nic in possesion and wants to tone it down by adding an acid to lowers it's PH...
Btw, in NN's description's of there salt-products they state pure nicotine is close to 8? I believe nicotine is 10-11 ph...
I think why tobacco-smoke is "salt-nic" is because there are acids in the leaf essentially ph-adjusting naturally...
Also read this old thread with some comments on this by Kurt:
pH of unflavored nic liquid?
Wow that is an OLD thread! So much I didn't know back then, pre-Box-Elder. Humbling actually. Yes there is some incorrect chemistry wording in the NN descriptions. Very incorrect in some cases. I have spoken with Jake at NN about this. Can't say much more, other than the solutions are mixtures of nicotine salts with various anions similar to the dominant forms and ratios as nic in tobacco. I have not tried them yet, but plan to very soon. At this point I am not particularly concerned about these solutions health wise. As was mentioned, nicotine salts are not new. Juul uses them, as have other inhaling technologies some years ago (but did not reach market). I know Vermont Vapor pH adjusts their 35 mg DIY nic to around pH 8 to remove smell and taste. Been doing that since 2009, at least. Other may too. Sour flavors will also product salts. Keep in mind with these NN nic salt solutions that titration kits will greatly under-measure the nic content, since that method only measures free-base nic.
The pH of 100 mg/mL free-base nic is in the high 10s. I think Jake was confusing pH with pKa of the nicotinium cation, a common mistake. A nic solution around pH 8 is about half free-base, half salt form. Lower pH than that and salt forms are dominating. I think he is shooting for pH 5 with these, which is virtually all salt form.
In terms of FDA stuff, today is simply the deadline for introducing
new products to the US market. It is not a deadline for us getting
current products or China supplying them to the US, and I believe DIY nic with high concentration is not a finished tobacco product anyway, and does not require PMTA submission, but those products will need to be registered some weeks down the road. Not sure, but it may be Dec 31. I do not know the minimum nic concentration that renders it an unfinished tobacco product. Today is just the day when the US market of currently-available
finished tobacco products freezes. What this actually means, and what supply and availability for those current products will be down the road is not clear, but I think intent to submit PMTA for post-Feb-2007 products needs to be submitted by Dec 31. Not PMTAs, just intent-to-submit statements. Up to two years for actual PMTA. This is all my understanding and if others know more or better for certain, or more details, please chime in.