Hey folks....in the spirit of trying to raise the dead and revive this group I have been thinking about fun things we can talk about besides who has the biggest gun. My dear friend CES actually put this idea in my head with her constant fear of being used as Zombie bait....LOL CES...trust me.....your WAY too valuable for so many reasons for that to happen. Some people are worth a rescue mission and your one of them.
So I thought....a great way to have some fun and really get to know each other a little is for people to think about what they have to offer in terms of survival BESIDES weapons and a propensity for violence. I think we all have more to offer than we realize. And remember , it doesn't have to be physical. Stephen Hawking is at the top of my list for people I would want around after the ZA. And even if you're not a genius maybe you have emotional or social skills that could help hold the group together. And don't forget your hobbies. What might seem like just a way to kill time could be a life saver.
So I'll start with my application for entry:
#1 I have a large collection of antique hand tools and I know how to use them
#2 I know how to sharpen a tool
#3 I can sew by hand
#4 I don't enjoy it...but if I had to I could kill and field dress just about any animal
and ok...ok...so I can't follow my own rules...what's new? But here's a photo of one of my antiques. Bought on eBay from France...dated the French Revolution. Hey...at least it's not a gun...LOL
CES....don't worry your pretty little head about answering this....I think this post adequately proves your worth
And don't forget people.....even if we DO use you for bait..hey...there is value in that. Nothing wrong with taking on for the team.
So I thought....a great way to have some fun and really get to know each other a little is for people to think about what they have to offer in terms of survival BESIDES weapons and a propensity for violence. I think we all have more to offer than we realize. And remember , it doesn't have to be physical. Stephen Hawking is at the top of my list for people I would want around after the ZA. And even if you're not a genius maybe you have emotional or social skills that could help hold the group together. And don't forget your hobbies. What might seem like just a way to kill time could be a life saver.
So I'll start with my application for entry:
#1 I have a large collection of antique hand tools and I know how to use them
#2 I know how to sharpen a tool
#3 I can sew by hand
#4 I don't enjoy it...but if I had to I could kill and field dress just about any animal
and ok...ok...so I can't follow my own rules...what's new? But here's a photo of one of my antiques. Bought on eBay from France...dated the French Revolution. Hey...at least it's not a gun...LOL
CES....don't worry your pretty little head about answering this....I think this post adequately proves your worth
There's a little bit of nic research going on, and yes there are are diseases (alzheimer's, parkinson's, schizophrenia) where it's clear that acetylcholine and nicotinic receptors are involved. But the focus is on finding pharmaceuticals that mimic nicotine's actions, but that only affect one nicotine receptor subtype (there are lots of receptor types with properties that are all slightly different and they're distributed in many areas of the brain).
the lack of focus on the effects of nicotine alone isn't really about the antz- though part of it is that nicotine is "addictive". Its also about the fact that nicotine has very broad effects because of the distribution of and activities of the many receptor subtypes. People who research nicotinic receptors and the cholinergic system in disease don't really care about the antz- the idea is to find the best, most specific treatment for a given disease.
Say, for instance, that one type of nicotinic receptor activates a region of the brain that is disrupted in a given disease state. Another subtype of receptor activates a different region that suppresses the first brain region. Ideally, you want to enhance the activity of the disrupted region, and leave the other unaffected. A drug based on nicotine that affects the receptors in the first region would do what we want it to- enhance the first without affecting the second. Nicotine would activate both brain regions, so you might not see a therapeutic effect.
Sadly, its nowhere near that easy to do well- especially since we don't completely understand the mechanisms of those diseases. It's even harder to explain clearly (as you might have noticed) so the mainstream press isn't that interested, because it doesn't translate into simple sound bites.
(the vaccine *shouldn't* affect the receptors- it binds to nicotine not nicotinic receptors. It's more likely to cause problems by binding to endogenous molecules that are structurally similar to nicotine- and that would be bad enough)
And don't forget people.....even if we DO use you for bait..hey...there is value in that. Nothing wrong with taking on for the team.