Non-smoker thinking of vaping

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mosspa

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Ok, I am done here. Dr. Leary wants everyone to believe he knows what the truth is, and if he is an actually professor with some degrees in neurosciences and not a internet nut with nimble fingers and a decent grasp of the English language, then the millions of people who endure withdrawal symptoms from both nicotine and caffeine are just faking it.
Also, you must not know anything about chemistry, cause a 10% solution (100mg/ml) of nicotine will kill you tenfold. You must be superman to inhale almost 5%.
Oh ya, I am gonna get an unscrupulous doctor to write me a prescription for amphetamitnes so I can "cheat" and become a super genius.
Hopefully the members here realize fact from fiction, experience from theory, and make their own informed decisions.

You might want to ask some of my students who are maintaining a 4.0 with a little pharmaceutical assistance.
 

stevegmu

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That may be true, at least for some, but why does that matter? You are dependent on air, yet you still breath. I fail to see a real difference. Now, let's not talk about the , probably young, OP, but me, the aging professor. If nicotine helps me in my lectures, why shouldn't I become dependent on it? Just because a person with Parkinson's Disease may be dependent on l-DOPA to function, it shouldn't mean that person shouldn't take his meds just because he is dependent on them to move smoothly..

Breathing is required for life. Addiction to nicotine isn't...Encouraging those in one's care- such as students, to become addicted to a substance borders on criminal...
 

Ablonz

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Also, couldn't the OP just use a Nicotine Patch instead of vaping for nicotine dosage? I am Not suggesting as " Sorry, you are not welcome to vape" but as a concerned ex-smoker going for the safer route vs smoking. With what I see around everywhere is that Vapers are being put into the "Smoking" category. I would not like to see a "Non-Smoker" be classified as a "Smoker" because he/she wants to have a nicotine dose for better studying or what have you..... Just a thought.
 

rolygate

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.....if you've had no nicotine in your system, then why put it there now?

The background nicotine level measurable in humans from the diet is, in the USA, 3ng/ml plasma nicotine measurement, according to Benowitz.

In other words, tests that use bloodstream nicotine presence to determine smoking status have to have a starting point well above zero in order not to give a false positive. Indeed, there is no such thing as anyone who measures zero for nicotine, since many vegetables and other foodstuffs contain it and none of the large-scale clinical surveys has ever found anyone who tested negative for nicotine. As an active ingredient in the diet, and being co-located with nicotinic acid (vitamin B3), and sharing multiple effects, it is possible (and even probable) that at some point in the future - when the taboo is sufficiently debunked - nicotine will be allocated a B vitamin number.

3ng is quite a significant amount, not far below the 6ng or 8ng that some vapers are demonstrated to find satisfactory for example, and may not always be accurate. For example, it may not apply to:

- Persons dying of starvation
- Persons who are suffering from malnutrition, with multiple vitamin deficiencies, due to lack of vegetables in the diet
- Modern urban residents who eat junk food

In any case, statements that imply some sort of zero-nicotine situation are erroneous and presumably made as the result of propaganda.
 
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mosspa

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I'm not going to enter a discussion about what milligram per milliliter means. Or what percentages are.

The definitions are in the names. No need to look them up.

The following information is incorrect. Please see post #204 in this thread for my correction.... Again, the information i posted in this post is incorrect.. I have apologized for making a stupid mistake here.

Well, you may know the names, but if you are purchasing your nicotine from somebody who puts 20mg/ml on the bottle either you're nuts, or they should be arrested for providing false labeling information. All of the nicotine containing fluids I have purchased recently have just had the amount of nicotine marked in mg on the label somewhere. In the other thread, I managed to confuse myself because this really isn't a concentration but a mass amount. My guess is that this became a juice norm because the specific gravity of PG is very close to one so one ml of propylene glycol weighs pretty close to 1 mg, and many of you don't seem to really get that science thing. Also, I'm assuming that when substituting molecules of nicotine for molecules of PG in the juice, the nicotine might make the math come out to something even closer to 1 ml of vape juice weighs one mg. Now, think about this.... if one ml of PG weighs 1 mg, how easy do you think it would be to get 20 mg of nicotine into one ml (i.e., one mg) of it.
 
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mosspa

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I didn't know that when they mark 250 ml and 36 mg nic on my bottle that what they really mean is that it is a quarter of what a liter would be..........wouldn't they just mark it as 9 mg 250 ml bottle? would that then mean a 30 ml bottle would only have about 1 mg of nicotine in its entirety?

It better be. As I just replied, I'm not really sure what it means, but it only makes any sense if they mean XXmg per liter and that the concentration is X.X.%. As I said above, I confused myself the other day, and I intend to call somebody who manufactures juice tomorrow to corroborate this. If 20 mg on a stock solution bottle of nicotine means 20mg/L or 2.0% then there would be 0.02 mg of nicotine in every ml so a 30ml bottle would have 0.6mg of nicotine in it. If this wasn't the case, then a 30 ml bottle marked 20mg would have one third as much nicotine as a 10ml bottle marked 20mg. I'm assuming that the juice manufacturers aren't that stupid. This is one case where I think that the juice guys should stop pandering to the lowest common denominator of vapers and actually put a real concentration or absolute amount of nicotine in the container on the label. However, if you don't know a milliliter from a liter, and you just read the name on the bottle, all I can say is good luck.
 

mosspa

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Breathing is required for life. Addiction to nicotine isn't...Encouraging those in one's care- such as students, to become addicted to a substance borders on criminal...

Once again.... you can-t get addicted to a substance that is not addicting. Is that so hard to understand?
 

rolygate

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Don't develop this new vape habit only to end up a smoker. There's a real danger of that happening.

No, there is no measurable, statistically identifiable or clinically significant elevation of risk of transformation to smoking status.

We have a ton of stats on that from Prof West and ASH UK, and they can't find any evidence for it. On the other hand, we may personally know someone who went from vaping to smoking, but that is termed anecdotal. If you have many tens of thousands of anecdotes then there is something to examine - but in this case we know that situation doesn't exist, because:

1. The most accurate current smoking and vaping statistics in the world, the Smoking Toolkit, tell us that does not happen.
2. Youth smoking is at an all-time low, and still falling; and youth vaping cannot be identified in significant numbers.

Apart from that, we know it is impossible to become dependent on nicotine without consuming tobacco. We know from multiple clinical trials that if you give people high doses of nicotine, daily, for months on end, that - provided they never smoked or consumed tobacco in any form - they have no signs of withdrawal and no inclination to continue nicotine consumption.

We probably knew that anyway, without all the clinical trials, since no one becomes addicted to aubergines / eggplants.

Please do not repeat propaganda here, it's really not welcome.
 
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mosspa

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Also, couldn't the OP just use a Nicotine Patch instead of vaping for nicotine dosage? I am Not suggesting as " Sorry, you are not welcome to vape" but as a concerned ex-smoker going for the safer route vs smoking. With what I see around everywhere is that Vapers are being put into the "Smoking" category. I would not like to see a "Non-Smoker" be classified as a "Smoker" because he/she wants to have a nicotine dose for better studying or what have you..... Just a thought.

No, there is no real control of dosage with patches. There is so much variation in transdermal absorption through human skin that it makes dosing really difficult. Also, it is very inefficient if you don't give it a carrier like DMSO, and even I wouldn't suggest that. It is a reasonable suggestion, however. I just don't think it will work, and why it is one of the reasons that the patch with nicotine is no more effective than a patch with a placebo in aiding smoking cessation.
 

stevegmu

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Once again.... you can-t get addicted to a substance that is not addicting. Is that so hard to understand?

Really? If one performs better on a substance over time, wouldn't it make sense they would become dependent on said substance to keep performing at the level they were while using said substance? Never heard of psychological addiction or dependancy?
 

rolygate

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That is internet myth.About the addiction part.I never realized I was addicted to nicotine until it was too late.

Smoking is addictive. Nicotine has no potential for dependence without administration of tobacco. It is impossible to create nicotine dependence clinically in never-users of tobacco.

Please read this page:
All You Need To Know About Nicotine

...then the other articles on nicotine there, then the Quotes page (for the quote by Dr Newhouse, the leading authority on nicotine administration to never-smokers), then the References page.

There is a massive black propaganda campaign run by the pharmaceutical industry and its front groups to create ownership of nicotine for themselves, just as they have done or tried to do with vitamins, herbal remedies and other nutrients. If you repeat "Nicotine is addictive" then you are just repeating pharma propaganda - there is no evidence for it.
 
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roxynoodle

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Well, my two cents...if the OP is sure s/he wants to do it, s/he will.

Does it increase concentration? I think it does. One of my problems trying to quit smoking was that I felt like I suddenly developed ADD.

I've never felt a buzz from smoking or vaping that I can remember.

I have vaped 6mg since August, and smoked 35 years. I don't think you will like 6mg, OP. Try 3mg at most.

Is nicotine addictive? Oh, heck, yes, for many people. I don't think I'm ever going to get off it, to be honest. So its something to consider. You may develop a lifelong addiction. Think about that for awhile before you make a decision.
 

deckley

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The background nicotine level measurable in the human organism from the diet is, in the USA, 3ng/ml plasma nicotine measurement according to Benowitz.

In other words, tests that use bloodstream nicotine presence to determine smoking status have to have a starting point well above zero in order not to give a false positive. Indeed, there is no such thing as anyone who measures zero for nicotine, since many vegetables and other foodstuffs contain it and none of the large-scale clinical surveys has ever found anyone who tested negative for nicotine. As an active ingredient in the diet, and being co-located with nicotinic acid (vitamin B3), and sharing multiple effects, it is possible (and even probable) that at some point in the future - when the taboo is sufficiently debunked - nicotine will be allocated a B vitamin number.

3ng is quite a significant amount, not far below the 6ng or 8ng that some vapers are demonstrated to find satisfactory for example, and may not always be accurate. For example, it may not apply to:

- Persons dying of starvation
- Persons who are suffering from malnutrition, with multiple vitamin deficiencies, due to lack of vegetables in the diet
- Modern urban residents who eat junk food

In any case, statements that imply some sort of zero-nicotine situation are erroneous and presumably made as the result of propaganda.

So very sorry for not typing a completely, time consuming statement that is 100% perfect and undeniable, unbiased and not driven by "propaganda". If you never smoked cigarettes, cigars, chewed tobacco, used snuff or a vaporizer then basically you have only ever had the normal, naturally occurring levels of nicotine in your system. Oops, forget to mention the nicotine that occurs in minute levels in food and beverages we ingest everyday.
Again, the thought was why would you change that? Doc Leary says it's fine and healthy, but why believe him? Why change the status quo? The idea was their are many alternatives to clear your mind and focus more thoroughly. Why choose nicotine?
And vaping isn't just for exsmokers, have at it if that's what you want to do. Go for it! By when you start smoking any tobacco products and then tell people you vaped first but the nicotine levels just didn't cut it and cigarettes are just simpler, apologize to all of us for making us the bad guys. And don't try to preach that crap that it can't and won't happen, cause I personally know 3 people that that's exactly what happened. Never picked up a cigarette in their life, then started vaping cause its the "in" thing, and now they smoke over a pack a day and gave their vaping gear away.
I thought this was a place for vapor enthusiasts to communicate and discuss our habits and hobby and gear, but more and more I believe I have made a grave mistake; between the pseudo sciences, l know better than you people and the constant need for people to nit pick and correct others when it's obviously just a quick remark made out of genuine concern and desire to inform and enlighten others, I must say I am disgusted.
Good bye and hope it works out for the best.
 

rolygate

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..............
Not that I have any science to back it up... but I have a hard time believing nicotine helps more with focusing than, say, simple breathing exercises or even a nice cup of tea.
...................
Compared to trying to achieve better focus by learning simple breathing exercises or brewing a pot of tea. You have introduced a 'positive' in your life. With tea, maybe doubly so if you consider the health benefits.

Not sure if you realise it, but tea commonly contains five active alkaloids, and that's why we drink it, of course: caffeine, nicotine, and 3 of the theo's.

Nicotine, either in or out of tea, could be a good idea if you're a surgeon or air traffic controller having trouble thinking straight under pressure in the early shift. There is no doubt at all it is the best choice on the efficacy vs safety scale. There are things that may work even better, but they have real negatives. Nutritional supplements like nicotine have no known negatives, just lots of positives. And as you may know, it's impossible to create dependence on nicotine clinically.

I wouldn't argue with your implication that tea, in moderation, has health benefits. You are talking about the benefits of alkaloids such as nicotine, in a cocktail that might include some other useful stuff as well. Can't have one without the other.
 
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mosspa

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well, you could begin with NO nicotine, just flavor, for example but... if you want to do nicotine, you should begin with, let's say, 6mg/ml to feel something, a throat hit.

I'm just not getting this. One of my students vapes a 20mg 50/50 mixture. I tried that in my variable voltage EVOD clone at 4.1V and didn't get any kind of throat hit, at all. Of course I'm not sure how one determines the amperage at which I was using that 4.1V, but I am lead to believe that mine is a reasonable beginner's choice system. Wgeh I up the dose to 48mg, the throat hit come through loud and clear and so does the nic buzz.
 

WattWick

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Not sure if you realise it, but tea commonly contains five active alkaloids, and that's why we drink it, of course: caffeine, nicotine, and 3 of the theo's.

Nicotine, either in or out of tea, could be a good idea if you're a surgeon or air traffic controller having trouble thinking straight under pressure in the early shift. There is no doubt at all it is the best choice on the efficacy vs safety scale. There are things that may work even better, but they have real negatives. Nutritional supplements like nicotine have no known negatives, just lots of positives. And as you may know, it's impossible to create dependence on nicotine clinically.

I wouldn't argue with your implication that tea, in moderation, has health benefits. You are talking about the benefits of alkaloids such as nicotine, in a cocktail that might include some other useful stuff as well. Can't have one without the other.

Definitely was not aware of that. Nicotine in tea, that is. Thanks! Will read up on it in the morning.

And... Well... Your links in this thread has me 99.9% convinced nicotine by itself isn't addictive in nonsmokers. Not that I doubt you. 99.9% is as convinced as I can get of anything.

If there is one thing nicotine does (for me) that is quite noticeable, is waking me up in the morning. A vape more than a cup of coffee actually. Probably because I have to be somewhat awake to even make coffee.
 
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