I've swallowed a "large drop" of 100mg/ml nic in VG before, in the name of science. First I left it on the back of my hand for 15 minutes to test for any potential skin irritation -- none was experienced -- after which I licked it off. It was kind of "warm" on my tongue, and fairly "spicy." Like store-bought "medium" hot sauce levels of heat, but without any actual flavor. I estimate I ingested about 5mg of nicotine, in total (assuming 1 drop = 1/20 of a ml, at 100mg/ml). I experienced no ill effects. It's hard to say what 300x the dose might be like, though.