Here is a link sent to me by my doctor linking nicotine with emphysema-like lesions in unborn rats. He has sent several other links which I will post once I locate them.
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That discusses an effect on a developing fetus that makes them more susceptible to "emphysema-like" lesions. It's already generally accepted that pregnant women should avoid unnecessary chemical exposures, because developing bodies are far more susceptible to many chemicals - including those considered harmless to adults, such as caffeine, alcohol and prescription drugs.
That study doesn't tell us anything about smoke-free nicotine exposure to fully-developed, adult lungs?
Regarding nicotine being "more poisonous than caffeine," we also consume less nicotine when vaping than caffeine when drinking coffee. Someone who vapes the average 3 ml of 18 mg liquid a day gets exposed to 54 mg of nicotine, yet they do not suffer symptoms of nicotine "poisoning." If the absorption rate is similar to that of smoking, the body absorbs approximately 10% of what is inhaled or 5.4 mg per day.
One 8 ounce cup of coffee contains 95 mg of caffeine.
The dose makes the poison.
That said, a dose of 30 mg to 60 mg is often cited as being deadly. However, recent research - along with cases where people ingested far more without dying or any long-tern effects - is showing that is likely not accurate. The deadly dose could be as high as 1 gram, which is 1,000 mg. (See
RealClearScience - Is Nicotine Really as Dangerous as Cyanide?) A dose of 750-1,000 mg of caffeine can cause severe toxic symptoms, similar to nicotine poisoning.
Caffeine doses of 200 mg or higher can cause unpleasant symptoms including nausea, headache, and irregular heartbeat, while dose of 750 - 1000 mg can cause severe toxic symptoms. Severe caffeine intoxication can result in nausea, vomiting, anxiety, tremor, seizures, tachycardia, dysrhythmias, hypotension, hypokalemia, and metabolic acidosis.
Several fatalities resulting from caffeine overdose have been documented, but they are extremely rare relative to its widespread use. In the case of a massive caffeine overdose, vomiting often protects against fatal poisoning, but some deaths have still resulted.
In spite of over 45 million nicotine/tobacco users in this country, like caffeine, deaths from nicotine poisoning are extremely rare. We have found only one documented accidental death (a child swallowed a smoking cessation product) in the past decade. Nicotine "poisoning" largely results in similar symptoms to the caffeine poisoning symptoms listed above and ends in vomiting (or a pumped stomach), with no lasting effects.
On the other hand, poisoning from alcohol (which is far less toxic than nicotine) kills 88,000 people
per year and can result in lasting brain damage.
So, nicotine is a poison...that has no documented deaths or lasting injuries when used as intended. To state the former and omit the latter is being a bit disingenuous.