Add MAOI to e-liquid?

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RedZone

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Robert, good to hear exercise helps control your BP.
Grief and the feeling of "helplessness" are such bad factors concerning BP.
My Dad had a heart attack on a tennis court, 20 ft from me. I carried a lot of guilt around, for not diagnosing what had happened to him, more quickly. I thought he had stumbled, and hit his head. Wasn't until he started turning blue, did the heart attack/stroke possibility sink in. He never gained consciousness, even after CPR by me, shocked w/ paddles by EMT's, successful surgery, etc. etc.

I carried that guilt, and the "what if's" around like a sinking weight. I'd never experienced depression, never been on any kind of anti meds, etc. Took me 18 months to step back on a tennis court, but only after I sought out 3rd party counseling. Took a professional to talk me through dumping the "guilt"...

Exercise and no analogs are my key to a healthy mind and BP. vaping keeps me off the analogs. So, it's all a domino affect for me, beginning w/ vaping.

I still avoid people that are high on the "drama" factor. Just don't need those kind making me think I need an analog!
 

robertpri

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Robert, good to hear exercise helps control your BP.
Grief and the feeling of "helplessness" are such bad factors concerning BP.

I did not truly understand the words, "depression" and "devastated" until wife of 33 years was diagnosed with brain cancer. She held on four weeks.

The hospice Family Counselor was great, explaining that I would be overwhelmed with a tsunami of emotions: grief, depression, guilt, anger, confusion, helplessness, insomnia, etc, etc , and all at the same time!

She said it was perfectly normal, and in fact, she would be more worried if I did not suffer hurricanes of emotions, and let them bottle up inside.

She was right. I am tryng to spend more time on the tread mill, but at 70, not exactly in the best of shape.
 

Madame Psychosis

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You might want to read my post on St. John's Wort if you are considering it. (In it, I am mostly trying to point out that it is vastly different from Wellbutrin.) I am not saying SJW is a bad idea, but always talk to your doctor first, because it may interact negatively with other drugs you are taking.
It is much more like an SSRI than an MAOI. (Passionflower extract on the other hand is a mild MAOI.)
However, if you are seeking some of the MAOIs and other alkaloids in tobacco, I would suggest supplementing with snus - you already know how your brain and body react to tobacco, after all.

robertpri: it's the other way around - without tobacco, your body's MAO enzymes (a kind of janitor for any excess serotonin, norepinephrine, and dopamine you have around) are probably back in action very quickly. (Gotta look this up, though. It's a guess based on the fact that tobacco's MAOIs lack the deadly food + drug interactions that you get with prescription MAOIs.)
The MAOIs sold as prescription antidepressants are the kind that bind irreversibly to the body's MAO enzymes, so when you stop taking those kinds of MAOIs, it takes your body two weeks to regenerate the free MAO.

I'm sorry to hear about your blood pressure - anxiety can absolutely worsen it - and about the emotional consequences you must still be feeling. You might want to try cutting your nicotine slowly, as it is a vasoconstrictor and therefore does raise your blood pressure. Exercise and lower salt intake are the big lifestyle fixes, but other means of stress reduction and self-expression might be really helpful in a very physical (BP) sense. I truly hope you find what works for you.
 
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thoqub

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You might want to read my post on St. John's Wort if you are considering it. (In it, I am mostly trying to point out that it is vastly different from Wellbutrin.) I am not saying SJW is a bad idea, but always talk to your doctor first, because it may interact negatively with other drugs you are taking.
It is much more like an SSRI than an MAOI. (Passionflower extract on the other hand is a mild MAOI.)
However, if you are seeking some of the MAOIs and other alkaloids in tobacco, I would suggest supplementing with snus - you already know how your brain and body react to tobacco, after all.

robertpri: it's the other way around - without tobacco, your body's MAO enzymes (a kind of janitor for any excess serotonin, norepinephrine, and dopamine you have around) are probably back in action very quickly. (Gotta look this up, though. It's a guess based on the fact that tobacco's MAOIs lack the deadly food + drug interactions that you get with prescription MAOIs.)
The MAOIs sold as prescription antidepressants are the kind that bind irreversibly to the body's MAO enzymes, so when you stop taking those kinds of MAOIs, it takes your body two weeks to regenerate the free MAO.

I'm sorry to hear about your blood pressure - anxiety can absolutely worsen it - and about the emotional consequences you must still be feeling. You might want to try cutting your nicotine slowly, as it is a vasoconstrictor and therefore does raise your blood pressure. Exercise and lower salt intake are the big lifestyle fixes, but other means of stress reduction and self-expression might be really helpful in a very physical (BP) sense. I truly hope you find what works for you.


thanks alot you can probably explain it better than me
 

robertpri

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robertpri: it's the other way around - without tobacco, your body's MAO enzymes (a kind of janitor for any excess serotonin, norepinephrine, and dopamine you have around) are probably back in action very quickly. [snip]

I'm sorry to hear about your blood pressure - anxiety can absolutely worsen it - and about the emotional consequences you must still be feeling. You might want to try cutting your nicotine slowly, as it is a vasoconstrictor and therefore does raise your blood pressure. Exercise and lower salt intake are the big lifestyle fixes, but other means of stress reduction and self-expression might be really helpful in a very physical (BP) sense. I truly hope you find what works for you.

Heh, just about the time I almost understood MAOI's. Oh well.

Yes, as we all know [but tend to forget at the worst possible times] anxiety is mostly self induced. 90% of what we fear never happens. In my case, make that 99%. I tend to worry about nonsense. Just can't help it. Genes, maybe?

I am pleased with my exercise efforts, nine consecutive days! [a record for me]

And all one can do about salt is try to reduce it. Damn stuff is in everything!
 

Madame Psychosis

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thanks alot you can probably explain it better than me
Heh, just about the time I almost understood MAOI's. Oh well.
Well...the more I learn about the brain and mood, the less I think I know. I do think MAOIs are fascinating stuff.
They're less known to the medical community nowadays because they've lost ground to the newer antidepressants (and, to be fair, MAOIs are riskier in terms of drug and food interactions, but some are safer than others). The remarkable thing about MAOIs is that they are some of the only antidepressants available that work directly to increase dopamine, which is the missing link for some forms of depression...and for some people trying to quit smoking.
Most of what's available out there right now for smoking cessation is just an end-run to shut up the nicotine addiction, or around one part of the antidepressant effect of tobacco (i.e. Wellbutrin...which does act on dopamine at higher doses, I think 300mg). So I do wish that medical research would give more attention to replacing the moderate MAOI effects that quitters are missing.

Side note on exercise: One way to get more walking I've found is my cheap treadmill+computer setup that I wrote a little bit about in another thread. I vape and surf and walk (and look ridiculous, no doubt ;)) and at least, it works well for me.
Even seems to reduce anxiety....after all, sometimes, with those awful spiraling thoughts that worries and guilt create, the best you can do is distract as much of your brain and body as possible. Exercise endorphins can't hurt, either.
 

robertpri

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River

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I'm pretty sure these things are way less addictive than analogs seeing as how after 2 hours without smoking tobacco my face felt like it was turning inside out and i would have killed somebody in front of their own mother just for one quick drag.

Now i can go all day without vaping and really not care one way or the other, i don't think i would be looking for additives to make them more addictive, who do you think you are? R.J. Reynolds??? Phil Morris??? :)
 
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