Another awful Prue Talbot study

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Placebo Effect

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E-Cigs Are Unsafe and Pose Health Risks

RIVERSIDE, Calif. – Electronic cigarettes (or e-cigarettes), also called “electronic nicotine delivery systems,” are increasingly used worldwide even though only sparse information is available on their health effects. In the United States, e-cigarettes are readily available in shopping malls in most states and on the Internet. But how safe are e-cigarettes?

To address this question, researchers at the University of California, Riverside evaluated five e-cigarette brands and found design flaws, lack of adequate labeling, and several concerns about quality control and health issues. They conclude that e-cigarettes are potentially harmful and urge regulators to consider removing e-cigarettes from the market until their safety is adequately evaluated.

Unlike conventional cigarettes, which burn tobacco, e-cigarettes vaporize nicotine, along with other compounds present in the cartridge, in the form of aerosol created by heating, but do not produce the thousands of chemicals and toxicants created by tobacco combustion. Nothing is known, however, about the chemicals present in the aerosolized vapors emanating from e-cigarettes.

“As a result, some people believe that e-cigarettes are a safe substitute for conventional cigarettes,” said Prue Talbot, the director of UC Riverside’s Stem Cell Center, whose lab led the research. “However, there are virtually no scientific studies on e-cigarettes and their safety. Our study – one of the first studies to evaluate e-cigarettes – shows that this product has many flaws, which could cause serious public health problems in the future if the flaws go uncorrected.”

Study results appear in this month’s issue of Tobacco Control.

Talbot, a professor of cell biology and neuroscience, was joined in the study by Anna Trtchounian, the first author of the research paper. Together, they examined the design, accuracy and clarity of labeling, nicotine content, leakiness, defective parts, disposal, errors in filling orders, instruction manual quality and advertizing for the following brands of e-cigarettes: njoy, Liberty Stix, Crown Seven (Hydro), Smoking Everywhere (Gold and Platinum) and VapCigs.

Their main observations are that:

* batteries, atomizers, cartridges, cartridge wrappers, packs and instruction manuals lack important information regarding e-cigarette content, use and essential warnings;
* E-cigarette cartridges leak, which could expose nicotine, an addictive and dangerous chemical, to children, adults, pets and the environment;
* Currently, there are no methods for proper disposal of e-cigarettes products and accessories, including cartridges, which could result in nicotine contamination from discarded cartridges entering water sources and soil, and adversely impacting the environment; and
* The manufacture, quality control, sales, and advertisement of e-cigarettes are unregulated.


The study was funded by a grant to Talbot from the University of California Tobacco-Related Disease Research Program (TRDRP).

“More research on e-cigarettes is crucially needed to protect the health of e-cigarette users and even those who do not use e-cigarettes,” said Kamlesh Asotra, a research administrator at UC TRDRP. “Contrary to the claims of the manufacturers and marketers of e-cigarettes being ‘safe,’ in fact, virtually nothing is known about the toxicity of the vapors generated by these e-cigarettes. Until we know any thing about the potential health risks of the toxins generated upon heating the nicotine-containing content of the e-cigarette cartridges, the ‘safety’ claims of the manufactureres are dubious at best.

“Justifiably, more information about the potential toxic and health effects of e-cigarette vapors is necessary before the public can have a definitive answer about the touted safety of e-cigarettes. Hopefully, in the near future, scientists can provide firm evidence for or against the claimed ‘safety’ of e-cigarettes as a nicotine-delivery tool.”

UC TRDRP supports research that focuses on the prevention, causes, and treatment of tobacco-related disease and the reduction of the human and economic costs of tobacco use in California.

About electronic cigarettes:

E-cigarettes consist of a battery, a charger, a power cord, an atomizer, and a cartridge containing nicotine and propylene glycol. When a smoker draws air through an e-cigarette, an airflow sensor activates the battery that turns the tip of the cigarette red to simulate smoking and heats the atomizer to vaporize the propylene glycol and nicotine. Upon inhalation, the aerosol vapor delivers a dose of nicotine into the lungs of the smoker, after which, residual aerosol is exhaled into the environment.

Question: Does anyone know if the diluted nicotine present in e-cigs can harm a person through skin contact? And how diluted is the nicotine?

I left a message on Dr. Asotra's machine telling him I was disappointed in his statement, and feel that he knew what conclusion he was going to reach going in. That number is 510-987-9537.

The author of the research paper, Anna Trtchounian, can be reached at 818-744-2100 and Anna.Trtchounian@gmail.com. I spoke to Ms. Trtchounian earlier today, expressed my displeasure, asked her if she knew from the very start if the conclusion of the article was going to be negative (she said no), and she kindly told me she'd call me back earlier

The contact info was retrieved from the first couple hits for these person's names on Google.
 
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Placebo Effect

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Sorry about that -- http: //newsroom .ucr.edu/news_item.html?action=page&id=2506
[rebuild link by removing spaces in URL]

And from researching I found that Ms. Trtchounian was also partially responsible for the humorous anti-e-cig study that damned them because users have to take stronger inhales at the end of a cartridge.
 
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Petrodus

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This is a "Piece of Work"

It has the appearance of a summary of a "Formal Scientific Study" by a well known University
but it doesn't have any real "meat on the bone"

To me...It's nothing but Propaganda and "Controlled Confusion"

Propaganda...The Title
Controlled Confusion: The Content

Here is a page on the subject of "Confusion"
Warning Reading this page will give you a headache: Click Here

Controlled Confusion
 

Tom09

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t9c

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E-cigarettes consist of a battery, a charger, a power cord, an atomizer, and a cartridge containing nicotine and propylene glycol. When a smoker draws air through an e-cigarette, an airflow sensor activates the battery that turns the tip of the cigarette red to simulate smoking and heats the atomizer to vaporize the propylene glycol and nicotine. Upon inhalation, the aerosol vapor delivers a dose of nicotine into the lungs of the smoker, after which, residual aerosol is exhaled into the environment.

This statement needs some (a lot of) qualification to which the Health NZ Study provided years ago:

Inhaled nicotine in cigarette smoke is over 98% absorbed 6, and so the
exhaled mist of the e-cigarette is composed of propylene glycol, and probably contains
almost no nicotine; and no CO. (see Figure 3.5) Lacking any active ingredient or any
gaseous products of combustion, the PG mist or ‘smoke’ is not harmful to bystanders.
The ‘smoke’ or mist is not tobacco smoke, and not from combustion – no flame is lit –
and is not defined as environmental tobacco smoke. E-cigarette “smoking” would be
permitted under New Zealand’s Smoke-free Environments Act 1990.

Once again, it's nicotine that is the bad guy in this yet another ridiculous study.
 

Vocalek

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This statement needs some (a lot of) qualification to which the Health NZ Study provided years ago:


Once again, it's nicotine that is the bad guy in this yet another ridiculous study.

I emailed Dr. Asotra, providing links to both the HNZ Safety Report on the Ruyan E-cigarette and to the Dublin SRNT poster and quotes from each.

http://www.healthnz.co.nz/RuyanCartridgeReport30-Oct-08.pdf
http://www.healthnz.co.nz/DublinEcigBenchtopHandout.pdf

I also provided a link to the Study to Determine Presence of TSNAs in NJOY Vapor http://www.casaa.org/files/Study_TSNAs_in_NJOY_Vapor.pdf

Finally, I suggested that if the worry was whether there were toxic ingredients in the vapor, I find it difficult to understand why TRDP funded a study conducted by a cell biologist regarding the engineering quality of electronic cigarettes. Why not fund an air quality expert and/or a toxicologist to look for toxicants in the vapor from e-cigarettes?

"Better yet, why not survey electronic cigarette consumers who have been using the products to let you know what the effects have been on their health and on the health of those around them? Give me a call and I would be happy to share my story with you."

I provided my phone number. I am waiting with baited breath for Dr. Asotra's call.
 

kristin

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This is one of the few places I found that allows comments p it's the University of California web site:

http: //universityofcalifornia .edu/sites/uchealth/2010/12/03/study-e-cigarettes-are-unsafe-pose-health-risks
[rebuild link by removing spaces in URL]

Study: E-cigarettes are unsafe & pose health risks.|.UC Health
 
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rothenbj

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"Finally, I suggested that if the worry was whether there were toxic ingredients in the vapor, I find it difficult to understand why TRDP funded a study conducted by a cell biologist regarding the engineering quality of electronic cigarettes. Why not fund an air quality expert and/or a toxicologist to look for toxicants in the vapor from e-cigarettes? "

Elaine, neither an air quality expert or a toxicologist would have been qualified to perform this study based on the conclusions that were required to enable the study to be performed. Starts looking a lot like what we've seen on second hand smoke.

Pretty soon expect to hear or read about the BODY OF EVIDENCE THAT "ENDS" ARE NOT A SAFE ALTERNATIVE TO SMOKING. The hint in the press release comes with the use of “electronic nicotine delivery systems” as a synonym for E Cigs. None of the users consider it as such as most would consider it as a personal vaporizer. WHO was very careful in redefining it to a name that would fit with their desire to move the profits to their benefactor.
 

lonercom

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E-Cigs Are Unsafe and Pose Health Risks

Question: Does anyone know if the diluted nicotine present in e-cigs can harm a person through skin contact? And how diluted is the nicotine?

I wrote about this in my first post at The Lone Fogger

I mentioned that pure nicotine can be fatal so I did some digging: The fatal dose appears to be .5 to 1 mg/kg. For those of us a little shaky with metric, that would be 1mg per 2.2lb. For me, weighing 260lb that would be 286 to 572mg consumed in one sitting. For a 6 year old weighing 45lb that would be 49 to 100mg. Out of curiosity, and thanks to my good friend, Google, I found out that the lethal dose of pure caffeine is 150 to 200 mg/kg. (or 2.2lb) For my 260lb frame, that would be 85850 to 114422mg of caffeine. I’d still keep E-Juice and paraphernalia out of the reach of kids. While it may not be enough to kill them, it’s plenty to make them VERY VERY SICK.
 

Petrodus

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Unfortunately for us this study is being copied and pasted on tons of web pages
and spreading fast on the Net

University of California, Riverside (news release):
http: //newsroom .ucr.edu/news_item.html?action=page&id=2506

Google: "Electronic Cigarettes Are Unsafe and Pose Health Risks"
www .google .com/search?q=%22Electronic+Cigarettes+Are+Unsafe+and+Pose+Health+Risks%22&hl=en&num=10&lr=&ft=i&cr=&safe=images

I'm starting wonder who initially suggested the University conduct this study.
Recently the gap between being a conspiracy theorist and a realist is narrowing!
 
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vappoem

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Yeah... I read this "study" and am still trying to figure out what was "studied." Nicotine may cause environmental damage? Unknown toxicity? I'm sorry and I mean no disrespect to the woman, but she didn't study anything. Instead it seems that she looked at the product and played a theoretical game of "what can go wrong." I am so tired of these studies. E cigarettes deserve a fair, non-bias study. I realize that a true scientific study can not rely on personal account, but it seems to me that with all the success stories published here and elsewhere, one scientist would at least be willing to really test the product and really look at what is right/wrong with e-cigarettes. I'm tired of reading these half done reports that don't address the central issue: Are e-cigarettes,in theory, a healthier alternative to cigarettes? Why can't anyone just address that issue head on? Instead we get theoretical ramblings, unqualified claims that the e-cigarette industry is a backdoor for big tobacco, and the constant claim that every supplier is trying to hook three year old kids to nicotine, because they offer a flavor other than tobacco. I guess such is the reasoning process in the "wikipedia" age... Oh well, if you read this post, thanks for letting me vent. Now, I'll go and vape. Before I do, perhaps I could address some issues. 1) Write clearer instructions for E-cigarettes, including instruction for use and contents 2) Warn people that they shouldn't let their cats and children drink e-liquid 3) Offer recycling programs for used e cigarettes, including liquid and batteries 4) Start working with e-liquid manufactures in-order to ensure a fair and safe manufacturing process, instead of threatening a ban...
 

AlmightyGod

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This is one of the few places I found that allows comments p it's the University of California web site: Study: E-cigarettes are unsafe & pose health risks.|.UC Health

I gave them my 2 cents...thanks for the link!
 
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