Thanks for the update, JoAnna! Another very interesting result. Just when I thought that one has to vape intensively xx-high to max-out the test... So, this was achieved with medium-high liquid vaping? Could you add some estimate on your mileage? May not have been the same amount of cotinine (the proxy for delivered nicotine) from vaping and analogs, since highest test level is anything above the cutoff (> 1000 ng/ml). But certainly appears to be effective vaping.
Seems there can be much variation for different individuals. Just compare some graph, randomly picked from a scientific study, showing smoking habit and cotinine in urine concentrations [ng/ml] of 128 test subjects. Graph for illustration, not meant to be authoritative, here. While there is a dose dependence for the average, not everyone is the average, as reflected by the large error bars. Damn, I really thought this would turn out to be simple!
Source: Ziegler et al. (2004): Clinical Correlation between the Consumption of Nicotine and Cotinine Concentrations etc., Pharmacology 72:254259.
Im by no means an expert in biology or medicine. I just find the question of actual nicotine delivery from vaping personally interesting and highly important. And while we keep speculating, Id certainly prefer to read some professional experts informed opinion... But looking from my laymens perspective, I think that all results from the home tests (as gratefully posted by Minimike, Kate51, JoAnna1010) are (1.) internally consistent and (2.) do support the prevailing notion from user experiences and the first reports of the Laugesen/Ruyan-team, suggesting that vaping is significantly less effective for nicotine delivery than analog smoking.
It has to be noted that the Nymox home test appears to come with a relatively low cutoff (equivalent to 1000 ng/ml cotinine in urine, according to the simplistic product flyers). Most moderate smokers of 10-19 cigarettes per day would score the highest level, score above the 1000 ng/ml cutoff (see the illustrating graph above). Moreover, reading from this illustrating graph, even some occasional to light smokers would score above this cutoff. Just dont bash JoAnna for her personal body functions, individually different for every one
.
Nevertheless, a value of 200-500 ng/ml reported from someone (Kate51) who - by all means - reported constantly vaping 24 mg strength (and so Id guess runs > 2 ml/day)
IS a bench. There is not much chance that a one-pack-a-day smoker would return such a low cotinine level. But certainly, more testing and professional, better informed opinions are needed.
.... don't think so.
