I can sit the freaking thing down now!!!

[larrball]

After 4+ months of vaping (call me a dumb @$$ if you want, I don't care)

No i never would, not for my first post.

 

[natura]

Upon reading wireguy's first post in this thread, made me want to pay attention to him. Because FDA and all the other concern's on MAJOR threads of REAL Information that should be of prime importance to ALL who love PV's.

You toook what he said as a personal dig. I do not believe that was the case at all.

Some here are sensitive to information imparted as facts (which you eluded to) and he wanted it corrected. Misinformation can shut this business down.8-o I look at the recent slogan thread for v4l winners and say to myself... so sad..they too don't get it either.


BTW I do not know either of you. I am impartial.

 

[DcMagic]

Maybe its just me...
But I have a stock 510..and I can smoke 36mg PG nic juice ALLL DAY LONG....and not feel a damn thing....I actually wanted to move to a higher nic amount...

 

[Madame Psychosis]

There must be something seriously wrong with those of us who chain vape 36mg+ and feel fine for the most part

Aside from the whole stimulant-tolerance thing, you might just have a liver that is, like your Chuck, customized for nicotine intake:

Nicotine is metabolized, like many drugs, by the cytochrome-P450 liver enzymes, and there are many genetic polymorphisms governing how fast you metabolize through each enzyme. Some people are "cheap dates", i.e. they have very little of an enzyme and therefore a lot more of the original drug stays in their bloodstream for longer. Others are so-called rapid or ultrarapid metabolizers through an enzyme and their liver converts a drug to its metabolites very quickly.
So, if you have a polymorphism that makes you a more rapid metabolizer through CYP2A6 or CYP2B6, the main enzymes breaking nicotine down into cotinine, your liver might be going through that nicotine like a blast furnace.
(I am not a doctor, just a patient and a geek since I was a wee one. This is pretty much speculation ported from knowledge of how other drugs/enzymes work.)

 

[VapingRulz]

There must be something seriously wrong with those of us who chain vape 36mg+ and feel fine for the most part

I hope not. I have no problems at all with the 36mg. I'm decreasing it as part of a calculated plan to get to zero nicotine eventually...not because it bothers me at all. (I like 36mg!) Some of us obviously have a much higher nicotine tolerance level than others. It's interesting because there doesn't seem to be much direct correlation between former smoking habits and current nic e-juice levels.

It seems like plenty of former 2-pack-a-day smokers are doing well with low nic levels (18mg and lower), and many formerly light smokers and/or smokers of light brands of cigarettes need higher nic levels to stay off the analogs.

It doesn't make any sense.

 

[316lvm]

@Karl and 86d -
Thanks for your responses. Never got a tight feeling in the chest until this past 2 weeks. Still trying to find my level. Inadvertently gave myself a 42mg quick fix - was vapping 24mg and topped off with 18mg instead of zero.

Now I know what getting tazed feels like but without the pain

 

[quasimod]

[...]Inadvertently gave myself a 42mg quick fix - was vapping 24mg and topped off with 18mg instead of zero.[...]

Maybe I'm misunderstanding you, but that sounds like it would be some random nic strength between 18 and 24MG. A 50/50 mix of 18 and 24 would give you 21MG, right?

 

[Birdy]

Maybe I'm misunderstanding you, but that sounds like it would be some random nic strength between 18 and 24MG. A 50/50 mix of 18 and 24 would give you 21MG, right?

yup, 21mg.

wondering if the problem for 316lvm isn't all the ups and downs in nic all day from "topping off" with a different strength.
It would be like smoking 100's for a few hours, then an ultra light, then a few filterless, etc.
Gah, that's would be enough to make me feel like crap.

 

[Madame Psychosis]

I hope not. I have no problems at all with the 36mg. I'm decreasing it as part of a calculated plan to get to zero nicotine eventually...not because it bothers me at all. (I like 36mg!) Some of us obviously have a much higher nicotine tolerance level than others. It's interesting because there doesn't seem to be much direct correlation between former smoking habits and current nic e-juice levels.

It seems like plenty of former 2-pack-a-day smokers are doing well with low nic levels (18mg and lower), and many formerly light smokers and/or smokers of light brands of cigarettes need higher nic levels to stay off the analogs.

It doesn't make any sense.

It can make sense if you consider three other significant variables we don't often know:

* Vaping behavior (how long we're holding in the vapor, how accurate our estimates of mLs used are)

* Previous smoking behavior (it's proven that drag length/smoke held in the lungs/other behavior variables influence nic intake a LOT in smoking)

* The extent to which nicotine was the real focus of our previous addiction (as opposed to other alkaloids and the hand-to-mouth behavior)

 

[the86d]

lvm - Logical Volume Manager? Or the metal?

 

[the86d]

Yup I was right on with my DIY estimate.

I just (yes at about 1:30am because I had it shipped to the new address I will be moving to & @10Mi each way, because I couldn't sleep) received some 11mg juice from a closeout special. I HAVE TO sit the thing down.

This is about perfect for me.