I would really like to see the data on this study, effect size, if the people who developed "slightly increased number of [...] serious heart-related events was actually significant in relation to the sample. 350 doesn't seem terribly small to me, considering a sample size of 30, comes quite close to being a representative sample. I feel like they're downplaying it, this stuff might kill you, but it's better than smoking. We'll worry about the heart thing, once we can find more trace elements in e-cigs