The Pico acts like a mech (battery voltage), but does have protections such as atomizer short, battery cutoff, etc. As long as you've got a quality cell in it and pay attention to the build resistance, probably not much to worry about.
It seems to state it has a 50w limit as well, but I've read where folks compare it to a mech and claim there is no 50w limit, all depends on your build. Maybe folks that are more familiar with it could comment.
I picked up a pair of them (around $16 on FT), but haven't fired them up yet. I would have no problems with them though as long as you know you have a build that is well within the limits of your battery.
They look like they will be great little drop in the pocket mods when you're ducking out of the house for a bit. I like the pico 75 for a stealth vape and once I started squonking, figured it was a no-brainer. Everyone should have at least one, or two, lol.
I'm planning on running mine with a Wasp Nano most likely, but I've come to really enjoy the Nudge 22 lately.