The OP linked to Dr Farsalinos' study on nicotine absorption from electronic cigarette use that does a pretty good job of comparing the blood plasma levels achieved by the user of first and second generation e-cigarettes versus tobacco cigarettes:
"The results of the study showed that nicotine absorption from e-cigarettes was significantly lower compared to tobacco cigarettes. In reality, 5 minutes of use led to 1/3rd to 1/4th plasma nicotine levels compared to smoking 1 tobacco cigarette. "
I understand that, but if I sit a group of kids at a table and pass out plates of ice cream and plates of liver and onions, then tell them to eat for five minutes … the results aren't going to be good if your using that method to determine how much energy in the form of calories can be gained from liver in a five minute span.
A better method, in my opinion would be to use a mechanical device to assess maximum nicotine content of both vapor and smoke, normalize the quantity provided the test subjects (let's say a quantity of both smokes and juice that at best is delivering 10mg of nicotine), then test for absorbed nicotine at equal intervals until the smokes and juice are completely expended.
If that test were done with enough people you would have a better understanding of how similar or different vapor delivered nicotine is absorbed vs smoke delivered nicotine.
I might draw a different conclusion from the vaping vs smoking for five minutes test that found lower nicotine levels in the vapers, and that is that the vaping group is not able to consume nicotine at a rate equal to the smoking group with the devices used.
However if in a test such as the one I described above test subjects found to vape and smoke their allotted measure of tobacco and juice in a similar time frame were identified, we could do a more accurate assessment of the two methods of nicotine delivery.
It seems to me a more 'candied apples to candied apples' comparison than anything else.
Maurice