Sucralose - toxic/carcinogen forming when heated

[DrMA]

http://www.splendaprofessional.com/sites/default/files/common/Sucralose_Study.pdf

Looks pretty conclusive to me , though they do not address thermal decomposition byproducts.

Here's a few examples:
http://www.sciencedirect.com/science/article/pii/S0308814609005378
http://www.scielo.br/scielo.php?pid=S0100-46702009000400002&script=sci_arttext
http://www.nature.com/srep/2013/131015/srep02946/full/srep02946.html

Read and draw your own conclusions. But to me it looks like you need to heat the cr@p out of pure sucralose in the presence of fancy catatlysts to generate any notable amount of polychlorinated dioxin-like compounds. We're talking 660-840°F here people - not likely to occur in normal vaping.

 

[DigitalKnight]

For those that didn't pick up on it, dihydrogen monoxide, chemical formula H2O, is actually water. And by putting it in the same post as the sucralose comment, I was indeed equating the scientific merit of both controversies, IMO.

As for the aspartame studies with cell cultures: gotta be careful with the interpretation of those, as they test unrealistic exposure conditions. Do you know what happens if you expose cell cultures to dihydrogen monoxide? The cells balloon up and burst . Does that mean that drinking water is going to make you explode?

That's why I posted Genotoxicity testing of low-calorie sweete... [Drug Chem Toxicol. 2008] - PubMed - NCBI separately. The mice were orally given doses. The average person consumes about 5mg/kg of aspartame a day and the lowest dose given to the mice was 7mg/kg, and the mice still show signs of the adverse affects. The study concluded "These findings are important, since they represent a potential health risk associated with the exposure to these agents."

 

[Sdh]

That's why I posted Genotoxicity testing of low-calorie sweete... [Drug Chem Toxicol. 2008] - PubMed - NCBI separately. The mice were orally given doses. The average person consumes about 5mg/kg of aspartame a day and the lowest dose given to the mice was 7mg/kg, and the mice still show signs of the adverse affects. The study concluded "These findings are important, since they represent a potential health risk associated with the exposure to these agents."

I thought this was a Splenda/sucrolose scare thread...Aspartame (Trade name is Nutrasweet) is totally different.


I don't care for nutrasweet. I do use Sucrolose but not the stuff you buy at the store.

 

[Traver]

Here we go with the "aspartame controversy" all over again, this time applied to sucralose. Before you put on your tin foil hat and start living off the grid, read what the risks of dihydrogen monoxide are and weigh them against those of sucralose. Most e-liquid contains about 10% dihydrogen monoxide, which is a known contaminant of both PG and VG from the manufacturing process.

When it comes to dihydrogen monoxide I am a daredevil and drink it with impunity. Not sure what that has to do with anything else.

 

[ColinD]

Thanks for all the very useful input here guys. I believe the overriding factor is that now we are off the ciggies we do have choices in the juice we either buy or make ourselves. So if we are personally worried about contents like sucralose there are alternatives unlike with the stinkies. There is no harm in taking into account the 'possible' harm of certain ejuice contents and acting in whatever way we wish. All hail the vaping community.

For me - no more sucralose. As you know our body chemistry is individual and I have a choice not to use sucralose so I won't.

 

[ukeman]

when i saw the word "heated" sucralose of course a bell went off in my head.
Perhaps we don't heat it to the extent harmful… that would be great.
I am getting more and more into DIY, and I will aim my inquiries about ingredients in flavorings…I've tried some flavorings from TFA which is known for having lots of natural flavorings… some of them are damn sweet.

Nobody is saying not to vape btw… and the article by Mercola was not an anti vaping article.
DIY is a good way to keep things simple, without sacrificing good vaping, you can control your ingredients (minimize harm).

 

[WarHawk-AVG]

ERMAHGERD...might cause miniscule carcinogenic amounts if heated too hot

Go find out just how much tar and Carbon Monoxide you get EVERY cig..no matter what...then find out what it does to the human body, then realize NONE of that is in personal vaping juice

Oh wait...I already did

http://www.e-cigarette-forum.com/fo...-its-not-nicotine.html?highlight=the+nicotine