* Tobacco Withdrawal * - Anxiety and Depression sufferers

[peterb107]

I don`t think reading these types of things help me.......BUT at least it prepares me!

Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms.
Rose JE1, Behm FM, Ramsey C, Ritchie JC Jr.
Author information
Abstract

Previous studies have found that constituents in tobacco inhibit both forms of the enzyme monoamine oxidase (MAO-A and MAO-B). This enzyme is important in the breakdown of the amine neurotransmitters, including dopamine, which is thought to mediate the reinforcing effects of nicotine and contribute to tobacco dependence. To further examine the relationship between cigarette smoking, smoking cessation and MAO, we measured platelet MAO-B activity in 16 smokers before and after being switched to smoking denicotinized cigarettes; in a subset of six subjects who subsequently quit-smoking, MAO-B activity was also measured at 1 and 4 weeks following cessation. Smoking cessation treatment was provided in an open-label format, and included nicotine skin patch treatment in conjunction with oral mecamylamine (a nicotinic antagonist) and neostigmine (a peripherally acting acetylcholinesterase inhibitor, administered to counteract constipation experienced from mecamylamine). Results showed that smoking behavior, indexed by expired air carbon monoxide levels, was negatively correlated with platelet MAO-B activity prior to smoking cessation. Moreover, MAO-B activity significantly increased by approximately 100% at 4 weeks after quitting smoking. However, little or no recovery occurred within the first week of abstinence, suggesting that the constituents in tobacco responsible for MAO inhibition may have half-lives of several days. Thus, if relapse to smoking is due in part to withdrawal from the MAO-inhibiting effects of tobacco, this effect likely occurs more than 1 week after quitting. Additionally, low baseline MAO-B activity significantly predicted the intensity of withdrawal symptoms reported upon switching to the denicotinized cigarettes as well as after smoking cessation. These results support the view that MAO inhibition from non-nicotine constituents in cigarette smoke is relevant to tobacco dependence and that continued investigation of the potential use of MAO inhibitors in smoking cessation treatment is warranted.

So I guess, if it`s coming (withdrawal/anxiety/depression).....it will be another day or two before it hits me!

 

[djsvapour]

I don`t think reading these types of things help me.......BUT at least it prepares me!

You'll be OK.

(You really will....)

 

[peterb107]

Hoping so!!

Just to update

Day 5 afternoon-evening

Very calm feeling, but very "stuck in my head" and little concentration with whats going on around me.

No more thoughts of a cheeky ... at all for the rest of the day though

That`s about 100 I haven`t smoked now......


.....How much juice are you guys smoking per day?

As stated, I`m on 18mg and probably doing about 1.2 ml of juice a day..... too much? too little??

 

[Renolizzie]

That's the spirit, it's the ones you don't smoke that count!

You are doing great! PeterB.

Keep going.

 

[skoony]

there is no help for you.people diagnosed with anxiety can not be codified.
its as if they to the one have different things that set them off.they prefer it this way
so than can freak out at a moments notice.usually to make one uncomfortable.
my advice to you is to buck up and quit bothering people with your ama approved reason to get
prescription drugs.don't forget to be shy.
regards,
mike

 

[peterb107]

there is no help for you.people diagnosed with anxiety can not be codified.
its as if they to the one have different things that set them off.they prefer it this way
so than can freak out at a moments notice.usually to make one uncomfortable.
my advice to you is to buck up and quit bothering people with your ama approved reason to get
prescription drugs.don't forget to be shy.
regards,
mike

Obviously you have never suffered with Anxiety or depression..... they`re REAL illnesses, not fleeting moments of feeling sad or a little paranoid.

I don`t expect you to be able to comprehend the level of suffering some of us have to go through each day if you have never experienced it yourself.

So my advise to you is..... buck up, and stop butting in on conversations you know bugger all about.

And if you`d actually read my posts....you`d see that I have NEVER taken a prescription med for my "issues" in my life.

The title reads - Tobacco withdrawal for Anxiety and Depression sufferers......If you have nothing positive to add to it, then please ignore the conversation rather than offend people with your narrow minded views

 

[Renolizzie]

there is no help for you.people diagnosed with anxiety can not be codified.
its as if they to the one have different things that set them off.they prefer it this way
so than can freak out at a moments notice.usually to make one uncomfortable.
my advice to you is to buck up and quit bothering people with your ama approved reason to get
prescription drugs.don't forget to be shy.
regards,
mike

Really, that wasn't nice, Mike. When did Americans become such judgmental know-it-alls that have nothing nice to say and who must .... in even when it doesn't concern them nor affect them in the least?

Good job sticking up for yourself, PeterB.

 

[ovshell]

I too suffer from anxiety and depression. I find these experiences and suggestions very helpful. Thanks!

Sent from my Xoom using Tapatalk

 

[etchie]

I have anxiety as well and I didn't experience any major problems. It differs with everyone though.

 

[NC_Fog]

Just a couple of thoughts...1.2ml of 18mg seems kinda low for someone just switching from smoking to vaping.
Maybe try some 24mg for awhile until you are settled into vaping.

One of the biggest things that helped me is that I made up my mind that I wasn't going to pressure myself. When I started I didn't really crave a cigarette, however it did take a couple of weeks for me to settle in. I started at 18mg the first couple of days but something wasn't quite right. I moved up to 24mg where I remained for about two weeks. Then back to the 18mg and all was well. We are all different, so try different ways until you find one that suits you for the moment. Your body is in shock right now...lol.

Good Luck!!!

 

[skoony]

Obviously you have never suffered with Anxiety or depression..... they`re REAL illnesses, not fleeting moments of feeling sad or a little paranoid.

I don`t expect you to be able to comprehend the level of suffering some of us have to go through each day if you have never experienced it yourself.

So my advise to you is..... buck up, and stop butting in on conversations you know bugger all about.

And if you`d actually read my posts....you`d see that I have NEVER taken a prescription med for my "issues" in my life.

The title reads - Tobacco withdrawal for Anxiety and Depression sufferers......If you have nothing positive to add to it, then please ignore the conversation rather than offend people with your narrow minded views

sorry,i was trying to be a little tongue in cheek there.
however i am beginning to think that there are a higher percentage of hypochondriacs in the vaping community
than the average population.
by the way my views are not narrow minded.
"people make up there minds to be as happy as they want to be"Abraham Lincoln.

regards
mike

 

[3mg Meniere]

however i am beginning to think that there are a higher percentage of hypochondriacs in the vaping community than the average population.
mike

Guilt over having abused our bodies in the past?

 

[dshgr]

Mike,

I hope you are never diagnosed with any chronic mental or physical illness. What you are saying amounts to telling a diabetic that they don't need insulin.

Are you a Scientologist by chance?

Perhaps you should keep your narrow-minded opinions to yourself.

 

[AndriaD]

Welcome, peterb! Hope you're hanging in, and hanging tough, and nevermind idiots who know nothing whatever about mental/emotional disorders.

I've dealt with depression and anxiety my whole life, so I can completely empathize, and it's true that quitting smoking can be bumpy for those of us who suffer this type of problem, but it's not impossible, if it's what you *really want* -- that seems to be the most important ingredient of quitting successfully, if you really want it rather than feeling pressured into it.

Since you're past 3 days smoke-free, you've already navigated the first bump -- there is an axiom about the 3 most troublesome spots -- 3 days, 3 weeks, and 3 months -- all those seem to mark some chemical(s) leaving a quitter's body, probably those MAOIs, which may bring on some really negative feelings. Between 2.5 and 3.5 wks, I hated the world and everything and everybody in it -- getting some shiny vapemail helped, and just sticking to my "guns" about quitting -- truthfully I'm tickled pink about being ABLE to finally quit with so little suffering.

Right now I'm at 90 days, and I noticed last night I was having some of those same feelings, just mad at everybody about everything. Later on I got a little better, and today seems better too -- I've finally reached the time-frame of quitting that I reached just once before, cold-turkey 30 yrs ago, but that time, I was so wretched every minute, I couldn't stand it anymore and just had to go back to smoking. This time, I'm not wretched, I'm finally freed from smokers' prison, and that is such a wonderful thing, it's hard to sustain a really negative attitude for very long.

Just hang tough, and keep an eye on how you're feeling, and realize that most of us go thru similar things, even those with no previous history of anxiety/depression -- they get to enjoy what we've enjoyed for so long! It does pass, and far more quickly than you would think feelings of this type could ever pass, because it's not real, it's not YOU, it's just some chemicals leaving your body. If it gets to the point that you can't take it anymore, then by all means, see a doc and maybe get some medication that's a lot better for you than tobacco-provided MAOIs. And by all means, pay no attention to the ignorant who think we can just snap our fingers and "snap out of it!" It's very much like diabetes or asthma, a real physical disorder (of the neurotransmitters in the brain), and it's just as impossible to "get over it" as diabetes or asthma; medication can help you deal, can help you get past the worst of it, and it's possible to learn better coping skills, and also to learn how to simply live with it, knowing that you'll always be prone to those kinds of feelings. If they become more than you can handle, don't smoke, go to a doctor and get some REAL medication.

Hang tough! Ignore idiots! VAPE ON!!
Andria

 

[skoony]

Mike,

I hope you are never diagnosed with any chronic mental or physical illness. What you are saying amounts to telling a diabetic that they don't need insulin.

Are you a Scientologist by chance?

Perhaps you should keep your narrow-minded opinions to yourself.

no i am not a scientologist.
excuse me for being insensitive as i am well aware depression can be a very debilitating condition.
i am also aware its the number one reason to get legal drugs and a free ride from the government if you are so inclined.

Astounding increase in antidepressant use by Americans - Harvard Health Blog - Harvard Health Publications
https://www.apa.org/monitor/2012/06/prescribing.aspx
Antidepressant use soars, study says: Is depression overdiagnosed? - CBS News
The Epidemic of Mental Illness: Why? by Marcia Angell | The New York Review of Books
like with ADHD i can see two sides to this story.
i have no problem standing by my previous post.

regards
mike

 

[3mg Meniere]

We are talking about biochemical problems on this thread. It is not about medicating people so that they can accept problems in our society.

 

[Renolizzie]

no i am not a scientologist.
excuse me for being insensitive as i am well aware depression can be a very debilitating condition.
i am also aware its the number one reason to get legal drugs and a free ride from the government if you are so inclined.

Astounding increase in antidepressant use by Americans - Harvard Health Blog - Harvard Health Publications
https://www.apa.org/monitor/2012/06/prescribing.aspx
Antidepressant use soars, study says: Is depression overdiagnosed? - CBS News
The Epidemic of Mental Illness: Why? by Marcia Angell | The New York Review of Books
like with ADHD i can see two sides to this story.
i have no problem standing by my previous post.

regards
mike

Mike - The people on this forum tend to be supportive of one another. This is personal situation not a broader societal problem for PeterB. Think about it. Philosophically speaking, some depression and anxiety is expected in humans. We face situations and problems and we try to deal with them. For many people, depression is a situation to be dealt with. You don't know anything about PeterB nor myself, really.

Did you know that I have faced an incredible amount of trials in my life. I am not on medications of any sort nor do I want to be. Cigarettes has certainly been a way for me to cope. The problems with the medical system in our country really have nothing to do with my personal situation nor does it have any bearing on PeterB's personal situation. What PeterB needs is some kindness a support from people who get what he is going through. IMHO

 

[skoony]

Mike - The people on this forum tend to be supportive of one another. This is personal situation not a broader societal problem for PeterB. Think about it. Philosophically speaking, some depression and anxiety is expected in humans. We face situations and problems and we try to deal with them. For many people, depression is a situation to be dealt with. You don't know anything about PeterB nor myself, really.

Did you know that I have faced an incredible amount of trials in my life. I am not on medications of any sort nor do I want to be. Cigarettes has certainly been a way for me to cope. The problems with the medical system in our country really have nothing to do with my personal situation nor does it have any bearing on PeterB's personal situation. What PeterB needs is some kindness a support from people who get what he is going through. IMHO

shouldn't peterb be posting on a medical forum then.no offence to peterb.
i hope he does well.he should be consulting with his doctor about his anxiety.
regards
mike

 

[peterb107]

Thanks for some really inspiring and thoughtful replies.

Mike...... I have dealt with AND conquered bouts of severe depression and debilitating anxiety my whole life - WITHOUT medication.

But all that while, I had continued smoking.

Since smoking contains MAO`s (anti-depressants).....and I`m no longer going to be getting those anti-depressants - I`m worried that the sudden withdrawal of these chemicals could re-trigger....well.....hell, basically.

Anyway.... to update on today - I`ve actually felt a lot more normal and "with it", still not 100%, but for my body to suddenly be denied the 4000 chemicals it has been fed, 15 times a day for the past 20 years.......maybe this feeling is justified and expected!

Again, thanks for the support and helpful posts, all.

 

[peterb107]

sorry,i was trying to be a little tongue in cheek there.
however i am beginning to think that there are a higher percentage of hypochondriacs in the vaping community
than the average population.
by the way my views are not narrow minded.
"people make up there minds to be as happy as they want to be"Abraham Lincoln.


Biggest load of bull I have ever read!
regards
mike

Biggest load of bull I have ever read!