UKNSCC June conference

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rolygate

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A little late with this one, but thanks to those who linked to it on FB.

UKNSCC - UK National Smoking Cessation Conference
June 2012, Birmingham UK
UKNSCC - UK National Smoking Cessation Conference


Dr Hayden McRobbie's presentation on electronic cigarettes

Dr McRobbie gave a good presentation on e-cigarettes to this medical conference on smoking cessation in Birmingham, UK in June. He works in NZ and the UK, and may have been involved with Bullen and others (Laugesen? not mentioned though) in the early NZ tests on a Ruyan product in 2006.

He correctly identified that experienced users upgrade to models that perform better than the widely-available entry-level models. He repeated the advice that, "The less it looks like a cigarette, the better the performance will be".

As a medic, in the tobacco control area, he is unusually sympathetic to e-cigarettes, though perhaps not up to date with developments since the early years. In order to provide this medical conference presentation he reports that he had to research the subject on the internet. However, he does have much more knowledge of the subject than most people declaiming on it who researched it on the web. There are some rough edges here that are occasionally amusing, such as the reference to ecig users as 'vappers' (rhyming with rappers).

As a consequence perhaps, there is too much mention of 'smoking' an e-cigarette. They can't be smoked as there is no smoke. If someone were to breathe in steam from a kettle, could it be described as smoking? The product supplies a water-based vapour and therefore can be described as 'being used' or 'using an ecig' or 'vaping' or 'being vaped' - but not 'smoked'. There is no tobacco, no ignition, no combustion and no smoke. A PV can be 'smoked' about as much as Snus can be smoked.

The statement, from surveys, that "People believe that e-cigarettes are less harmful than smoking" - this may be true, but on the other hand current medical opinion is that ecigs are less harmful than smoking, so perhaps this should be mentioned. Even the MHRA have admitted this.

The lipoid pneumonia issue is mentioned, and perhaps some medic somewhere should consult the expert vapers on this. We are well aware that there is likely to be an increase of risk for emphysema sufferers since they are at increased risk for pneumonia, therefore Stage 4 COPD / emphysema patients should NOT use e-cigarettes. Patients with early COPD should only use e-cigarettes with close supervision by their thoracic consultant. As regards lipoid pneumonia vs pneumonia, we would want to see a great deal of pathology on the precise disease implicated and absolute proof that lipoid pneumonia is involved, since this would be the first case recorded where glycerine has been shown to cause a disease normally associated with paraffin. It would be of great importance to the pharmaceutical industry since glycerine is now the preferred excipient for inhalable medicines and is very widely used for this purpose (google for 'dow optim'). As glycerine has taken over from PG as the advised diluent for medical inhalers, evidence that it may be associated with lipoid pneumonia would have significant implications for medical use.

This issue is one reason why it might be a good idea if glycerine-based e-liquid used by those with lung disease caused by smoking contained a small percentage of PG for its bactericidal and virucidal properties (apart from the issue of whether ecig use is advisable or not). Anyone with severe smoking-related lung disease such as late-stage COPD or emphysema must inform their consultant of their ecig use, in order that their health can be continuously monitored, since inhalation of anything at all with these diseases is contra-indicated. If pneumonia develops in someone at high risk of pneumonia due to chronic lung disease, most reasonable people would say that the last thing blame can be attached to is the ecig.

The MHRA was mentioned, but it is worth pointing out that they have no supervisory role with consumer products; they have as much right to regulate coffee and its dosages as e-cigarettes.

Dr McRobbie mentioned that he did not know if ecigs are regulated anywhere. Like virtually all medics he is not aware that the UK is the only country in the world where e-cigarettes are effectively regulated. The Department of Business have a regulatory programme in operation, as is appropriate for all consumer products, though they pay special attention to ecigs currently due to the interest.

The US situation was mentioned but the information seems outdated: ecigs have already been classified as a consumer tobacco product and will be regulated by the FDA as such. The AAPHP letter quoted was probably an old one since ecigs were classified as a tobacco product by 2011.
 
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Vocalek

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Dr. McRobbie does not seem to have bought in on the idea of tobacco harm reduction yet. I had the opportunity to review an article he wrote on withdrawal and implications for treatment. Despite describing the wide variations in duration and severity of withdrawal symptoms, he recommended using a "uniform approach to the treatment of tobacco withdrawal."

I commented that given length of suffering that can go on (presumably permanently for those with endogenous depression, ADHD, and other underlying conditions that nicotine helps to keep under control), it would seem to make more sense to individualize treatment to suit the needs of the patient.

The only treatments he went on to discuss were the usual suspects. And of course, the usual suspects (NRT, bupropion (Zyban/Wellbutrin), nortriptyline (Pamelor/Aventyl), and varenicline (Chantix/Champix) are not enough for those who cannot function when they become abstinent from nicotine.
 

Fiamma

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The only treatments he went on to discuss were the usual suspects. And of course, the usual suspects (NRT, bupropion (Zyban/Wellbutrin), nortriptyline (Pamelor/Aventyl), and varenicline (Chantix/Champix) are not enough for those who cannot function when they become abstinent from nicotine.

I'm ADHD and 72. I do not do well without some nicotine daily. I moved down to 4mg in my mix and it does well most days, if I come up on a bad day I have some 9mg for it. I tend to vape a lot at 4mg but that may be the flavors I'm after not so much the nic, or the hand to mouth and inhaling thing.

My feeling about nicotine, after reading up on some of the new research being done, is that it's fine to have and very beneficial for many, myself included.

No plans to ever go off nic.
 

rolygate

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There is a long road to travel before the medical community in general will admit that (a) nicotine is a normal part of the diet and everyone tests positive for it, (b) that some need more than others, and (c) that nicotine in reasonable amounts is not harmful. In fact we may never get there, due to its connection with smoking.

The first step would be to admit that harm reduction saves a vast amount more lives than a quit or die approach. This is intrinsically difficult for medics because in effect it is saying their therapies don't work and in some circumstances kill, and are out-performed by consumer products.

Perhaps when some ecigs become licensed therapies then movement in the right direction may be possible. If one licensed therapy is provably five times better than others, and has little or no health implications or side effects, then eventually it will be used more than others. At that point ecigs will be seen as a legitimate alternative. I don't think they will prove particularly good for cessation because the recipients will probably want to continue using them, but that's another story.

In any case there is no need for cessation if a therapy has side effects or health implications equivalent to zero for all practical purposes, and improves the subject's life. Another name for that is coffee.
 
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