TC can be OK on other chips, but generally run a bit "rough" in comparison. Hard to describe, but on the DNA board, you get tight regulation of the current to maintain the selected temperature/resistance (after all that's what the board is measuring and regulating of of). Some don't have preheat, which I find useful for larger mass coils. It's just a very smooth, very predicable vape, and no matter how long you hold the fire button, it won't get too hot the farther into the draw you get.
Other chips I've used include an Atheon in a CF4 18650 (OK TC, not terrific), Wismec boards in an RX200S and Presa (not bad, but I'd never trust the build quality for long term use) and a Smok board in an Alien. That one is kinda weird. I've been using it in TC with a SS notch coil and to me, the performance has been pretty good. Not a DNA but perfectly serviceable. HOWEVER, if you go to the Alien thread, you'll see some folks have serious issues with getting TC to work, so I won't vouch for it as my experience might just be the odd random board that was made that actually works.
The next big differentiating factor between DNA/non DNA is support. We all know lots of manufacturers that don't give the best support/warranty service. Evolv is very good about supporting their boards regardless of the builder, and I believe it's a one year warranty, but you can get your mod fixed if it craps out. Yihi also offers a 3 month warranty on the mod, but only if you bought it at the manufacturer's retail price and not if you get it on sale (that's what I've read, can't swear to that), which seems kinda crappy to me.