Don't let anyone tell you that nicotine is a poison...

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Uncle Willie

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I'll check Jessica Lange and raise you Helen Mirren .. who is, in fact, 68 ..

helen_mirren.jpg
 

Robino1

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Ah, topic anyone?

These ladies are beautiful but they also have stylists, dressers and yeah even fake hair pieces that get clipped in for those red carpet walks. And they are very photogenic.

Now, if you can find pictures of them without all that (besides the one that showed that lady in the bikini. I wanna look like that when I'm her age!) and still think they are hot...... Kudos.
 

hazarada

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But that's the other point of this thread, the nicotine toxicity data for people that everyone has gone by until now was not based on good science. wiki is an easy reference for the reported oral LD50's, and it's even been updated...the concentrations for skin may be different due to the slower absorption rates
LD50 means lethal dose for 50% of the sample base. Obviosuly they didn't test this on actual humans but extrapolated the data from animal testing while minding real life examples. Even if there are some people that are extremely resistant to nicotine, there are many more examples of people who are not. Scientific results are called to question every day yet drawing conclusions from questions themselves is just bad journalism.
and deleting the word poison might not be a bad idea- it's not informative. There are better descriptives that carry more information.
Its informative enough for people to use caution and possibly educate themselves on the subject matter, everybody is aware that they are slowly poisoning themselves one way or another and most do it in moderation but its a whole other thing to create the delusion that its harmless all together... I wouldn't give an e-cig to a child or indeed anyone who isn't a smoker already, would you?
 
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Robino1

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I really wouldn't say we are slowly poisoning ourselves. Nic leaves the system in a very short time period. We vape to keep the nic levels at a reasonable place so that we don't deal with the withdrawal.

If one gets nic sick it only takes a short while to get over it. Slowly poisoning hints at nic never leaving and building up over time. That is untrue.
 

hazarada

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Slowly poisoning hints at nic never leaving and building up over time. That is untrue.
That is true, bad wording on my part. What i ment was slowly damaging in general. And yes i do believe that nic by itself is still slightly damaging to the human body, even though much less dirty than analogues it still increases oxidative stress on the cells and stiffens arteries.
 
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Robino1

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That is true, bad wording on my part. What i ment was slowly damaging in general. And yes i do believe that nic by itself is still slightly damaging to the human body, even though much less dirty than analogues it still increases oxidative stress on the cells and stiffens arteries.

I'm not knowledgable on oxidative stress nor stiffening arteries so will leave those to others. However, I will say that most early studies done, equated nicotine and smoking as the same thing. They did not differentiate the two and lumped them into one item. Either smoking or nicotine.
 

DC2

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The OP is actively fighting the sensationalism of using the term "poison" to criticize e cigarettes.
This.

However I may have forgotten I was in a crowd of people who frequently handle 100mg strength nicotine.
So yes folks, wear your gloves, and keep it away from children.

I didn't think it was necessary to spell that out, but you never know which newbies are watching I guess.

If I had it to do over again I might have chosen a different title.
But I wouldn't change the content of the first post.
 

pcrdude

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Did anyone post a link to the most recent information about the toxicity of nicotine? I remember reading that the current LD50 estimate was based on some pretty questionable data, and poor science.

If you care to know, here is the editorial from the Archives of Toxicology:

How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century - Springer

Here are some of the findings:

The "old" lethal dose was reported to be 60 mg which is about 0.8 mg/kg, but was just a guess.

The author now estimates (based on real data), that the lethal dose is closer to 500-1000 mg which corresponds to an LD50 of 6.5–13 mg/kg.

I just thought y'all might like to know.

:D
 

JMarca

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I don't know if I would agree that is fact.
I think you would puke it up.

I know when I swallowed some chewing tobacco I puked.
I puked a lot.

But it's really hard to say, isn't it?
I mean, we haven't had any chance to find out.

And maybe that is the point I'm trying to make here.
:)

Pure liquid Nicotine would kill you if you drank it as you would a soft drink, honestly just inhaling the substance could make you pass out.
 

pcrdude

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Pure liquid Nicotine would kill you if you drank it as you would a soft drink, honestly just inhaling the substance could make you pass out.

I can't be certain, but I think nicotine would induce enough vomiting to get the absorbed dose low enough to be non-lethal.

I'm NOT willing to do the experiment.

;)
 

pcrdude

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I don't know anyone who handles 100% pure nicotine. For the DIYers, don't they start with 100 mg/ml and dilute from there?

A quick look at Wizard Labs shows that 100 mg/ml is the highest concentration they carry. Could that kill you if you drank it? I would guess that it would, but I don't know if the upchucking it would induce would be faster than absorbing a lethal dose.

BTW, I don't DIY, so the highest concentration I have around is 18 mg/ml. I don't drink it, and I wash my hands after I handle it to refill my toppers.
 

JMarca

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100mg/ml Nicotine CAN kill you, you don't even need to drink it. I do handle 100mg though, only because it's cheaper to get in bulk than something that has to be cut down. Simply inhaling it can leave devastating trauma to the lungs. I DIY, I recommend everyone start around 24mg or 36mg but even that can have some pretty bad results if ingested.
 

JMarca

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The post you quoted wasn't about pure liquid nicotine.

I understand but drinking any Nicotine is bad for you and you should be careful posting stuff like that plenty of people on this earth might get the urge to try to drink the stuff. Ingesting the stuff is bad for you, period.

Are you saying that simply inhaling the fumes from 100mg/ml strength liquid can do damage to your lungs?
I sure haven't ever heard that before.

Is this a well-known fact that every DIYer is aware of?


Are you serious? Have you ever had a bottle of 100mg in front of you and taken an inhale? The stuff makes you dizzy and light headed almost immediately.
 
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