Generally speaking, needs and wants don't change beyond a certain point .. food, shelter, relationships, etc .. our ability to simply live the life we want to live, now that can and does change ..
Our drive and ability are what keeps some of us going ..
'Making the best of the time we have left .. ??' That's a defeatist attitude .. in my World, it's 'Maximizing the time I have left ..'
Throwing the towel in and accepting what direction you think life is taking you is just not my way .. never has been .. I'll fight it till they peel me off the floor ..