Welcome to ECF and the wonderful world of vaping.
Simple Set Up is are 2 CTwists, a charter, and an EVOD or Pro Tank. Start with 24mg e-liq, something that sounds good to you. Don't try to mimic what you have been smoking, go outside the norm, if vanilla sounds good, get vanilla, if watermelon sounds good, get watermelon. I like the CTwists because they give you the ability to change the voltage to dialin the flavor. (start low, work up until you find what you like). I like the EVOD and ProTanks because they are bottom coils. Gravity does the job. Turn the tank upside down, fill it. Put the base on, then wait a few minutes for the wick to saturate, then GO. If it starts running out, turn the tank upside down, fill it and go! (on refills, you don't need to wait for the wick, it's already ready). Very simple to use. And they coils are replaceable fairly cheaply. If you're a tinkerer, they are also rebuildable.
Why to Ctwists? You will want one charging while you're using the other

(and you will learn that backup to your backups is a mantra here ) With regular cigs, if you run out, you run to the store. With E-cigs, if you run out, you might have to wait on the post.
Good Luck! And if you have questions, ask, plenty here willing to help!