nicotene delivery method and effects

[sincerelysasquatch]

So, I was trying to read up to see how more direct nicotene absorption varies from smoking in terms of hematologic effects, I have a blood clotting disorder called Factor V leiden and am especially supposed to stay away from nicotene due to increase in blood clotting risk.
The hemodynamic and hematologic effects of cigarette smoking versus a nicotine patch. - ResearchGate
I did find this, it's a study of hematologic effects of smoking vs. the patch. They actually found that the patch does not alter the blood nearly as much as smoking does. I did gather that much even though I don't know what all the terminology means. Now to google to see if any of this applies to me... and hope ecigarettes affect blood more like the patch (I assume they would).

 

[sincerelysasquatch]

Yep, increased fibrinogen from smoking is what increases clot risk, and purer nicotene from the patch doesn't increase it. Feeling better about nicotene than I was.

 

[bruiser]

Here's a new study on nicotine absorption.

Nicotine absorption from electronic cigarette use: comparison between first and new generation devices

 

[sincerelysasquatch]

Huh. I wondered how much nicotene came out in the vapor, since secondhand vapor on 18mg usually contains 1/10 the nicotene as secondhand smoke.

 

[roadkill46]

i'm on coumadin for live due to DVT's, not due to leiden factors, docs just say i have thick blood and i have an IT job so i'm in a chair a lot. ok i'll make a long story short, VA blood work came back 4 months ago showing a triglyceride level of 756!!!!!! supposed to be less than 120!!! well immediately they wanted to put me on tri-chlor anti triglyceride med. told them no, that i would do it by diet.

so i quit drinking totally, went back to vaping which i had not done since 2005 when this forum only had 1000 members and i had a 510! so i got an MVP2, some 24mg juice from the B&M shop we have here and then got on the Mayo Clinic and the Cleveland Clinic pages and found a triglyceride lowering diet.

seems that every tri has to have a fat cell to bind to, but every fat cell does not have to have a tri in it. turns out that black eyed peas have a protein in them that binds to the fat cell with the tri in it and it is eliminated in the normal way. also had to eat a lot of greens which threw my INR down way low (bad=thick) spose to be between 2-3.

well i went back to VA after 30 days, retook blood and that afternoon my doc called me and said it was impossible but my tri level was 112!!! Happy, happy, happy! So i proved them wrong but it really jacked up my INR.

took 2 months of every 2 week clinic visit for fingerstick (thankfully i work in the hospital) and it went up and down and finally leveled to 2.7 this month so only have to go back monthly. told the techs that do the INR's that i had quit smoking and they stated that would affect my INR also, actually making it thicker. well surprising was that my INR went up and was too thin, machine would not read it and had to go up to the lab for a draw.
they and my civilian PCP figure that the non smoking, non drinking happens to make my blood thinner even though i vape 24mg nic.

anyhoo, feel great now, gonna take me off some meds, can breathe, smell, taste, etc and never plan to go back to cigs again. bottom line, all of our bodies are different and react differently to things ie benadryl makes me hyper but puts my wife and grandkids out like a light!