Nicotine Vaccine Would You Get The Shot ( if Proven Safe) to Stop Vaping?

[ropetrick]

I would. Why be addicted if I don't have to be? I might continue vaping at 0 nic for a while, but I doubt that would last long.

I'm a little suspicious of the reports of heightened mental clarify from nicotine. It's certainly true for me, but only because I'm an addict and I get muddle-headed without a fix. Of course, any stimulant will help in this regard, but I have no intention of discontinuing my caffeine addiction, so I'll just stick with that for mental clarity. ;-)

 

[CES]

Absolutely not. When i first heard about it I looked up a couple of the original papers. First, I couldn't find anything that showed the specificity of the antobodies- that is I couldn't find anything published that shows the vaccine binds ONLY to nicotine and not to other things too. Second, one paper (study in rats) reported that the nicotine that is bound by the antibody and prevented from binding to the nicotinic receptors, is then sequestered in the fatty tissue of the body (i can find the paper again if anyone's interested). Third, i can't imagine anything more horrible than craving nicotine, and using more and more of it but not getting relief.


BTW, Dr. Cricken might check out this funding opportunity: Medication Initiative for tobacco Dependence (MITD): A New Product Development Partnership
(PDP)(UH2/UH3) http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-11-015.htmlthe original deadline has passed, but sometime deadlines are changed.

 

[cliff5550]

Voted "yes". If it was proven safe I'd take it right now!
I smoked for 45 years and I've vaped for 2 years. Nicotine be gone!

 

[Papa Lazarou]

I'd be very worried about potential long term side effects. The body has nicotine receptors for a reason (like cannabinoid and opioid receptors) and I can't help but feel that anything that alters your brain chemistry permanently by effectively disabling this mechanism is going to have some serious unintended consequences. Things like chantix and rimonabant with their history of causing serious side effects, illustrate what can happen when you block receptors. If this "vaccination" does the same thing but permanently then I find it very scary really.

So it's a "no way" from me. Even if the FDA tells everyone its safe..

 

[DragonflyVaper]

Bump.... Please take a second to respond, it may help to get an in-depth study on vaping.

 

[Grammie]

I would not! Consider the FDA's track record with prescriptions that have fatal side effects and are still on the market, while they are trying to ban a viable reduced harm product. No way, I do not trust them (meaning FDA).

 

[John Phoenix]

I have to ask...

How would a Nicotine vaccine even work?

Flu and other vaccines for Diseases work because they give you a small amount of the disease and thus let your body build up the proper immunity to them. This way, If you do get the disease, you body can fight it off and it will not kill you.

So.. How would a nicotine vaccine work? Choosing to ingest nicotine is Not a disease. The effect nicotine has on our central nervous system is not a disease. We choose to put small amounts of nicotine into our bodies all the time with no ill effects. If our bodies were going to build up an immunity to nicotine, it would have done so long ago.

What they are describing is Not a vaccine. They are describing a inhibitor of some sort that will block the effects of nicotine I assume. If they push this "vaccine" must they then label nicotine use a disease?

This seems like a ploy to manipulate the masses and force control out of the peoples hands - (your Freedom of choice) into the hands of a few. I say it stinks and no one should be for this.

 

[Stevew443]

There are many drugs on the market which have been "proven safe" and they have horrible side effects. One that comes to mind are the statin based meds for cholesterol. I have 2 personal friends who have had terrible and irreversable side effects from statins. I know that my chosen delivery system for nicotine is safe and it works for me. No way am I going to let Big Pharma into my blood stream if I can help it.

 

[Zal42]

I have to ask...

How would a Nicotine vaccine even work?

As I understand the article, calling it a vaccine is a little bit misleading. I think that what it does is to combine with nicotine in such a way as to make the molecules something the human immune system can attack. The body then treats them like any other biological invader. It is not a traditional vaccine, where you are intentionally exposed to a pathogen in a weakened form. You are already being exposed to the nicotine, this just makes it visible.

So, strictly speaking, it's not a vaccine. It does have similar effects to a vaccine, except that the effects are not long-lasting or permanent as with vaccines. I can see why they (the press) use that terminology, though. What other single word comes closer to explaining it?

 

[aziffel]

No,love the nic.,really enjoy the hobby of vaping,Yes the gadgets & stuff is a hobby
Like smoking,only tastes better

 

[pigelty]

Why would I want to get a NixVax? It's not a virus, it's a drug.

 

[CES]

I have to ask...

How would a Nicotine vaccine even work?

Flu and other vaccines for Diseases work because they give you a small amount of the disease and thus let your body build up the proper immunity to them. This way, If you do get the disease, you body can fight it off and it will not kill you.

So.. How would a nicotine vaccine work? Choosing to ingest nicotine is Not a disease. The effect nicotine has on our central nervous system is not a disease. We choose to put small amounts of nicotine into our bodies all the time with no ill effects. If our bodies were going to build up an immunity to nicotine, it would have done so long ago.

What they are describing is Not a vaccine. They are describing a inhibitor of some sort that will block the effects of nicotine I assume. If they push this "vaccine" must they then label nicotine use a disease?

This seems like a ploy to manipulate the masses and force control out of the peoples hands - (your Freedom of choice) into the hands of a few. I say it stinks and no one should be for this.

nicotine isn't a disease but the vaccine uses the the same principle. It tricks the body into recognizing nicotine as invasive and causes the body to make antibodies against the nicotine molecules. the antibodies bind to the nicotine and prevent the nicotine from crossing the blood brain barrier, and the nicotine that is bound by the antibodies is "disposed of" the same way any antibody bound molecule or protein is . The more nicotine you take into your system the more antibodies your body produces.

It's not a blocker, because it binds the nicotine itself rather than blocking receptor activation.

 

[lithiumdaze]

nope......

 

[Sophey]

No way -- for all the reasons already covered in this thread!

 

[Loveridden]

I would for sure take a safe vaccine that helped me quit nicotine. I enjoy vaping and all, but come on. I was a slave to analogs, now I am a slave to vaping. Yes it is much healthier than analogs, but I am still hooked on something. I would definitely take the vaccine.

 

[Vocalek]

I would for sure take a safe vaccine that helped me quit nicotine. I enjoy vaping and all, but come on. I was a slave to analogs, now I am a slave to vaping. Yes it is much healthier than analogs, but I am still hooked on something. I would definitely take the vaccine.

Hold it. Before you go there, consider this. Does nicotine help you to concentrate and pay attention? Does nicotine help you cope when you feel blue or anxious? If the answer to any of these is yes, know that how the vaccine works is that it blocks receptors so that nicotine no longer provides these beneficial effects. It doesn't just take away cravings, it works by making sure that nicotine doesn't help you any more.

I would personally not go anywhere near that vaccine. If I was willing to go through the rest of my life feeling confused and forgetful, and contemplating suicide, I'd just go cold turkey.

 

[Loveridden]

Hold it. Before you go there, consider this. Does nicotine help you to concentrate and pay attention? Does nicotine help you cope when you feel blue or anxious? If the answer to any of these is yes, know that how the vaccine works is that it blocks receptors so that nicotine no longer provides these beneficial effects. It doesn't just take away cravings, it works by making sure that nicotine doesn't help you any more.

I would personally not go anywhere near that vaccine. If I was willing to go through the rest of my life feeling confused and forgetful, and contemplating suicide, I'd just go cold turkey.

I'm not sure that nicotine actually helps me with these things, just makes me think it does while I am on it. Because I have quit before and after a couple weeks felt like a normal person again. I know I can concentrate without it. As for the blues, I would have to find other ways to help with that, and have found other successful ways to help with that before. Cigs are not the only thing that can help someone that is low. Yes I have many times gone to one in my sadness. But there are better alternatives to depression if you are really willing to try them! I would still take this vaccine!

 

[tanert007]

no. I simply started vaping because I like to smoke! Im not avoiding cigarettes, I did not ever smoke cigarettes. I also think that I have a tolerance to a degree to nicotine addiction. I can vape heavy for months and go on ten day vacations and stuff with no withdrawal at all. Its really a person to person thing. Sure take it if you are addicted and want to quit all smoking but why? Do what you enjoy.

 

[JC Okie]

Absolutely NO WAY. Period.

 

[Papa Lazarou]

In any case, it would appear it doesn't work yet (news release from last month) - Nabi Biopharmaceuticals - News Release